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Review: taking Lortab and Adderall 20 together

Summary: drug interactions are reported among people who take Lortab and Adderall 20 together.

This review analyzes the effectiveness and drug interactions between Lortab and Adderall 20. It is created by eHealthMe based on reports of 793 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 3, 2015: 793 people who take Lortab, Adderall 20 are studied

Lortab, Adderall 20 outcomes

Drug combinations in study:
- Lortab (acetaminophen; hydrocodone bitartrate)
- Adderall 20 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lortab is effective42.42%
(14 of 33 people)
(18 of 39 people)
(12 of 27 people)
(10 of 26 people)
(23 of 47 people)
(18 of 25 people)
(4 of 10 people)
(0 of 2 people)
Adderall 20 is effective50.00%
(11 of 22 people)
(21 of 38 people)
(16 of 32 people)
(24 of 45 people)
(23 of 48 people)
(8 of 16 people)
(8 of 9 people)
(1 of 1 people)

Drug effectiveness by gender :

Lortab is effective47.97%
(71 of 148 people)
(28 of 61 people)
Adderall 20 is effective53.64%
(81 of 151 people)
(30 of 60 people)

Drug effectiveness by age :

Lortab is effective0.00%
(0 of 1 people)
(1 of 4 people)
(25 of 116 people)
(34 of 139 people)
(22 of 78 people)
(13 of 61 people)
(4 of 18 people)
Adderall 20 is effective0.00%
(0 of 1 people)
(4 of 6 people)
(35 of 141 people)
(33 of 141 people)
(21 of 79 people)
(15 of 62 people)
(4 of 15 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Deep Vein ThrombosisDizzinessPainAbdominal PainPainInsomniaNecrotizing FasciitisPain
PainHeadachePyelonephritisDizzinessCholecystitis ChronicPainCfsAnxiety
InjuryAnxietyVomitingPain In ExtremityCholelithiasisEmotional DistressTachycardiaHeadache
DepressionPainAbdominal PainNauseaInjuryNumbness And TinglingProteinuria PresentDepression
Suicide AttemptNauseaNauseaInsomniaInsomniaMuscle PainDiverticulitisChest Pain
Drug IneffectiveFatigueDiarrhoeaPyelonephritisAnxietyCholecystitis ChronicConfusionFatigue
Unresponsive To StimuliConstipationCholecystitis ChronicVomitingConstipationAnxietyEmotional DistressInsomnia
PruritusAnhedoniaNephrolithiasisRenal ColicGallbladder DisorderNauseaNauseaNausea
ArthralgiaHot FlashesRenal ColicDiverticulumNauseaGallbladder DisorderDizzinessPain In Extremity
Procedural ComplicationGeneral Physical Health DeteriorationMuscle SpasmsMuscle SpasmsDepressionDizzinessDry MouthFall

Most common drug interactions by gender * :

PainMultiple Drug Overdose
Chest PainRhabdomyolysis
Pain In ExtremityDrug Abuse

Most common drug interactions by age * :

n/an/aPainHeadacheDeep Vein ThrombosisInsomniaAnxietyCompleted Suicide
Cholecystitis ChronicDrug ToxicityHeadacheChest PainInsomniaPain In Extremity
VomitingAnxietyChest PainPyrexiaSomnolenceDepression
Emotional DistressNauseaPainCoughHeadacheBronchitis
Gallbladder InjuryDizzinessVomitingDyspnoea ExertionalDepressionHerpes Zoster
DiarrhoeaVomiting Of MedicationDyspnoeaCardiomegalyPainChronic Obstructive Pulmonary Disease
Abdominal PainDepressionPulmonary EmbolismPalpitationsMenopauseAsthenia
NauseaOverdoseArthralgiaDilatation VentricularChest PainPatella Fracture
Pain In ExtremityInjuryAstheniaTricuspid Valve IncompetenceOsteoarthritisBlood Alkaline Phosphatase Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lortab and Adderall 20?




You are not alone! Join a related support group:
- support group for people who take Adderall 20
- support group for people who take Lortab

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Lortab (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Adderall 20 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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