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Review: taking Lyrica and Keppra together

Summary: drug interactions are reported among people who take Lyrica and Keppra together.

This review analyzes the effectiveness and drug interactions between Lyrica and Keppra. It is created by eHealthMe based on reports of 680 people who take the same drugs from FDA and social media, and is updated regularly.

 

You are not alone: join a support group for people who take Lyrica and Keppra >>>

On Apr, 2, 2015: 680 people who take Lyrica, Keppra are studied

Lyrica, Keppra outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Keppra (levetiracetam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effectiven/a50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/a
Keppra is effective100.00%
(1 of 1 people)
66.67%
(2 of 3 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
40.00%
(2 of 5 people)
0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/a

Drug effectiveness by gender :

FemaleMale
Lyrica is effective25.00%
(3 of 12 people)
66.67%
(2 of 3 people)
Keppra is effective46.15%
(6 of 13 people)
66.67%
(2 of 3 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lyrica is effectiven/an/an/a0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
11.11%
(2 of 18 people)
11.76%
(2 of 17 people)
0.00%
(0 of 1 people)
Keppra is effectiven/an/an/a0.00%
(0 of 3 people)
60.00%
(3 of 5 people)
10.53%
(2 of 19 people)
17.65%
(3 of 17 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConvulsionConvulsionConvulsionFatigueConvulsionSeizuresCoughConvulsion
SomnolenceDizzinessDisturbance In AttentionConvulsionAdrenal InsufficiencyPulmonary Venous ThrombosisFatigue
Feeling AbnormalInsomniaEye IrritationDepression SuicidalInsomniaBrain InjuryDizziness
DizzinessPruritusDry MouthDepressionVisual Acuity ReducedSupraventricular TachycardiaSomnolence
Balance DisorderDepressionLow Density Lipoprotein IncreasedAuraOptic AtrophyKidney StonesDrug Ineffective
Gait DisturbanceT-cell LymphomaSimple Partial SeizuresSedationBalance DisorderWeight Increased
NauseaSuicidal IdeationNervous System DisorderParanoiaHeadachesFall
Suicide AttemptEpilepsyAtaxiaRespiratory Tract CongestionLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessGrand Mal Convulsion
Disturbance In AttentionHeadacheConfusional StateAnxietyDrug IneffectiveEpilepsy
AstheniaRashCondition AggravatedCoordination AbnormalVisual Field DefectVision Blurred

Most common drug interactions by gender * :

FemaleMale
ConvulsionConvulsion
FatigueSomnolence
DizzinessFatigue
SomnolenceAggression
Weight IncreasedDrug Ineffective
Drug IneffectiveDizziness
Vision BlurredOedema Peripheral
Memory ImpairmentConfusional State
FallGait Disturbance
EpilepsyGrand Mal Convulsion

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aMetabolic AcidosisConvulsionConvulsionConvulsionConvulsionConvulsionConvulsion
Calculus UrinaryBack PainCondition AggravatedWeight IncreasedSomnolenceEpilepsyFatigue
ConvulsionCervical Vertebral FracturePyrexiaDizzinessAtaxiaFatigueGrand Mal Convulsion
Haemodynamic InstabilityAggressionDrug Exposure During PregnancyCardiac ArrestFatigueGrand Mal ConvulsionHallucination
Drug IneffectivePsychotic DisorderEpilepsyVision BlurredDrug IneffectiveFallPancreatitis
Acidosis HyperchloraemicMemory ImpairmentPneumoniaMemory ImpairmentTremorSomnolenceDrug Ineffective
Abnormal BehaviourSedationFatigueImmune Reconstitution SyndromeWeight IncreasedAbdominal Distension
Drug Effect DecreasedBrain InjuryLoss Of ConsciousnessProgressive Multifocal LeukoencephalopathyDrug IneffectiveDysuria
ParanoiaPoisoningFallBack PainMemory ImpairmentConfusional State
Grand Mal ConvulsionConfusional StateOptic AtrophyDizzinessDyspnoeaSomnolence

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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You are not alone! Join a related support group:
- support group for people who take Keppra
- support group for people who take Lyrica

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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