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Related topic: Doxazosin Mesylate, Lisinopril

Review: Lisinopril and Doxazosin Mesylate

This review analyzes the effectiveness and drug interactions between Lisinopril and Doxazosin Mesylate. It is created by eHealthMe based on 1,834 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 6, 2014: 1,834 people who reported to have interactions when taking Lisinopril, Doxazosin Mesylate are studied

Trend of Lisinopril, Doxazosin Mesylate's drug interactions, side effects and effectiveness reports (4475780)

Drug combinations in study:
- Lisinopril (lisinopril)
- Doxazosin Mesylate (doxazosin mesylate)

eHealthMe real world results:

Most common interactions experienced by people in the use of Lisinopril, Doxazosin Mesylate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)457
Hypotension (abnormally low blood pressure)344
Drug Ineffective328
Nausea (feeling of having an urge to vomit)284
Drug Interaction272
Cardiac Failure Congestive240

Most common interactions experienced by people in long term use of Lisinopril, Doxazosin Mesylate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Tubulointerstitial Nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)45
Glomerular Filtration Rate Abnormal26
Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)8
Erectile Dysfunction6
Loss Of Consciousness4
Angioedema (rapid swelling of the dermis)4
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)4
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)3

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Doxazosin Mesylate0.00%27.27%18.18%36.36%18.18%

Top conditions involved for these people * :

  1. Hypertension
  2. Type 2 diabetes mellitus
  3. Diabetes mellitus
  4. Atrial fibrillation
  5. Blood cholesterol increased

Top co-used drugs for these people * :

  1. Cardura
  2. Aspirin
  3. Zestril
  4. Atenolol
  5. Furosemide

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Lisinopril (lisinopril) is often used to treat high blood pressure. Doxazosin Mesylate (doxazosin mesylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • My 73 year old father in law takes all of these medications and he is not doing well. He has severe dementia that has come on in the last 6-8weeks. Each week he seems to be doing worse. He had gallbladder surgery September 1st, and has lost 65 pounds. At first, I thought he just wasn't feeling well due to the gallbladder surgery. On his birthday, 10-28 I realized something was very wrong. We have been going to doctors since and haven't gotten any real answers. I am concerned that he takes so many blood pressure medicines. What is clonidine used for? He takes .2 mg three times a day. He barely speaks is very weak, and has to be fed. We had an MRI and brain scan done. The neurologist we saw thinks it's frontal lobe dementia or that he may have fell and hit his head, he did not think it was a stroke. My question is if it's dementia wouldn't we have noticed over time. My father in law was sharp as a signs of memory loss at all. At first we thought he might have had a slight stroke but as time has gone on it seems to be something much worse. Any help. ideas, suggestions are appreciated. We are waiting to see another neurologist. Thank You!


    Margaret Boardman on Mar, 11, 2012:

    hi, i have recently gone thru problems w/ drug interactions. most pharmacists and doctors are unaware of MOST interactions that can cause severe probs. for instance, Tylenol can cause hypertension!! who would have thought?

    i grilled my brother, (PHD pharmacist)then took his info and went on line and was able to teach him a thing or two!!

    my b/p has been controlled on 2 meds for quite sometime, but high doses. atenelol at high doses can cause HTN! as well as severe panic disorders! other drugs, and this is not all, can cause HTN, like ibuprofen (fluid retention) vicodin, lorazepam w/ prilosec, antidepressants Like wellbutrin, most of the things i was taking was keeping my b/p way up!! what i did was go on line and read as many articles as i could by Googleing the med name along w/ a symptom, like, omeprezole and hypertension, or lorazepepam with another med, etc, i kept this up until i got enough info to put it all together and came up w/ my own resolution, then discussed it w/ my brother and doc. i am now on fewer meds and lower doses and am much better!!

    NEVER quit a med cold turkey! discuss weaning of all non essentials, one at a time. good luck. ALL meds are essentially poison and should be last resort. most mds and many pharmacists don't know much about multiple meds taken together. research and educate them. be proactive in your own health. it saved my life. RN, retired


    Karen on Jul, 2, 2012:

    my mom has had the same - was as bright as a button and then suddenly confused and this has got worse - gp is crap - what has happened with your father - im worried that i am losing my mom - yesterday she slept all day had problems eating and drinking as she couldnt hold the cup and kept falling asleep
    would love to know what has happened with your dad


    Cathy on Oct, 30, 2012:

    I am just on my journey learning about these medications. My mother (85) is on many of these, and since she started Dilitiazem, is when many of her problems began. Then more meds to treat the side effects. From what I have found out is Dilitiazem was never intended for long term use, and will cause white matter in the brain, which is essentially dimentia. Which they have diagnosed her with. I believe this medication has created this problem. Dilitiazem also causes rash, dizziness and swelling which she also has, again with additional meds to treat these side effects. And yes, working with a doctor to reduce these medications.


    Lucy on Nov, 13, 2012:

    My husband as well as a friends husband had been taking propecia/finastride for prostate. My husband has suffered severe memory loss in short time, the other man is not even and disabled from medication, he can't even remember where his lives, this drug has some good for prostate, but is my opinion is more harmful, and should be pulled from shelf, I hope you find the answer, let me know. Lucy


    yumishi on Nov, 20, 2012:

    Hi ,
    About your 73 year old father in law, Statines can cause dementia like symptoms(side effect) and severe muscle damage it also can cuase kidney and liver faillure !!! So first quit this poison and recommend also to quit all medication for a while(only maybe the one or two he really needs) ...people need cholesterol but nowadays they are overmedicating everyone and people get medication for all negative side affects caused by the medication .Best thing is start from scratch ...see if there is any improvement and then look if and what he really needs . For now it is very likely medicines are doing more wrong then good everything on the internet you can about statines (just type statines dangerous !!) and all the other pills your dad is getting .....think your father in law is victim of overmedication and especially from statines ...people over 50 donĀ“t need statines they are doing more wrong then good !!! (almost lost my husband by the poisoning effect of statines !!


    frank on Jan, 30, 2013:

    I was on Allopurinol 300 for about 5 years. My doctor took me off about a year ago. I have just been told that I have bladder cancer. Seems more & more cases are coming up?


    annonymous on Feb, 20, 2013:

    Is the man drinking any water? If he's not hydrated, memory loss and Dementia symptoms could occur.


  • From this study (1 year ago):

  • dox taken at night on continuious vivid dream of galloping on horseback all night long
    lis taken in morning systems become eleveated
    frus when edema starts


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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Related studies

- Doxazosin Mesylate side effects
- Lisinopril side effects



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