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Review: Macrobid and Methotrexate





Summary: drug interactions are reported among people who take Macrobid and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Macrobid and Methotrexate. It is created by eHealthMe based on reports of 156 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Macrobid and Methotrexate >>>

What are the drugs

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. (latest outcomes from Macrobid 3,446 users)

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

On Nov, 25, 2014: 156 people who take Macrobid, Methotrexate are studied

Macrobid, Methotrexate outcomes

Drug combinations in study:
- Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Macrobid is effective0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Methotrexate is effectiven/an/an/an/a50.00%
(1 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Platelet DisorderMouth UlcerationPancreatitis AcutePulmonary FibrosisCardiac Arrestn/aMeningitis CryptococcalArthralgia
Renal Failure AcuteEye Infection NosOedematous PancreatitisRespiratory FailureSepsisNasal CongestionPain
NeutropeniaPharyngolaryngeal PainUrinary Tract InfectionGastroenteritisCoughDyspnoea
Mucosal InflammationUrinary Tract Disorder NosPneumoniaPyrexiaArthralgiaUrinary Tract Infection
InfectionDyspnoeaPneumonitisSudden DeathRigorsPyrexia
Pancreatitis AcuteHerpes ZosterHypoxiaUrinary Tract Infection EnterococcalRespiratory Tract CongestionTransient Ischaemic Attack
Oedematous PancreatitisCondition AggravatedChest DiscomfortWhite Blood Cell Count DecreasedWhite Blood Cells Urine PositiveChest Pain
PancytopeniaChest PainComaGeneral Physical Health DeteriorationHyperhidrosisOedema Peripheral
ShinglesAbdominal Pain UpperDizzinessEscherichia InfectionWhite Blood Cell Count IncreasedPneumonia
Peripheral SwellingBronchopneumoniaEnterococcal InfectionBlood Urine PresentGeneral Physical Health Deterioration

Drug effectiveness by gender :

FemaleMale
Macrobid is effective0.00%
(0 of 2 people)
n/a
Methotrexate is effective50.00%
(1 of 2 people)
n/a

Most common drug interactions by gender * :

FemaleMale
ArthralgiaOral Pain
PainDyspnoea
Transient Ischaemic AttackHerpes Zoster
Chest PainPneumonia
DyspnoeaCataract Nec
Urinary Tract InfectionCough
PyrexiaMalaise
General Physical Health DeteriorationPneumonia Nos
AnxietyMyocardial Infarction
Oedema PeripheralNeutropenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Macrobid is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
n/a
Methotrexate is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 3 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPyrexian/aOedematous PancreatitisPainArthralgiaChest PainArthralgia
GastroenteritisPancreatitis AcuteDiscomfortMeningitis CryptococcalHerpes ZosterUrinary Tract Infection
Cardiac ArrestFatigueDecreased InterestDyspnoea NosOedema Peripheral
SepsisHyperhidrosisInsomniaDyspnoeaPain
Sudden DeathRestlessnessMetastases To BoneCardiovascular Disorder NosTransient Ischaemic Attack
Haemoglobin DecreasedPelvic Venous ThrombosisBone DisorderPharyngolaryngeal PainGeneral Physical Health Deterioration
C-reactive Protein IncreasedDiarrhoeaPurulent DischargeCoughChest Pain
Joint SwellingFeeling ColdColon NeoplasmDiabetes MellitusDyspnoea
Blood Phosphorus IncreasedPremature LabourPancreatic NeoplasmDrug IneffectiveNausea
Culture Urine PositivePremature Rupture Of MembranesAnimal BiteFallFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Macrobid and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Macrobid and Methotrexate
- support group for people who take Macrobid
- support group for people who take Methotrexate

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks
  • Can i take marijuana while taking gilenya
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate
  • Do i need to temporarily stop taking my enbrel and methotrexate (that i take every week) while i am on azithromycin for severe cold symptoms? (1 answer)
    i have RA and take Enbrel and methotrexate every week. i am currently taking azithromycin, tussicaps and dexamethasone to treat a severe cold, cough, sore throat, etc. My question is should i stop taking the ra meds until my antibiotics and steroids are done? Or should i just continue as normal, don't want to get sicker than i already am!!!! thanks

More questions for: Macrobid, Methotrexate

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Personalized review of arava (1 response)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate and the nose bleeds have now almost completely stopped. My doctor put me on Arava 3 days ago and I am on eHealth to study the effects of it.

More reviews for: Macrobid, Methotrexate

Complete drug side effects:

On eHealthMe, Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) is often used to treat urinary tract infection. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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