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Review: taking Lortab and Coreg together

Summary: drug interactions are reported among people who take Lortab and Coreg together.

This review analyzes the effectiveness and drug interactions between Lortab and Coreg. It is created by eHealthMe based on reports of 2,134 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from 17,012 Lortab users)

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. (latest outcomes from 23,794 Coreg users)

On Feb, 1, 2015: 2,134 people who take Lortab, Coreg are studied

Lortab, Coreg outcomes

Drug combinations in study:
- Lortab (acetaminophen; hydrocodone bitartrate)
- Coreg (carvedilol)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lortab is effective42.86%
(3 of 7 people)
(2 of 3 people)
(1 of 2 people)
(3 of 7 people)
(3 of 14 people)
(5 of 9 people)
(2 of 2 people)
(1 of 1 people)
Coreg is effective100.00%
(1 of 1 people)
(3 of 5 people)
(1 of 5 people)
(2 of 8 people)
(6 of 11 people)
(2 of 3 people)
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure AcuteAbdominal PainChest PainMyocardial InfarctionAnaemiaConfusionSwelling In The AbdomenPain
Confusional StateFaeces DiscolouredCoronary Artery DiseaseCoronary Artery DiseaseExhaustion, Fatigue, Lethargy, Tiredness, WearinessDry SkinFrequent Or Urgent UrinationCardiac Failure Congestive
Blood Pressure DecreasedCardiac Valve DiseaseAngina PectorisHyperlipidaemiaHypotensionDry MouthNausea And VomitingDyspnoea
Weight IncreasedBlood Bilirubin IncreasedSudden DeathIschaemic CardiomyopathyChest PainSwelling Of The Ankles - Feet - LegsSwelling Of The Ankles - Feet - LegsNausea
Drug IneffectiveJaundiceDiabetes MellitusHeart Rate IrregularDyspnoeaSwelling In The AbdomenDry MouthAnxiety
PainPulmonary CongestionMusculoskeletal DiscomfortChest PainAbdominal PainWeight GainWeight GainAsthenia
SomnolenceOcular IcterusRotator Cuff SyndromeAtrial FibrillationNight SweatsNight SweatsDry SkinAnaemia
DepressionOedemaRoad Traffic AccidentLung InjurySleepySperm Count DecreasedSleepyBack Pain
Faecal IncontinenceAnorexiaMyocardial InfarctionRenal ImpairmentDisease ProgressionOedema Peripheral
Mental Status ChangesWeight IncreasedFatigueRenal DisorderVomitingPneumonia

Drug effectiveness by gender :

Lortab is effective43.48%
(10 of 23 people)
(10 of 22 people)
Coreg is effective55.00%
(11 of 20 people)
(6 of 16 people)

Most common drug interactions by gender * :

Cardiac Failure CongestivePain
PainCardiac Failure Congestive
Oedema PeripheralAtrial Fibrillation
DiarrhoeaBack Pain

Drug effectiveness by age :

Lortab is effectiven/an/an/an/a0.00%
(0 of 9 people)
(4 of 8 people)
(5 of 17 people)
(11 of 32 people)
Coreg is effectiven/an/an/an/a12.50%
(1 of 8 people)
(2 of 7 people)
(5 of 15 people)
(9 of 24 people)

Most common drug interactions by age * :

Mental Status ChangesFatigueChest PainCardiac Failure CongestivePainNauseaPainCardiac Failure Congestive
Myocardial InfarctionDyspnoeaPallorBronchitisAnxietyPainAnxietyDyspnoea
Tricuspid Valve IncompetenceMultiple InjuriesNauseaInsomniaRash PruriticDiarrhoeaCardiac Failure CongestivePain
Ventricular FibrillationMental Status ChangesPathogen ResistanceHypertensionNauseaMyocardial InfarctionOedema PeripheralAsthenia
HypoglycaemiaHypoglycaemiaPolycythaemiaUrinary Tract InfectionOedema PeripheralVomitingAnaemiaFall
Sinus TachycardiaCroup InfectiousProductive CoughMulti-organ FailureVomitingAnxietyDyspnoeaNausea
Circulatory CollapseCardiomegalyMyalgiaInfluenza Like IllnessPain In ExtremityInjuryNauseaDizziness
Cardiac ArrestCardiomyopathyPlatelet Count DecreasedIntracardiac ThrombusChest PainCardiac Failure CongestiveAbdominal PainAtrial Fibrillation
FatigueCongestive CardiomyopathyMalnutritionOrthopnoeaHypertensionCoronary Artery DiseaseHypertensionPneumonia
Aortic Valve IncompetenceMyocardial InfarctionHypovolaemiaPresyncopeHypotensionPneumoniaDiarrhoeaBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lortab and Coreg?

You are not alone! Join a related mobile support group:
- support group for people who take Lortab and Coreg
- support group for people who take Coreg
- support group for people who take Lortab

Can you answer these questions (Ask a question):

More questions for: Coreg, Lortab

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More reviews for: Coreg, Lortab

Comments from related studies:

  • From this study (8 months ago):

  • symptoms came on suddenly after using Fentanyl patches, but did not change after stopping use of patch


  • From this study (9 months ago):

  • My levels of TSH have fluctuated from optimal .94 to 8.00 after thyroidectomy from Graves Disease in 2012. Have become disinterested in things I used to love to do and have a hard time staying awake at work in the afternoons. I have taken the synthroid religiously as I am supposed to. I also take an iron supplement, B-complex in hopes that it would help my energy level. I also take valium to sleep at night and narco for pain.


  • From this study (9 months ago):

  • All of the symptoms I listed started after I began taking Ambien. I quit taking it after about 2 months. The symptoms have not gone away after 60 days.


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Complete drug side effects:

On eHealthMe, Lortab (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Coreg (carvedilol) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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