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Review: Lisinopril and Amlodipine





Summary: drug interactions are reported among people who take Lisinopril and Amlodipine together.

This review analyzes the effectiveness and drug interactions between Lisinopril and Amlodipine. It is created by eHealthMe based on reports of 10,045 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Lisinopril and Amlodipine >>>

What are the drugs

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. (latest outcomes from Lisinopril 99,129 users)

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine 46,546 users)

On Nov, 25, 2014: 10,045 people who take Lisinopril, Amlodipine are studied

Lisinopril, Amlodipine outcomes

Drug combinations in study:
- Lisinopril (lisinopril)
- Amlodipine (amlodipine besylate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lisinopril is effective20.00%
(3 of 15 people)
31.71%
(13 of 41 people)
37.50%
(12 of 32 people)
28.26%
(13 of 46 people)
37.84%
(28 of 74 people)
46.75%
(36 of 77 people)
56.10%
(23 of 41 people)
0.00%
(0 of 2 people)
Amlodipine is effective21.74%
(5 of 23 people)
29.82%
(17 of 57 people)
41.03%
(16 of 39 people)
30.51%
(18 of 59 people)
38.96%
(30 of 77 people)
54.17%
(26 of 48 people)
59.26%
(16 of 27 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypertensionRespiratory FailureFatigueAnxietyDepressionDepressionRenal Failure AcutePain
HypotensionLiver Function Test AbnormalOedema PeripheralPainMyocardial InfarctionAnxietyWeight DecreasedNausea
DizzinessHypertensionBlood Pressure IncreasedDepressionConstipationHypertensionFatigueDyspnoea
HeadacheMyocardial InfarctionBlood Cholesterol IncreasedHeadacheHypertensionMyocardial InfarctionBack PainDizziness
Blood Pressure IncreasedPneumoniaVomitingDizzinessDiarrhoeaEmotional DistressAlopeciaAnxiety
Weight DecreasedDizzinessCoughCerebrovascular AccidentAnxietyRenal FailureNeck PainFatigue
Loss Of ConsciousnessOedema PeripheralDiarrhoeaRenal ImpairmentCerebrovascular AccidentArthralgiaDizzinessOedema Peripheral
Ingrowing NailNauseaDry SkinTubulointerstitial NephritisGastrointestinal HaemorrhageDizzinessBlood Cholesterol IncreasedAsthenia
DehydrationRenal Failure AcutePneumoniaHaemoglobin DecreasedDizzinessLethargyDehydrationChest Pain
Drug IneffectiveMalaiseAlopeciaMusculoskeletal StiffnessOedema PeripheralChest PainPlatelet Count DecreasedHypertension

Drug effectiveness by gender :

FemaleMale
Lisinopril is effective41.35%
(55 of 133 people)
37.44%
(73 of 195 people)
Amlodipine is effective41.30%
(57 of 138 people)
36.98%
(71 of 192 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
NauseaDyspnoea
HypertensionNausea
DizzinessDizziness
Oedema PeripheralAsthenia
FatigueCardiac Failure Congestive
AnxietyAnxiety
Chest PainHypotension
DyspnoeaFatigue
FallRenal Failure Acute

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lisinopril is effectiven/an/a100.00%
(1 of 1 people)
50.00%
(3 of 6 people)
28.00%
(7 of 25 people)
11.11%
(7 of 63 people)
27.78%
(40 of 144 people)
26.22%
(70 of 267 people)
Amlodipine is effectiven/an/a100.00%
(1 of 1 people)
57.14%
(4 of 7 people)
33.33%
(9 of 27 people)
11.11%
(7 of 63 people)
27.40%
(40 of 146 people)
24.54%
(67 of 273 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Drug EruptionDiarrhoeaShockNephrogenic Systemic FibrosisHypertensionChest PainNauseaNausea
ErythemaIrritabilityHypertensionSkin HypertrophyAnxietyPainPainPain
MyopathyNauseaCompleted SuicideSkin IndurationDiabetes MellitusAnxietyDyspnoeaDyspnoea
PruritusHyperaesthesiaHypotensionArthralgiaVomitingDyspnoeaDizzinessFatigue
Renal Failure AcuteFeeling ColdCirculatory CollapseJoint Range Of Motion DecreasedRenal Failure AcuteNauseaHypertensionDizziness
Blood Creatinine IncreasedFatigueImpaired HealingSkin HyperpigmentationPainHypertensionOedema PeripheralAsthenia
Blood Creatine Phosphokinase IncreasedOedema MouthHistiocytosis HaematophagicPain In ExtremityHypoaesthesiaInjuryChest PainAnxiety
Ureteric CancerOedema PeripheralAcute Lung InjuryJoint ContractureType 2 Diabetes MellitusDiabetes MellitusAnxietyOedema Peripheral
DermatitisSwelling FaceCardiac ArrestAbasiaDizzinessMyocardial InfarctionMyocardial InfarctionCardiac Failure Congestive
Neuroleptic Malignant SyndromeTongue GeographicCardiotoxicityTendon DisorderHeadacheType 2 Diabetes MellitusFatigueFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lisinopril and Amlodipine?

You are not alone! Join a related mobile support group:
- support group for people who take Lisinopril and Amlodipine
- support group for people who take Amlodipine
- support group for people who take Lisinopril

Can you answer these questions (Ask a question):

  • I am on 2 x daily rifampin and 4 x daily cephalixin 500mg and and awake exhausted after 8-9 hours sleep and the fatigue is unbelievable all day every day, is this "normal" or should i investigate ore (1 answer)
    Had total knee replacement 11/12, bad from the start, knee swollen/hot/painful/unstable for most of 2 years before a mechanically successful Revision that found a loose patella and both ends of the prostheses loose. In spite of 10-12 aspirations and almost as many samples sent to labs for testing the result was always "no growth after a week". Following the revision, 10 days after, surgeons office called and says yes you have a staph E infection. Immediate therapy with 6 weeks of 3 X day IV PLUS 2 x per day oral Rifampin.
    IV over but now on the 2 X day Rifampin PLUS 4 X day 500mg cephalexin and the fatigue is unbelievable. Wake up exhausted after 8 hours sleep, daily hour plus mid afternoon naps.
  • Can the drug cellcept be used to treat pityriasis rosea
    Been diagnosed as Pityriasis Rosea. Dark patchy circles all over upper body and back. Condition has worsen, lasting over 5 months with outbreaks now on face and on scalp in hair. Some are painful raw blistery. Spreading on buttocks and a few on legs. Have tried several medications. Some have helped but none have cured. It is showing no signs of letting up. Dr has now prescribed Cellcept. Is this a safe drug for treatment for Pityriasis Rosea?
  • Plendil and pad interaction with arteries
    I'm currently taking 10 MG of Plendil with 20MG of Lisinopril. I've developed PAD a couple of years ago. I used to take 40MG of Lisinopril but since retiring my blood pressure had calmed down. My doctor reduced my Lisinopril to 20MG and kept the Plendil at 10MG. I was wondering is I should go back to the 40MG Lisinopril and discontinue the Plendil. I'm confused about the effects that Plendil has on my arteries. Does Plendil dialate the arteries ? If so, then wouldn't it be better that I stop the Plendil to reduce the pain of my PAD ?
  • Can unexplained hypertension be cause by a partial thyroidectomy?
    Doc is trying to figure out why the BP suddenly spiked. I started an exercise regimen after a stress test. I had to be on Metoprolol just to pass the test. Results were no heart-related issues. Lost 6lbs. since starting exercise and don't know if this is Thyroidal or not. No discussion with the doc yet of whether this is related to the thyroidectomy of the past.
  • I have had two surgerys to remove cancer in my bladder and am on warfarin for my afib. my bladder cannot seem to heal. i have blood in my urine and intermitent burning at the end of my penis. will the (2 answers)
    I have had two surgeries in the last 14 months to remove cancer from my bladder. Diagnosed with afib 16 months ago. Bladder is not healing due to the blood thinners, but I must keep my INR above 2.0. Every time I take the warfarin, I have more blood in my urine.

More questions for: Amlodipine, Lisinopril

You may be interested at these reviews (Write a review):

  • Bloody semen after taking amlodipine besylate
    Was started on Amlodipine Besylate 11-13-14. Now -not quite three weeks later- I have bloody semen (Hematospermia)ranging from light pink to dark red. It was fine, and normal before. I feel it is the medication causing this.
  • Experience with morphine and xanax
    I take MS contin for back pain, and xanax for anxiety. I was in the heart unit, and they decided to give me my morphine through the central line because I was having a lot of pain. The nurse pushed it in really slow, and afterword they asked me if I wanted my xanax, and I took it as well. 1 mg. I don't know how much morphine they gave me, but i began to hallucinate. I thought was dying..I remember trying to talk but the words wouldn't come out. I thought the nurse was asking me if I believed in Christ, and I said yes I love the Lord. At some point I was sure I had died, but I was calm and peaceful..there were several nurses in the room and I thought omg.. they've been keeping the secret of what happens when you die. I told them I was leaving because I wanted to go out in the hall, I was sure my deceased mother was out there looking for me, so I tried to remove my IV to get out of bed. They stopped me and I remember the nurse saying no its not your time. And I woke up the next morning.
  • Lipitor weight loss/ lisinipril ed issue (1 response)
    40 mg Lipitor for two months caused 8 pounds weight loss,thoughts of losing my mind ,racing heart rate,mental confusion,emergency visits twice,never in my life have gone to hospital by ambulance..5'11 178 BM 17 ,faithful gym rat ,all test ruled out physical issues,informed doctor, he didn't feel Lipitor was the cause,I stopped Lipitor 3 weeks later not losing weight ,bad dreams gone,feeling like myself again,hoping to regain the weight in time,Lisinpril 10 mg started two years ago ,has issues but did not connect until recently,3 months after taking started to have problems in the bedroom,only within the last 5 months did it occur to me was that was the cause of my sexual performance...had all test done testosterone ,blood work and all came back normal,stopped taking Lisinpril for 4 days a my manhood returned to normal!! Just spoke with doctor and says that shouldn't be????? Really ,he has since written me a new BP prescription,recent BP readings have been normal and will not take until BP rises....eating better ,with supplements ,,why Doctors don't believe the patient is incredulous ,thanks to sites like this people need to really question the health care their getting .....
  • Amlo dipine and terazosin
    I have taken combination since 04/13 I have experienced ED lower testosterone and elevated PSA. Prior to that I was taking terazosin and hydrochorizide without any side effects. I stop taking the amlodipine during a juice fast and my PSA levels decreased when I stopped fasting and returned to taking the amlodipine my PSA levels rose.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Amlodipine, Lisinopril

Comments from related studies:

  • From this study (1 day ago):

  • Hive like lesions all over body, very itchy.

    Reply

  • From this study (2 months ago):

  • combination of drugs does not seem to control blood pressure. BP varies during the day and changes markedly. High readings of 130/85 to lows of 80/70 over a brief (1 to 2 hour) time span. When BP gets low patient suffers from dizziness, nausea, feeling cold, and general weakness. Normal BP runs 100/80 to 110/85. Can combination of drugs be causing this effect?

    Reply

  • From this study (3 months ago):

  • Depression under control

    Reply

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Complete drug side effects:

On eHealthMe, Lisinopril (lisinopril) is often used to treat high blood pressure. Amlodipine (amlodipine besylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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