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Review: taking Lyrica and Alpha - Lipoic Acid together

Summary: drug interactions are reported among people who take Lyrica and Alpha - Lipoic Acid together.

This review analyzes the effectiveness and drug interactions between Lyrica and Alpha - Lipoic Acid. It is created by eHealthMe based on reports of 39 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Lyrica and Alpha - Lipoic Acid >>>

What are the drugs

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,581 Lyrica users)

Alpha - lipoic acid has active ingredients of alpha - lipoic acid. It is often used in diabetes. (latest outcomes from 116 Alpha - lipoic acid users)

On Jan, 30, 2015: 39 people who take Lyrica, Alpha - Lipoic Acid are studied

Lyrica, Alpha - Lipoic Acid outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Alpha - Lipoic Acid (alpha - lipoic acid)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effectiven/a0.00%
(0 of 3 people)
n/an/an/a0.00%
(0 of 1 people)
n/an/a
Alpha - Lipoic Acid is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
n/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveThrombocytopenian/an/an/aPancytopenian/aBacteraemia
Foot PainStaphylococcal InfectionThrombocytopenia
Eyes - Sensitive To LightBacteraemiaDizziness
HeadacheAcute Lymphocytic Leukaemia RecurrentStaphylococcal Infection
Fatigue - ChronicFatigue - ChronicPain In Extremity
Pain In JawPain - MusclesNausea
Pain - MusclesPain In JawParaesthesia
Eyes - DryFoot PainBack Pain
DiarrheaHeadacheHeadache
Eye HaemorrhageFlatulence (flatus)Gait Disturbance

Drug effectiveness by gender :

FemaleMale
Lyrica is effective0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
Alpha - Lipoic Acid is effectiven/a0.00%
(0 of 1 people)

Most common drug interactions by gender * :

FemaleMale
ThrombocytopeniaDizziness
BacteraemiaStatus Epilepticus
Staphylococcal InfectionNeuralgia
Pain In ExtremityHypotension
FallGait Disturbance
HeadacheDysphagia
NauseaApathy
Back PainSomnolence
Drug IneffectiveMuscle Tightness
DizzinessAltered State Of Consciousness

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/an/an/an/a0.00%
(0 of 12 people)
0.00%
(0 of 1 people)
Alpha - Lipoic Acid is effectiven/an/an/an/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/an/aHyperglycaemiaPainBacteraemiaDizziness
ThirstGait DisturbanceThrombocytopeniaGait Disturbance
CyanosisFibromyalgiaStaphylococcal InfectionHypotension
MalaiseMalaiseHeadacheMuscle Tightness
Drug IneffectiveFatigueNauseaStatus Epilepticus
Systemic Lupus ErythematosusPain In ExtremityApathy
Cognitive DisorderDysgeusiaDrug Ineffective
Memory ImpairmentBack PainNeuralgia
DepressionAcute Lymphocytic Leukaemia RecurrentParaesthesia
FallHyperchlorhydriaSomnolence

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lyrica and Alpha - Lipoic Acid?

You are not alone! Join a related mobile support group:
- support group for people who take Lyrica and Alpha - Lipoic Acid
- support group for people who take Alpha - Lipoic Acid
- support group for people who take Lyrica

Recent conversations of related support groups:

  • Support group for people who take Lyrica
    I have gained about 35 pounds, and I have the cognitive effects listed in the prescribing information--problems with thinking and concentration." I've been off Lyrica once, and the side effects went away, but I couldn't get out of bed in the morning

Can you answer these questions (Ask a question):

  • Does lyrica cause neutropenia and if it does, how long does it take to subside after stopping the drug?
    The patient is a 28 year old female who has been involved in a horrific car accident back in February 7th 2014. She had bilateral femural fracture along with fractured right tibia and fibula in addition to right humerus. However, to make it short, after treatment, the outcome was not acceptable with various complications. The patient is scheduled for another surgery, however, her CBC shows neutropenia (3.4).
  • Can i take a steroid while taking xarelto (1 answer)
    I took prednisone for constant cough. had 3rd surgery on back one year ago. Had to patch spinal cord. Got blood clots. Had pulmonary embolism. Now have severe bronchitis. I know the prednisone will take care of cough, but what else?
  • How much do i decrease at a time, and how long should the decrease last. lyrica, and symbalta
    After the extreme weight gain. The dizziness. The exhaustion all the time. Nausea consistently before, during and after eating. Extreme lower back pain. Leg pain, cramping, and jerking. Now her oxygen levels are from 82-95 tops with the bi-pap. She finally wants to quit taking Lyrica, cymbalta, forteo, and all the prescription stomach meds she has to take because she's on them. I am figuring lowering 25 mgs at a time and staying there for 28 days with the Lyrica. She's been on Lyrica and cymbalta for 5-1/2 years. Any help would be greatly appreciated. I know with the severity of her problems she will not make it another three years. The confusion she's in approximately 70% of the time I'm going to lose her. She woke up and was totally confused while I was in the restroom for a couple minutes and I wound up rushing her to the hospital where she died in my arms before bringing her back three times because she took 17-15 mg oxycodone thinking they were her night pills. The reason I'm going into so much detail is to show the severity. Every doctor I've spoken with has said 25-50 mgs for two weeks is the norm. I told her doctor when he bumped her from 75 to 150 she wouldn't be able to take it. I am absolutely positive her body will go through major withdrawals and I can't have that happen. Thank you for taking the time to read everything I've written.
  • Any information on deaths from taking lyica and high doses of alprazolam (1 answer)
    My Mother was a healthy 89 yr old with no healt issues, she was put on anxiety medicine, which she took regularly. She was also taking Lyric and had just started her Macular degeneration shots. She was prone to bladder infections and we went to the dr. for that, labs showed high calcium, within one week I had to take her to the emergency room, within one day she was on oxygen, within three days she was in the ICU intubated and unresponsive. She remained in ICU for 4 days had renal failure and died two days later.
  • Is pregabalin aggravate the symptoms of bph?
    I am having BPH. for foot pain doctor prescribes Pregabalin. that night the symptoms of BPH worsens. Is it due to Pregabalin? pl.write.

More questions for: Alpha - Lipoic Acid, Lyrica

You may be interested at these reviews (Write a review):

  • Alpha lipoic acid facial swelling/ especially eyelids
    I took this three times (several months apart) - took one 600 capsule. The following morning I had a very swollen face, especially my eyelids and upper cheeks. I only took again because several doctors had assured me that the reaction was most likely food or other and not the Alpha Lipoid Acid. I'm 100% sure that that was what caused the reaction.
  • Blood sugar level while taking veltrex
    I been taking Veltrex for a viral infection in my eye for 3 days and today my blood sugar was 448.My normal blood sugar runs around 146.
  • Leg pain especially near knees after taking lyrica
    Had to stop taking Lyrica due to joint pain in both legs. Difficult to get up from sitting position to stand. Ache in knee's can't relax to sleep. Motrin and vicodin not helping with pain. Also have applied muscle cream not working for pain. Have been off the lyrica for 3 months with no let up in pain. Did not have this pain before taking lyrica.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.

More reviews for: Alpha - Lipoic Acid, Lyrica

Comments from related studies:

  • From this study (1 year ago):

  • Eye lids develop an itch, then become red. A few days later that crusts and flakes.

    Reply

  • From this study (3 years ago):

  • my stomach hurts and feel I must eat to stop the hungry feeling but eating does not help. Feelings of anger and hatred. Disturbing and very vivid dreams. High blood pressure. Holding my breath and not being able to breath normally. Anxiety. Burping.

    Reply

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Alpha - Lipoic Acid (alpha - lipoic acid) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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