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Review: Lyrica and Ibuprofen

This review analyzes the effectiveness and drug interactions between Lyrica and Ibuprofen. It is created by eHealthMe based on reports of 2,197 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Lyrica and Ibuprofen >>>

What are the drugs

Lyrica (what 66,503 Lyrica users reported?) has active ingredients of pregabalin. It is used in fibromyalgia.

Ibuprofen (what 61,542 Ibuprofen users reported?) has active ingredients of ibuprofen. It is used in pain.

On Sep, 10, 2014: 2,197 people who take Lyrica, Ibuprofen are studied

Lyrica, Ibuprofen outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effective10.00%
(1 of 10 people)
14.29%
(1 of 7 people)
40.00%
(2 of 5 people)
46.15%
(6 of 13 people)
50.00%
(6 of 12 people)
66.67%
(2 of 3 people)
0.00%
(0 of 1 people)
n/a
Ibuprofen is effective33.33%
(2 of 6 people)
16.67%
(1 of 6 people)
22.22%
(2 of 9 people)
16.67%
(1 of 6 people)
25.00%
(1 of 4 people)
28.57%
(2 of 7 people)
35.71%
(5 of 14 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessPainHyperkalaemiaDizzinessPainLymphocytosisMuscle TwitchingPain
Drug IneffectiveNauseaRenal Failure AcutePainDepressionChronic LeukaemiaMuscle SpasticityAnxiety
SomnolenceConfusional StateParalysisVision BlurredGallbladder Non-functioningLymphocytic LeukaemiaEuphoric MoodFatigue
NauseaVision BlurredConvulsionInsomniaBalance DisorderAggressionTearfulnessDizziness
Vision BlurredDizzinessApathySomnolenceWeight DecreasedPainTired EyesNausea
PainOedema PeripheralDisorientationVisual ImpairmentCholecystitis ChronicInfectionNauseaDrug Ineffective
Oedema PeripheralFatigueLoss Of ConsciousnessMyalgiaGastric PerforationInsomniaTremorDyspnoea
Feeling AbnormalMalaiseWithdrawal SyndromeGeneral Physical Health DeteriorationNerve InjuryIntentional OverdoseHeadacheVision Blurred
Dry MouthSomnolenceVision BlurredArthralgiaOptic Nerve DisorderHypothermiaVision BlurredBack Pain
Weight IncreasedHeadacheHaematemesisNauseaMental ImpairmentCardiac ArrestDepressionWeight Increased

Drug effectiveness by gender :

FemaleMale
Lyrica is effective39.02%
(16 of 41 people)
20.00%
(2 of 10 people)
Ibuprofen is effective30.95%
(13 of 42 people)
18.18%
(2 of 11 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyWeight Increased
DizzinessVision Blurred
NauseaDyspnoea
FatigueBack Pain
Drug IneffectiveAnxiety
DepressionFatigue
InjuryOsteonecrosis Of Jaw
Oedema PeripheralIntervertebral Disc Degeneration
DyspnoeaPyrexia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/a25.00%
(2 of 8 people)
8.00%
(2 of 25 people)
20.59%
(7 of 34 people)
27.78%
(5 of 18 people)
28.57%
(2 of 7 people)
Ibuprofen is effectiven/an/an/a25.00%
(2 of 8 people)
4.17%
(1 of 24 people)
22.86%
(8 of 35 people)
11.11%
(2 of 18 people)
25.00%
(2 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aParaesthesiaLoss Of ConsciousnessPainPainPainPain
VomitingHypoaesthesiaArthralgiaAnxietyHypoaesthesiaAnxiety
Heart Rate IncreasedPainNauseaDepressionAnxietyDyspnoea
Device Related InfectionConvulsionFatigueInjuryNauseaVision Blurred
PyrexiaInjuryDizzinessFatigueDepressionBack Pain
ChillsAbdominal PainIntervertebral Disc ProtrusionBack PainDrug IneffectiveOsteoarthritis
PainNauseaInjuryWeight IncreasedSomnolenceOedema Peripheral
Weight IncreasedPyrexiaHeadacheIntervertebral Disc ProtrusionDyspnoeaFall
Pain In ExtremityGallbladder DisorderAbdominal PainDizzinessDiarrhoeaDizziness
Staphylococcal BacteraemiaParalysisHodgkin's DiseaseSpinal OsteoarthritisPyrexiaNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lyrica and Ibuprofen?

Get connected! Join a mobile support group:
- group for people who take Lyrica and Ibuprofen
- group for people who take Ibuprofen
- group for people who take Lyrica

Comments from related studies:

  • From this study (2 weeks ago):

  • Elavil, 25mg @ night stopped an 11 month chronic headache after a head injury, I sustained 1 1/2 years ago.
    Additionally, Neurologist prescribed 100 mg Lyrica for chronic back/nerve pain from moderate/severe spinal injuries, sustained 20+ years earlier. (Crushed/cracked verabrae and 3 intervertebral disc bulges)
    I had been using Ibuprofen daily in moderate to heavy dosage for the last 20+ years. (800+ mg daily B/4 and then continually after recent head injury)
    I was advised to stop/reduce use of Motrin to 1/2 month or less. It is still the best pain relief but have reduced to PRN, perhaps 200 mg alternate days.
    Since treatment with Lyrica I've noticed reduced nerve pain and stopped using Elavil for sake of not feeling so "wrecked" in the mornings. I have also developed a severe sleep apnoea, treated unsuccessfully via CPAP device which is unbearable to use. I have subsequently suffered with depression/mood disorder for 20+ years and am currently un-treated for this long-standing vulnerability which came back with a vengence after the head-injury. I feel irregularity to my heart beat by the end of the day. I feel suicidal and violently angry.

    Reply

    dutchgirlsamm on Aug, 30, 2014:

    Lyrics is known to cause suicidal thoughts and aggression...its called an adverse reaction.

    Reply

  • From this study (7 months ago):

  • at first I lost hearing on my left ear for several weeks with pain, eventually hearing came back. Then it occurred on my right, eventually recovered hearing. But both ears had extreme pressure and now tubes were inserted. Left ear recovered from pressure but continue to have pain. Right ear sounds as if I have water inside and I hear myself as if I'm talking inside a closet or enclosed room, only in my right ear. But both ears hurt like if my ears are being pulled downward.

    Reply

  • From this study (1 year ago):

  • Doc has recommended small dose Lexapro for anxiety (I am 82 yrs old) and I am concerned that this will cause some constipation and/or fogginess that will make me unsteady on my feet

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Had a bloody ejaculate twice lately. only blood. can it be related to cialis and/or ibuprofen?
    last two ejaculations a week apart resulted in all blood ejaculate. Dark old looking blood, not bright red & fresh. No semen. Gonna tell my doctor soon. What should I be concerned about. Could it be ralated to ibuprofen or cialis usage? i dont have any known predisposing conditions.

  • Can droopy eyelid be caused by a bump and/or pregabalin?
    Had a bad bump on my forehead a couple of weeks ago and my whole face went black. Mostly better now but Im let with a badly drooping eyelid (right) which the doctors tell me will go away. No sign of that at the moment but Ive read that pregabalin (which I take in small doses, can cause this. It ...

  • Is anyone else with ms having problems getting off of lyrica?
    I am on 1.5 mg clonazepam and I take Betaseron injectables for my MS. I take 50 mg of Ellaville and one Prilosec that's it. I was on Lyrica for about three months and am having a horrible time trying to come down off of it. I would really like to know if anyone has tried the Lyrica oral suspension. ...

More questions for: Ibuprofen, Lyrica

You may be interested at these reviews (what is this?):

  • Lyrica varied widely
    I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the dru ...

  • Lyrica photosensitivity
    Spent several hours outside in partly sunny conditions on Sat. Swelling started a little on Sun. But by Monday my face was ver swollen and red with small bumps most noticeable across the cheeks, nose and area of the forehead where bangs did not cover. I have only been using for (6) months. Un ...

  • Wheezing stopped after topamax sessesion
    Wheezing noted by primary physician in this non-smoker. Stopped Topamax per doctor's instruction. 48 hours later was examined by physician and noted that wheezing stopped.

More reviews for: Ibuprofen, Lyrica

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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