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Review: taking Lyrica and Ibuprofen together

Summary: drug interactions are reported among people who take Lyrica and Ibuprofen together.

This review analyzes the effectiveness and drug interactions between Lyrica and Ibuprofen. It is created by eHealthMe based on reports of 2,198 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Lyrica and Ibuprofen >>>

What are the drugs

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from 66,603 Lyrica users)

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from 61,637 Ibuprofen users)

On Feb, 11, 2015: 2,198 people who take Lyrica, Ibuprofen are studied

Lyrica, Ibuprofen outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effective10.00%
(1 of 10 people)
14.29%
(1 of 7 people)
40.00%
(2 of 5 people)
46.15%
(6 of 13 people)
50.00%
(6 of 12 people)
66.67%
(2 of 3 people)
0.00%
(0 of 1 people)
n/a
Ibuprofen is effective33.33%
(2 of 6 people)
16.67%
(1 of 6 people)
22.22%
(2 of 9 people)
16.67%
(1 of 6 people)
25.00%
(1 of 4 people)
28.57%
(2 of 7 people)
35.71%
(5 of 14 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessPainHyperkalaemiaDizzinessPainLymphocytosisMuscle TwitchingPain
Drug IneffectiveNauseaRenal Failure AcutePainDepressionChronic LeukaemiaMuscle SpasticityAnxiety
SomnolenceConfusional StateParalysisVision BlurredGallbladder Non-functioningLymphocytic LeukaemiaEuphoric MoodFatigue
NauseaVision BlurredConvulsionInsomniaBalance DisorderAggressionTearfulnessDizziness
Vision BlurredDizzinessApathySomnolenceWeight DecreasedPainTired EyesNausea
PainOedema PeripheralDisorientationVisual ImpairmentCholecystitis ChronicInfectionNauseaDrug Ineffective
Oedema PeripheralFatigueLoss Of ConsciousnessMyalgiaGastric PerforationInsomniaTremorDyspnoea
Feeling AbnormalMalaiseWithdrawal SyndromeGeneral Physical Health DeteriorationNerve InjuryIntentional OverdoseHeadacheVision Blurred
Dry MouthSomnolenceVision BlurredArthralgiaOptic Nerve DisorderHypothermiaVision BlurredBack Pain
Weight IncreasedHeadacheHaematemesisNauseaMental ImpairmentCardiac ArrestDepressionWeight Increased

Drug effectiveness by gender :

FemaleMale
Lyrica is effective39.02%
(16 of 41 people)
20.00%
(2 of 10 people)
Ibuprofen is effective30.95%
(13 of 42 people)
18.18%
(2 of 11 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyWeight Increased
DizzinessVision Blurred
NauseaDyspnoea
FatigueBack Pain
Drug IneffectiveAnxiety
DepressionFatigue
InjuryOsteonecrosis Of Jaw
Oedema PeripheralIntervertebral Disc Degeneration
DyspnoeaPyrexia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/a25.00%
(2 of 8 people)
8.00%
(2 of 25 people)
20.59%
(7 of 34 people)
27.78%
(5 of 18 people)
28.57%
(2 of 7 people)
Ibuprofen is effectiven/an/an/a25.00%
(2 of 8 people)
4.17%
(1 of 24 people)
22.86%
(8 of 35 people)
11.11%
(2 of 18 people)
25.00%
(2 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aParaesthesiaLoss Of ConsciousnessPainPainPainPain
VomitingHypoaesthesiaArthralgiaAnxietyHypoaesthesiaAnxiety
Heart Rate IncreasedPainNauseaDepressionAnxietyDyspnoea
Device Related InfectionConvulsionFatigueInjuryNauseaVision Blurred
PyrexiaInjuryDizzinessFatigueDepressionBack Pain
ChillsAbdominal PainIntervertebral Disc ProtrusionBack PainDrug IneffectiveOsteoarthritis
PainNauseaInjuryWeight IncreasedSomnolenceOedema Peripheral
Weight IncreasedPyrexiaHeadacheIntervertebral Disc ProtrusionDyspnoeaFall
Pain In ExtremityGallbladder DisorderAbdominal PainDizzinessDiarrhoeaDizziness
Staphylococcal BacteraemiaParalysisHodgkin's DiseaseSpinal OsteoarthritisPyrexiaNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Lyrica and Ibuprofen on

Do you take Lyrica and Ibuprofen?

You are not alone! Join a related mobile support group:
- support group for people who take Lyrica and Ibuprofen
- support group for people who take Ibuprofen
- support group for people who take Lyrica

Can you answer these questions (Ask a question):

  • Why is restoril showing poaitive in my urin when i never took this drug (2 answers)
    I have been ill for 15 years, taking Methadone all the while along with Soma and Hydrocodone for break thru pain. I now include Lyrica daily.I have had 2 back surgeries, one detailing rod and cage around L4 L5 in 2007. Most recent Nov 2013 at the Laser Spine Institute for spine decompression in that same area. Diagnosed w/ Arachnoiditis 15 yrs ago when working full time and since Methadone seems to be my only safe bet to take so that I can function. 4 years on Hizentra IVG home treatment every week. Lorazapam was prescribed for panic. Tried Diazapam more than 8-9 months ago, however that drug seems to back up in my system therefore I get no immediate relief but sort of a knock out sleep 8 hours later so we went back to Lorazapam. I am now unfortunately disabled, mostly homebound and 60 yrs old. Since this past August my urin specimen has come back positive for Restoril. This past month Restoril is still positive and described as habitual use. I am staring down a discharge from my physician who I care for, respect and admire, I never ever thought this would happen. We just took another test I offered to get another different Lab test she told me to wait so I am but its killing me. I never took a sleeping other than Unisom OTC in my Entire life. Never been prescribed Restoril, no offense but would never take it on top of what I already take and Lord knows how I would react to this drug. If I am awake all night that's just the way it is and I live with it. Why is this foreign drug showing up in my system? Please help. Thank you kindly, Louise
  • Does toviaz interact negatively with ibuproffen
    Male, 62 years old. Had a prostatectomy months ago (cancerous, 7 rating). One month after surgery, I started taking one 4 mg pill of Toviaz. Worked like magic with no side effects.
    Three weeks ago, I lost control again. The leakage was so bad in frequency that I had to go back to using pads. This lasted for 5 days before things gradually went back to "almost normal".
    The only difference in medication, food and drinks that I had in those 5 days is I used to take 2 ibuprofen pills (200 mg each) in the morning & 2 at night to deal with headache.
    Once I stopped taking the ibuprofen, things improved.
    Could what happened with me be the result of of interaction between Toviaz & Ibuproffen? I called Pfizer and the lady siad she does not have any information on this
  • Is bed wetting part of having syringomyelia
    i also use panadol osteo, mintec, apo-meloxicam. i have wetting the bed is was just now and then but it has started to become more frequent now, does any one else had this happen.
  • 8 year old boy has erratic heartbeat. started tamiflu last week. do i need to quit tamiflu? he had a 104.1 temp when we started treatments.
    Shortly after being dosed with Tamiflu this morning, he had a very erratic heartbeat. He is positive for influenza last Thursday and has been on Tamiflu since and Ibuprofen to manage fever (was up to 104.1 last week). Local clinic wants to see him. I don't feel like taking him there will solve anything. Its returned to normal within an hour of dosing with Tamiflu.
  • Does lyrica cause neutropenia and if it does, how long does it take to subside after stopping the drug?
    The patient is a 28 year old female who has been involved in a horrific car accident back in February 7th 2014. She had bilateral femural fracture along with fractured right tibia and fibula in addition to right humerus. However, to make it short, after treatment, the outcome was not acceptable with various complications. The patient is scheduled for another surgery, however, her CBC shows neutropenia (3.4).

More questions for: Ibuprofen, Lyrica

You may be interested at these reviews (Write a review):

  • The dangers off fluoridation
    I live in an area where the water has been fluoridated for approximately 55 years and have been treated for an underactive thyroid since 1978. I have also suffered from urge incontinence since 1967 and for 4 years have also had the symptoms of skeletal fluorosis although I have not been able to get the tests to confirm this. About 2 years ago I read about the dangers of fluoride and stopped using the tap water for drinking and cooking but still had to use it for bathing and still swam in the local pool. Also I have always drunk about 3 pints of tea a day. Recently it was found that there might be a problem with my kidneys so I stopped drinking tea and swimming. I had been going to the toilet 16/17 times a day but after about 5 weeks this was down to 7/8 times and the urgency was gone. Also I was given a follow up kidney function test after 6 weeks and that was normal. A few weeks later I was shopping in an area where the water is not fluoridated and risked having tea in a cafe there and the irritable bladder symptoms came back almost immediately and lasted for several weeks.
  • Ibuprofen and esophageal stricture
    After taking relatively high-doses of ibuprofen for many years, I developed an esophageal pain when swallowing large pills and experienced two unexplained events of esophageal spasm. A barium esophagram showed a stricture near the lower sphincter with a pencil-sized opening. Confirmed benign with a endoscopy and biopsy, it showed no gastric or duodenal ulcers from the ibuprofen, the stricture was expanded and I experience no discomfort now.
    I believe scarring of the esophagus was the result of taking ibuprofen often during the night with only a sip of water and then going back to bed. The ibuprofen dissolved in the water and by lying down immediately, the concentrated solution did not pass into my stomach but stayed in and irritated the lower esophagus for the rest of the night.
    To avoid future occurrences, the simple solution is to take ibuprofen with a full glass of water and avoid lying down for the next 30 minutes or so.
  • Lyrica is giving me nightmares
    I have fibromyalgia and a history of being allergic to or very sensitive to medications
    But Lyrica is really causing me some nightmares,sleepless nights, weight gain, headaches. I love that in the beginning I was able to get relief from fibromyalgia . It only made me really dizzy and disoriented on it. Now with theses symptoms I will definitely have to give it up. I can't seem to get any relief from this pain. I am so allergic to meds this is frustrating and miserable that meds make it worse.
  • Lyrica and doxylamine - not a good cocktail!
    I've been taking Lyrica 125mg total per day in 2x doses for 6 weeks, a few manageable side effects, (gaining weight and feeling dopey) I don't like it, but I recognise its ability to reduce @ 50% of the nerve pain and ability to help me function at work while I wait to see the surgeon.

    I took 50mg Doxylamine at night as a suggestion from a pharmacist to help sleep. Not a great idea! In the morning I was dulled, dopey. My speech was slurred, it made thinking very difficult and I couldn't drive safely. Felt spacey and stoned. For 48 hours!!! Even taking just 25mgs had long lasting side effects.
    I don't recommend this cocktail!
  • Arm pain on both sides from xarelto and levaquin
    Extreme pain in upper arms and forearms. Unable to lift anything of substance.

More reviews for: Ibuprofen, Lyrica

Comments from related studies:

  • From this study (4 months ago):

  • Elavil, 25mg @ night stopped an 11 month chronic headache after a head injury, I sustained 1 1/2 years ago.
    Additionally, Neurologist prescribed 100 mg Lyrica for chronic back/nerve pain from moderate/severe spinal injuries, sustained 20+ years earlier. (Crushed/cracked verabrae and 3 intervertebral disc bulges)
    I had been using Ibuprofen daily in moderate to heavy dosage for the last 20+ years. (800+ mg daily B/4 and then continually after recent head injury)
    I was advised to stop/reduce use of Motrin to 1/2 month or less. It is still the best pain relief but have reduced to PRN, perhaps 200 mg alternate days.
    Since treatment with Lyrica I've noticed reduced nerve pain and stopped using Elavil for sake of not feeling so "wrecked" in the mornings. I have also developed a severe sleep apnoea, treated unsuccessfully via CPAP device which is unbearable to use. I have subsequently suffered with depression/mood disorder for 20+ years and am currently un-treated for this long-standing vulnerability which came back with a vengence after the head-injury. I feel irregularity to my heart beat by the end of the day. I feel suicidal and violently angry.

    Reply

    Squidly on Oct, 25, 2014:

    Found this because I have similar symptoms- brain injury 2005, 12 herniated discs with osteophytes, migraines, seizures and the like. 1. The Motrin is an easy fix. Swap it out for Mobic (Meloxicam). I replaced 1600mg/day for 12mg Mobic and it's easier on the stomach. 2. The Evril and Lyrica taken together causes dizziness. Get a different antidepressant or swap the Lyrica for Neurontin (gabapentin). I had to because I couldn't stand up without passing out. 3. The B/4 I'm stumped on as its not approved for use in the United States but I know it can help with seizures but a friend of mine tells me it makes her sick. 4. Waking up at night. No where in your medication is a pain reliever or muscle relaxer for your back. An anti-inflammatory like Ibuprofen will not cut it when you lay on it. Get both, whether low level like Flexoril and Hydrocodone, or if needed Soma and Methadone. Something is needed to relieve the pain on your back which, can also cause the headaches. 5. Anger - A head injury can cause an inability to control ones emotions, even reacting inappropriately (wrong emotion or too much emotion) in circumstances. If this is the case, treat yourself as a toddler and try to relearn how to react (counting to 10, timeouts) and informing loved ones this is going on. Another thing is that you may have Marijuana rage. This is something I thought was untrue until my brother-in-law stabbed his wife's hand with a fork for being near him while smoking with his buddies. Just as there are angry drunks, there are angry pot heads and TBI can change how you react.

    Reply

    dutchgirlsamm on Aug, 30, 2014:

    Lyrics is known to cause suicidal thoughts and aggression...its called an adverse reaction.

    Reply

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Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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