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Review: Lortab and Amoxicillin

Summary: drug interactions are reported among people who take Lortab and Amoxicillin together.

This review analyzes the effectiveness and drug interactions between Lortab and Amoxicillin. It is created by eHealthMe based on reports of 2,431 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Lortab and Amoxicillin >>>

What are the drugs

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Lortab 17,008 users)

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. (latest outcomes from Amoxicillin 24,153 users)

On Nov, 22, 2014: 2,431 people who take Lortab, Amoxicillin are studied

Lortab, Amoxicillin outcomes

Drug combinations in study:
- Lortab (acetaminophen; hydrocodone bitartrate)
- Amoxicillin (amoxicillin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lortab is effective42.42%
(14 of 33 people)
(1 of 2 people)
(2 of 2 people)
(1 of 2 people)
(2 of 2 people)
Amoxicillin is effective31.25%
(10 of 32 people)
(0 of 2 people)
(0 of 2 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainAnxietyPainCholelithiasisCholecystitis ChronicAnxietyCholelithiasisPain
Cholecystitis ChronicPainPain In ExtremityGallbladder DisorderInjuryCholecystitis ChronicBack PainAnxiety
AnxietyInjuryAbdominal PainCholecystitis ChronicDeep Vein ThrombosisDepressionPulmonary EmbolismInjury
Gallbladder DisorderDeep Vein ThrombosisVomitingHeart Rate IrregularCholelithiasisBiliary DyskinesiaVomitingBack Pain
CholelithiasisPulmonary EmbolismCholecystitis ChronicSyncopePainLoss Of ConsciousnessPainOsteonecrosis Of Jaw
Abdominal PainDepressionDiarrhoeaCerebrovascular AccidentPulmonary EmbolismPainChest PainArthralgia
NauseaConstipationMusculoskeletal PainCholecystitisEmotional DistressGeneral Physical Health DeteriorationNauseaAnaemia
InjuryScarNauseaRenal Failure ChronicPain In ExtremityAbdominal Pain UpperCholecystitisNausea
VomitingEmotional DistressIleusRenal ImpairmentGait DisturbanceFallGastric DisorderDepression
Emotional DistressAbdominal PainPleural EffusionLethargyNauseaGallbladder InjuryCholecystitis ChronicDyspnoea

Drug effectiveness by gender :

Lortab is effective50.00%
(11 of 22 people)
(9 of 19 people)
Amoxicillin is effective33.33%
(6 of 18 people)
(4 of 19 people)

Most common drug interactions by gender * :

Back PainFatigue
Osteonecrosis Of JawBack Pain
NauseaOsteonecrosis Of Jaw
DepressionOedema Peripheral

Drug effectiveness by age :

Lortab is effectiven/a0.00%
(0 of 1 people)
(1 of 3 people)
(10 of 23 people)
(1 of 8 people)
(5 of 7 people)
(2 of 6 people)
(1 of 4 people)
Amoxicillin is effectiven/a0.00%
(0 of 1 people)
(0 of 3 people)
(7 of 19 people)
(2 of 9 people)
(1 of 6 people)
(0 of 6 people)
(0 of 3 people)

Most common drug interactions by age * :

PancreatitisInflammatory Bowel DiseaseCholecystitis ChronicCholecystitis ChronicAnxietyPainPainPain
WheezingCrohn's DiseasePainPainPulmonary EmbolismAnxietyAnxietyAnxiety
Supraventricular ExtrasystolesStomatitisNauseaInjuryPainInjuryOsteonecrosis Of JawInjury
Pleural EffusionDehydrationAnxietyCholelithiasisNauseaBack PainInjuryAnaemia
Pulmonary CongestionHeart Disease CongenitalGallbladder DisorderPulmonary EmbolismCholecystitis ChronicNauseaBack PainArthralgia
FatigueDrug Exposure During PregnancyInjuryGallbladder DisorderDepressionChest PainAnaemiaOsteonecrosis Of Jaw
Nodal RhythmAbdominal Pain UpperDeep Vein ThrombosisCholelithiasisOsteonecrosis Of JawOsteoarthritisBack Pain
AcidosisVomitingAbdominal Pain UpperDyspnoeaDepressionHypoaesthesiaFall
BronchiolitisCholelithiasisAnxietyHeadacheArthralgiaBone DisorderFatigue
Dilatation VentricularAbdominal PainVomitingBack PainAnaemiaEmotional DistressBone Disorder

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lortab and Amoxicillin?

You are not alone! Join a related mobile support group:
- support group for people who take Lortab and Amoxicillin
- support group for people who take Amoxicillin
- support group for people who take Lortab

Can you answer these questions (Ask a question):

More questions for: Amoxicillin, Lortab

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    Just want to bleed out and not hurt anymore and be so scared to leave my house or sleep. I just want to sleep forever.

More reviews for: Amoxicillin, Lortab

Comments from related studies:

  • From this study (3 months ago):

  • Taking longer to empty bladder and doesn't seem to completely empty


  • From this study (10 months ago):

  • Post mouth surgery.


  • From this study (2 years ago):

  • On third day of taking both drugs, woke up with swollen, red puffy sunburn like experience on face, that is warm to the touch. It is not itchy.


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Complete drug side effects:

On eHealthMe, Lortab (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Amoxicillin (amoxicillin) is often used to treat infection. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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