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Review: Lyrica and Keppra

This review analyzes the effectiveness and drug interactions between Lyrica and Keppra. It is created by eHealthMe based on reports of 680 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Lyrica and Keppra >>>

What are the drugs

Lyrica (latest outcomes from 66,459 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

Keppra (latest outcomes from 21,166 users) has active ingredients of levetiracetam. It is often used in epilepsy.

On Jul, 15, 2014: 680 people who take Lyrica, Keppra are studied

Lyrica, Keppra outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Keppra (levetiracetam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effectiven/a50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/a
Keppra is effective100.00%
(1 of 1 people)
66.67%
(2 of 3 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
40.00%
(2 of 5 people)
0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConvulsionConvulsionConvulsionFatigueConvulsionSeizuresCoughConvulsion
SomnolenceDizzinessDisturbance In AttentionConvulsionAdrenal InsufficiencyPulmonary Venous ThrombosisFatigue
Feeling AbnormalInsomniaEye IrritationDepression SuicidalInsomniaBrain InjuryDizziness
DizzinessPruritusDry MouthDepressionVisual Acuity ReducedSupraventricular TachycardiaSomnolence
Balance DisorderDepressionLow Density Lipoprotein IncreasedAuraOptic AtrophyKidney StonesDrug Ineffective
Gait DisturbanceT-cell LymphomaSimple Partial SeizuresSedationBalance DisorderWeight Increased
NauseaSuicidal IdeationNervous System DisorderParanoiaHeadachesFall
Suicide AttemptEpilepsyAtaxiaRespiratory Tract CongestionLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessGrand Mal Convulsion
Disturbance In AttentionHeadacheConfusional StateAnxietyDrug IneffectiveEpilepsy
AstheniaRashCondition AggravatedCoordination AbnormalVisual Field DefectVision Blurred

Drug effectiveness by gender :

FemaleMale
Lyrica is effective25.00%
(3 of 12 people)
66.67%
(2 of 3 people)
Keppra is effective46.15%
(6 of 13 people)
66.67%
(2 of 3 people)

Most common drug interactions by gender * :

FemaleMale
ConvulsionConvulsion
FatigueSomnolence
DizzinessFatigue
SomnolenceAggression
Weight IncreasedDrug Ineffective
Drug IneffectiveDizziness
Vision BlurredOedema Peripheral
Memory ImpairmentConfusional State
FallGait Disturbance
EpilepsyGrand Mal Convulsion

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
11.11%
(2 of 18 people)
11.76%
(2 of 17 people)
0.00%
(0 of 1 people)
Keppra is effectiven/an/an/a0.00%
(0 of 3 people)
60.00%
(3 of 5 people)
10.53%
(2 of 19 people)
17.65%
(3 of 17 people)
0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aMetabolic AcidosisConvulsionConvulsionConvulsionConvulsionConvulsionConvulsion
Calculus UrinaryBack PainCondition AggravatedWeight IncreasedSomnolenceEpilepsyFatigue
ConvulsionCervical Vertebral FracturePyrexiaDizzinessAtaxiaFatigueGrand Mal Convulsion
Haemodynamic InstabilityAggressionDrug Exposure During PregnancyCardiac ArrestFatigueGrand Mal ConvulsionHallucination
Drug IneffectivePsychotic DisorderEpilepsyVision BlurredDrug IneffectiveFallPancreatitis
Acidosis HyperchloraemicMemory ImpairmentPneumoniaMemory ImpairmentTremorSomnolenceDrug Ineffective
Abnormal BehaviourSedationFatigueImmune Reconstitution SyndromeWeight IncreasedAbdominal Distension
Drug Effect DecreasedBrain InjuryLoss Of ConsciousnessProgressive Multifocal LeukoencephalopathyDrug IneffectiveDysuria
ParanoiaPoisoningFallBack PainMemory ImpairmentConfusional State
Grand Mal ConvulsionConfusional StateOptic AtrophyDizzinessDyspnoeaSomnolence

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Comments from related studies:

  • From this study (10 months ago):

  • I am trying to find out if taking Lyrica has caused me to develop a chronic cough or if it is just allergies

    Reply

  • From this study (2 years ago):

  • Over past 2 months have been increasing Keppra to present dose of 2000 miligrams daily. Low Sodium level detected 2 weeks ago, at 130. Dilantin is 600 miligrams daily.

    Reply

  • From this study (2 years ago):

  • i am on multiple meds after total removal of para and thyroid glands

    Reply

    june turner 256557 9964 on Apr, 17, 2012:

    i still have seizures most everday, pain from fibromyalgia, numbness in left arm hand ,leg and shoulder, need help on diagnosis and help. i have reactions to light ,heat, cold,sound, and numerous others due to this...

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Can droopy eyelid be caused by a bump and/or pregabalin?
    Had a bad bump on my forehead a couple of weeks ago and my whole face went black. Mostly better now but Im let with a badly drooping eyelid (right) which the doctors tell me will go away. No sign of that at the moment but Ive read that pregabalin (which I take in small doses, can cause this. It ...

  • Is anyone else with ms having problems getting off of lyrica?
    I am on 1.5 mg clonazepam and I take Betaseron injectables for my MS. I take 50 mg of Ellaville and one Prilosec that's it. I was on Lyrica for about three months and am having a horrible time trying to come down off of it. I would really like to know if anyone has tried the Lyrica oral suspension. ...

  • Can a person with hear problems that took lyrica have sudden death
    my husband took lyrica in dec 2007 swelled up the md prescribed more and he died suddenly on March 17 2008 i wrote to pfziers legal department for answers as they directed me and i never heard from them.

More questions for: Keppra, Lyrica

You may be interested at these reviews (what is this?):

  • Review: could lyrica cause intracranial pressure increased?
    One dose (75mg) caused severe head pain (increased intracranial pressure) and nausea.

  • Chest pain from keppra xr
    after 6 years developed right side pain near kidneys a few days a month . 2 inside of eye lid red dry eyes took keppra 7 years . started to have chest pain left side .after a month of pain . that would start 3 to 6 hours after taking keppra . would have pain thru the day stopped keppr ...

  • Lyrica caused my kidneys to shut down
    I was on Lyrica for 6 weeks and it almost killed me. I was so weak at the end that my daughter had to help me get out of bed go to the bathroom. I gained 22 lbs in 10 days. I gained over 40 lbs in 6 weeks. My ankles and feet were so swollen that the skin was starting to break open. I was in and out ...

More reviews for: Keppra, Lyrica

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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