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Review: Metformin and Aspirin

This review analyzes the effectiveness and drug interactions between Metformin and Aspirin. It is created by eHealthMe based on 18,639 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 30, 2014: 18,639 people who reported to have interactions when taking Metformin, Aspirin are studied

Trend of Metformin, Aspirin's drug interactions, side effects and effectiveness reports (6049491)

Drug combinations in study:
- Metformin (metformin hydrochloride)
- Aspirin (aspirin)

eHealthMe real world results:

Most common interactions experienced by people in the use of Metformin, Aspirin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)5,159
Vomiting4,478
Nausea (feeling of having an urge to vomit)4,197
Diarrhoea4,062
Blood Glucose Increased3,496
Pain3,326
Renal Failure Acute (rapid kidney dysfunction)3,272
Dizziness2,865
Fatigue (feeling of tiredness)2,681
Weight Decreased2,376

Most common interactions experienced by people in long term use of Metformin, Aspirin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Renal Failure Acute (rapid kidney dysfunction)208
Vomiting158
Diarrhoea128
Hypoglycaemia (deficiency of glucose in the bloodstream)126
Renal Failure (kidney dysfunction)117
Nausea (feeling of having an urge to vomit)94
Lactic Acidosis (low ph in body tissues)84
Weight Decreased80
Anaemia (lack of blood)77
Pain74

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Metformin0.00%18.37%35.71%38.78%7.14%
Aspirin0.00%14.52%43.55%33.87%8.06%

Top conditions involved for these people * :

  1. Diabetes mellitus
  2. Hypertension
  3. Type 2 diabetes mellitus
  4. Blood cholesterol increased
  5. Diabetes mellitus non-insulin-dependent

Top co-used drugs for these people * :

  1. Glucophage
  2. Lisinopril
  3. Simvastatin
  4. Lipitor
  5. Byetta

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Aspirin, Metformin

You can also:

Complete drug side effects:

On eHealthMe, Metformin (metformin hydrochloride) is often used to treat diabetes. Aspirin (aspirin) is often used to treat blood clots. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

  • From this study (2 months ago):

  • Vitamin D deficient. High Cholesterol inherited. But while on statin drug I had a pseudo-heart attack, and became weakened and then paralyzed in lower extremities. Later found out father had same severe reaction to statin drugs. My cholesterol is still too high in using just Fish Oil 3-6-9, but don't want to try another statin :( because of side effects. In the meantime doc switched me from Metformin alone to glipizide w Metformin. I got my first ever hypOglycemic reading in the 70's and 90's. So now know what that feels like. But BS won't regulate. Latest problem of 2 weeks with severe bronchitis treated with z-pack, then prednisolone. (2 more days on pred) and my BS readings are staying in the 200s to near 400! I've increased the dosage by one pill while taking prednisone. Fasting bs did get down to 146, but that's the lowest. Now FIGHTING TO GET AWAKE AND STAY AWAKE. I'm shaky weak, and so weak that and feel like I am falling. Sleep attacks...hours go by...I'm scared I won't wake up, but can't stay awake.

    Reply

    be ware of metformin on Mar, 3, 2014:

    I am a 64 yr old female who was on metformin for 10 plus yrs. I was recently diagnosed with congestive heart failure. One of the first things the doctor took me off was metformin. I thought it was strange, so I did research and discovered that metformin can cause death. According to the people who make metformin doctors are aware of the dangers. They even put it in black boxes. This protects them from any liability so people can not sue them. Metformin is bad news. Research your meds. And I too have bouts of vertigo. I think we are all being used as guinea pigs.

    Reply

  • From this study (2 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Aspirin, Metformin

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  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

More reviews for: Aspirin, Metformin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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