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Review: Lyrica and Ibuprofen

This review analyzes the effectiveness and drug interactions between Lyrica and Ibuprofen. It is created by eHealthMe based on 2,122 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 1, 2014: 2,122 people who reported to have interactions when taking Lyrica, Ibuprofen are studied

Trend of Lyrica, Ibuprofen's drug interactions, side effects and effectiveness reports (4432133)

Drug combinations in study:
- Lyrica (pregabalin)
- Ibuprofen (ibuprofen)

eHealthMe real world results:

Most common interactions experienced by people in the use of Lyrica, Ibuprofen:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pain1,442
Anxiety1,253
Dyspnoea (difficult or laboured respiration)976
Fatigue (feeling of tiredness)723
Dizziness641
Nausea (feeling of having an urge to vomit)638
Back Pain604
Depression600
Hypoaesthesia (reduced sense of touch or sensation)596
Injury560

Most common interactions experienced by people in long term use of Lyrica, Ibuprofen:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pain74
Somnolence (a state of near-sleep, a strong desire for sleep)33
Vision Blurred28
Dizziness28
Drug Ineffective26
Visual Impairment24
Depression22
Insomnia (sleeplessness)22
Cholecystitis Chronic (long lasting infection of gallbladder)20
Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood)20

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Lyrica7.14%7.14%57.14%14.29%14.29%
Ibuprofen0.00%0.00%66.67%33.33%0.00%

Top conditions involved for these people * :

  1. Pain
  2. Fibromyalgia
  3. Neuralgia
  4. Hypertension
  5. Depression

Top co-used drugs for these people * :

  1. Motrin
  2. Aspirin
  3. Neurontin
  4. Ambien
  5. Zometa

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Ibuprofen, Lyrica

You can also:

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 months ago):

  • at first I lost hearing on my left ear for several weeks with pain, eventually hearing came back. Then it occurred on my right, eventually recovered hearing. But both ears had extreme pressure and now tubes were inserted. Left ear recovered from pressure but continue to have pain. Right ear sounds as if I have water inside and I hear myself as if I'm talking inside a closet or enclosed room, only in my right ear. But both ears hurt like if my ears are being pulled downward.

    Reply

  • From this study (1 year ago):

  • Doc has recommended small dose Lexapro for anxiety (I am 82 yrs old) and I am concerned that this will cause some constipation and/or fogginess that will make me unsteady on my feet

    Reply

  • From this study (1 year ago):

  • Covered in rash over half my body after starting Topiramate. Have also tested positive for Lupus.

    Reply

    Patient Dar on Feb, 18, 2013:

    Complete list of symptoms that docs really don't want to hear at one time. Been going on for over 15 years. Headaches, low BP with high spikes that make me fall down, heart racing, hot flashes not related to menopause, cysts on top of each kidney, low white count and platelet count often, sores on head in nose and on face, so tired don't feel like doing anything, can't sleep without all the meds and then I only sleep a short time, positive anti-nuclear test. I feel like I am going crazy and now this rash is everywhere.

    Reply

    Ed on Mar, 5, 2013:

    Have your doctor check for Pheochromocytoma. I had all those symptoms and more. Pheo had grown around blood supply to kidney so it had to come out too. Much better since the surgery but I still have IBS, bipolar 2, low T, neuromuscular pain, one doctor wants to call it fibromyalgia

    Reply

    rmaran on Mar, 14, 2013:

    Have you had a sample taken of the sores to test them? One time I had a sore on my leg, they scraped a sample and performed a wide variety of tests on it. F 34 CA

    Reply

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Can you answer these questions (what is this?):

More questions for: Ibuprofen, Lyrica

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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