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Review: Lyrica and Mirtazapine

This review analyzes the effectiveness and drug interactions between Lyrica and Mirtazapine. It is created by eHealthMe based on reports of 902 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Lyrica and Mirtazapine >>>

What are the drugs

Lyrica (latest outcomes from 66,519 users) has active ingredients of pregabalin. It is often used in fibromyalgia.

Mirtazapine (latest outcomes from 17,919 users) has active ingredients of mirtazapine. It is often used in depression.

On Oct, 29, 2014: 902 people who take Lyrica, Mirtazapine are studied

Lyrica, Mirtazapine outcomes

Drug combinations in study:
- Lyrica (pregabalin)
- Mirtazapine (mirtazapine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lyrica is effective60.00%
(3 of 5 people)
(2 of 6 people)
(2 of 7 people)
(0 of 1 people)
(0 of 5 people)
(1 of 3 people)
Mirtazapine is effective0.00%
(0 of 2 people)
(4 of 9 people)
(2 of 6 people)
(0 of 3 people)
(3 of 4 people)
(1 of 3 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyskinesiaWeight IncreasedWeight IncreasedLower Respiratory Tract InfectionDiarrhoeaRestless Legs Syndromen/aPain
DizzinessOedema PeripheralCognitive DisorderInfluenza Like IllnessChillsWeight DecreasedAnxiety
Grand Mal ConvulsionPolypAstheniaWeight IncreasedFatigueBack PainDyspnoea
DystoniaDyspnoeaDehydrationUrinary Tract InfectionVomitingLimb DiscomfortOedema Peripheral
ConvulsionSuicidal IdeationVomitingFractureColitisParaesthesiaNausea
Oculogyric CrisisSwelling FaceDrug IneffectiveHallucinationBalance DisorderMusculoskeletal PainFatigue
TremorLocal SwellingDyspnoeaFallSlow SpeechVomitingPain In Extremity
AnxietyHepatitisSuicidal IdeationSomnolenceDizzinessVitamin D DecreasedPyrexia
Feeling AbnormalHeadacheRenal Failure AcuteHeart Rate IncreasedDehydrationAbdominal PainBack Pain
Oedema PeripheralMalaiseDepressionBalance DisorderMalaisePancytopeniaDizziness

Drug effectiveness by gender :

Lyrica is effective25.00%
(4 of 16 people)
(4 of 11 people)
Mirtazapine is effective29.41%
(5 of 17 people)
(6 of 12 people)

Most common drug interactions by gender * :

Oedema PeripheralNausea
Back PainPyrexia
Pain In ExtremityDyspnoea
NauseaDecreased Appetite

Drug effectiveness by age :

Lyrica is effectiven/an/an/a10.00%
(1 of 10 people)
(2 of 11 people)
(2 of 9 people)
(2 of 13 people)
(1 of 5 people)
Mirtazapine is effectiven/an/an/a30.00%
(3 of 10 people)
(4 of 11 people)
(2 of 13 people)
(1 of 14 people)
(1 of 5 people)

Most common drug interactions by age * :

n/an/aHypokalaemiaGrand Mal ConvulsionGait DisturbancePainDyspnoeaDizziness
Suicide AttemptDyskinesiaWeight IncreasedCompleted SuicidePainNausea
HypocalcaemiaOculogyric CrisisNauseaDyspnoeaAnxietyPain
Extrapyramidal DisorderDystoniaAtaxiaOedema PeripheralBack PainAnxiety
Multiple Drug OverdoseConvulsionEnuresisDrug IneffectiveOedema PeripheralPain In Extremity
VomitingPyrexiaMuscle TwitchingDepressionStaphylococcal InfectionDyspnoea
Hepatic Enzyme IncreasedSuicidal IdeationAnxietyWeight IncreasedUrinary Tract InfectionArthralgia
MydriasisNauseaPainAnxietyIntervertebral Disc ProtrusionDiarrhoea
DyskinesiaChest DiscomfortDysarthriaAstheniaHypoaesthesiaFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lyrica and Mirtazapine?

Get connected! Join a related mobile support group:
- support group for people who take Lyrica and Mirtazapine
- support group for people who take Lyrica
- support group for people who take Mirtazapine

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Complete drug side effects:

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Mirtazapine (mirtazapine) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies:

More related studies for: Lyrica, Mirtazapine

Recent related drug comparison:

More related comparisons for: Lyrica, Mirtazapine

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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