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Related topic: Keppra, Lyrica

Review: Lyrica and Keppra

This review analyzes the effectiveness and drug interactions between Lyrica and Keppra. It is created by eHealthMe based on 678 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 12, 2014: 678 people who take Lyrica, Keppra are studied

Lyrica, Keppra outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Keppra (levetiracetam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effectiven/a50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/a
Keppra is effective100.00%
(1 of 1 people)
66.67%
(2 of 3 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
40.00%
(2 of 5 people)
0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/a

Drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Convulsion
(8 reports)

Somnolence
(7 reports)

Feeling Abnormal
(7 reports)

Dizziness
(6 reports)

Balance Disorder
(5 reports)

Gait Disturbance
(4 reports)

Nausea
(4 reports)

Suicide Attempt
(4 reports)

Disturbance In Attention
(4 reports)

Asthenia
(4 reports)

Convulsion
(6 reports)

Dizziness
(5 reports)

Insomnia
(4 reports)

Pruritus
(4 reports)

Depression
(4 reports)

T-cell Lymphoma
(3 reports)

Suicidal Ideation
(3 reports)

Epilepsy
(3 reports)

Headache
(3 reports)

Rash
(3 reports)

Convulsion
(3 reports)

Disturbance In Attention
(3 reports)

Eye Irritation
(2 reports)

Dry Mouth
(2 reports)

Low Density Lipoprotein Increased
(2 reports)

Simple Partial Seizures
(2 reports)

Nervous System Disorder
(2 reports)

Ataxia
(2 reports)

Confusional State
(2 reports)

Feeling Abnormal
(2 reports)

Fatigue
(4 reports)

Convulsion
(3 reports)

Depression Suicidal
(3 reports)

Depression
(2 reports)

Aura
(2 reports)

Sedation
(2 reports)

Paranoia
(1 report)

Respiratory Tract Congestion
(1 report)

Anxiety
(1 report)

Coordination Abnormal
(1 report)

Convulsion
(4 reports)

Adrenal Insufficiency
(2 reports)

Insomnia
(2 reports)

Visual Acuity Reduced
(2 reports)

Optic Atrophy
(2 reports)

Balance Disorder
(2 reports)

Headaches
(1 report)

Loss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And Numbness
(1 report)

Drug Ineffective
(1 report)

Visual Field Defect
(1 report)

Seizures
(1 report)

Pulmonary Venous Thrombosis
(1 report)

Brain Injury
(1 report)

Supraventricular Tachycardia
(1 report)

Kidney Stones
(1 report)

Cough
(1 report)

Convulsion
(132 reports)

Fatigue
(53 reports)

Somnolence
(39 reports)

Dizziness
(38 reports)

Drug Ineffective
(37 reports)

Fall
(34 reports)

Weight Increased
(31 reports)

Memory Impairment
(30 reports)

Epilepsy
(29 reports)

Grand Mal Convulsion
(28 reports)

Drug effectiveness by gender :

FemaleMale
Lyrica is effective25.00%
(3 of 12 people)
66.67%
(2 of 3 people)
Keppra is effective46.15%
(6 of 13 people)
66.67%
(2 of 3 people)

Drug interactions by gender * :

FemaleMale
Convulsion
(109 reports)

Fatigue
(52 reports)

Dizziness
(45 reports)

Somnolence
(38 reports)

Weight Increased
(33 reports)

Drug Ineffective
(31 reports)

Vision Blurred
(30 reports)

Memory Impairment
(25 reports)

Fall
(25 reports)

Epilepsy
(25 reports)

Convulsion
(43 reports)

Somnolence
(14 reports)

Fatigue
(13 reports)

Aggression
(13 reports)

Drug Ineffective
(11 reports)

Dizziness
(10 reports)

Oedema Peripheral
(9 reports)

Confusional State
(9 reports)

Gait Disturbance
(9 reports)

Grand Mal Convulsion
(9 reports)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
11.11%
(2 of 18 people)
11.76%
(2 of 17 people)
0.00%
(0 of 1 people)
Keppra is effectiven/an/an/a0.00%
(0 of 3 people)
60.00%
(3 of 5 people)
10.53%
(2 of 19 people)
17.65%
(3 of 17 people)
0.00%
(0 of 1 people)

Drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aMetabolic Acidosis
(3 reports)

Calculus Urinary
(1 report)

Convulsion
(1 report)

Haemodynamic Instability
(1 report)

Drug Ineffective
(1 report)

Acidosis Hyperchloraemic
(1 report)

Convulsion
(5 reports)

Back Pain
(3 reports)

Cervical Vertebral Fracture
(3 reports)

Aggression
(2 reports)

Psychotic Disorder
(2 reports)

Memory Impairment
(2 reports)

Abnormal Behaviour
(2 reports)

Drug Effect Decreased
(2 reports)

Paranoia
(2 reports)

Grand Mal Convulsion
(2 reports)

Convulsion
(18 reports)

Pyrexia
(6 reports)

Drug Exposure During Pregnancy
(5 reports)

Epilepsy
(5 reports)

Pneumonia
(4 reports)

Sedation
(4 reports)

Brain Injury
(4 reports)

Poisoning
(4 reports)

Confusional State
(4 reports)

Dizziness
(4 reports)

Convulsion
(19 reports)

Weight Increased
(12 reports)

Dizziness
(11 reports)

Cardiac Arrest
(8 reports)

Vision Blurred
(7 reports)

Fatigue
(6 reports)

Memory Impairment
(6 reports)

Tremor
(5 reports)

Optic Atrophy
(5 reports)

Loss Of Consciousness
(5 reports)

Convulsion
(34 reports)

Somnolence
(17 reports)

Ataxia
(17 reports)

Fatigue
(13 reports)

Drug Ineffective
(13 reports)

Tremor
(12 reports)

Immune Reconstitution Syndrome
(12 reports)

Progressive Multifocal Leukoencephalopathy
(12 reports)

Back Pain
(11 reports)

Dizziness
(11 reports)

Convulsion
(28 reports)

Epilepsy
(19 reports)

Fatigue
(14 reports)

Grand Mal Convulsion
(10 reports)

Drug Ineffective
(9 reports)

Weight Increased
(9 reports)

Somnolence
(9 reports)

Fall
(9 reports)

Hypoaesthesia
(8 reports)

Dyspnoea
(8 reports)

Convulsion
(20 reports)

Fatigue
(14 reports)

Grand Mal Convulsion
(10 reports)

Hallucination
(10 reports)

Pancreatitis
(9 reports)

Drug Ineffective
(8 reports)

Abdominal Distension
(8 reports)

Dysuria
(8 reports)

Confusional State
(8 reports)

Somnolence
(8 reports)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (7 months ago):

  • I am trying to find out if taking Lyrica has caused me to develop a chronic cough or if it is just allergies

    Reply

  • From this study (2 years ago):

  • Over past 2 months have been increasing Keppra to present dose of 2000 miligrams daily. Low Sodium level detected 2 weeks ago, at 130. Dilantin is 600 miligrams daily.

    Reply

  • From this study (2 years ago):

  • i am on multiple meds after total removal of para and thyroid glands

    Reply

    june turner 256557 9964 on Apr, 17, 2012:

    i still have seizures most everday, pain from fibromyalgia, numbness in left arm hand ,leg and shoulder, need help on diagnosis and help. i have reactions to light ,heat, cold,sound, and numerous others due to this...

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Can trileptal cause a-fib
    I had an ablation. I got irregular hr on lyrica for neuropathy peripheral.md changed to oxcarbazepine. do these drugs cause a-fib. what is best pain med that does not cause a-fib or tachycardia.cymbalta,paxil Prozac caused atrial tachy and a-fib.?

  • Can i take ibuprophen while i'm taking lyrica
    I'm taking Lyrica for shingles. Although it has greatly helped with the pain, I still have considerable itchiness and pain upon touching the affected area. Can I take ibuprophen along with the lyrica? Any suggestions for the itch?

  • Is safe keppra for g6pd?
    my baby is 3 yrs old g6pd and cerebral palsy condition,, she suffering seizures

More questions for: Keppra, Lyrica

You may be interested at these reviews (what is this?):

  • Lyrica caused my kidneys to shut down
    I was on Lyrica for 6 weeks and it almost killed me. I was so weak at the end that my daughter had to help me get out of bed go to the bathroom. I gained 22 lbs in 10 days. I gained over 40 lbs in 6 weeks. My ankles and feet were so swollen that the skin was starting to break open. I was in and out ...

  • Health issues and struggles
    I have numerous health issues. Some I've lived with not realizing they were there. Others are caused by meds I've taken in the past or am still using now. Lupus is the most recent and biggest trouble I have right now. It is caused by the one drug that finally gave me control of my seizures Some o ...

  • Sleepwalking while on lyrica
    I have never had issues with sleepwalking until taking Lyrica. I have had some terrifying experiences like walking up in a hotel lobby in my short nightie. After several episodes, I stopped taking lyrica and stopped sleepwalking. Recently my doctor put me back on this drug and the first night I took ...

More reviews for: Keppra, Lyrica

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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