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Review: taking Methadone and Gabapentin together

Summary: drug interactions are reported among people who take Methadone and Gabapentin together.

This review analyzes the effectiveness and drug interactions between Methadone and Gabapentin. It is created by eHealthMe based on reports of 1,969 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Methadone and Gabapentin >>>

What are the drugs

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,848 Methadone hydrochloride users)

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from 39,616 Gabapentin users)

On Feb, 5, 2015: 1,969 people who take Methadone Hydrochloride, Gabapentin are studied

Methadone Hydrochloride, Gabapentin outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Gabapentin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effective30.00%
(3 of 10 people)
60.00%
(6 of 10 people)
0.00%
(0 of 3 people)
71.43%
(5 of 7 people)
41.67%
(5 of 12 people)
63.64%
(7 of 11 people)
57.14%
(4 of 7 people)
0.00%
(0 of 1 people)
Gabapentin is effective22.22%
(2 of 9 people)
0.00%
(0 of 4 people)
0.00%
(0 of 6 people)
35.71%
(5 of 14 people)
21.43%
(3 of 14 people)
41.67%
(5 of 12 people)
75.00%
(3 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug Withdrawal SyndromeLoss Of ConsciousnessDepressionDepressionDrug IneffectiveDiarrhoeaBone PainPain
OverdoseNeoplasm MalignantBlood Urea IncreasedDysarthriaDiarrhoeaHypotensionAnxiety DisorderAnxiety
DehydrationMusculoskeletal StiffnessGoutDrug DependenceOedema PeripheralDehydrationSleepiness - During The DayDyspnoea
FallDrug IneffectivePain In ExtremityDental CariesFistula DischargeConfusional StateBipolar DisorderOsteonecrosis Of Jaw
DysarthriaCompleted SuicideBlood Creatinine IncreasedAbnormal BehaviourMigraineNeutropeniaAnxietyBack Pain
Electrocardiogram Qt ProlongedHypertensionDrug IneffectiveTooth AbscessNeck InjuryHaematocrit DecreasedChronic PainNausea
Tooth AbscessGrand Mal ConvulsionInfluenza Like IllnessDrug AbuseDevice Related InfectionChillsSleep Disorder Due To General Medical Condition, Insomnia TypeOedema Peripheral
Drug DependenceAnxietyFallOverdoseJaw DisorderHaemoglobin DecreasedDepression AggravatedFatigue
Drug IneffectivePetit Mal EpilepsyArrhythmia NosDrug IneffectiveDental CariesPlatelet Count DecreasedBack PainArthralgia
LethargyAstheniaIntentional OverdosePartner StressHallucinationPain In ExtremityInsomniaHypoaesthesia

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective51.28%
(20 of 39 people)
45.45%
(10 of 22 people)
Gabapentin is effective29.73%
(11 of 37 people)
26.92%
(7 of 26 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyAnxiety
DyspnoeaDyspnoea
NauseaBack Pain
Osteonecrosis Of JawAsthenia
Back PainHeadache
FatigueArthralgia
Oedema PeripheralPyrexia
HypoaesthesiaOedema Peripheral
Emotional DistressOsteonecrosis Of Jaw

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/a36.36%
(4 of 11 people)
22.73%
(10 of 44 people)
25.71%
(9 of 35 people)
13.33%
(6 of 45 people)
9.09%
(1 of 11 people)
Gabapentin is effectiven/an/an/a18.18%
(2 of 11 people)
17.50%
(7 of 40 people)
11.11%
(4 of 36 people)
2.27%
(1 of 44 people)
28.57%
(4 of 14 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aRespiratory DistressHaematocrit DecreasedDeep Vein ThrombosisAnxietyPainPainPain
Febrile NeutropeniaHypotensionWeight DecreasedPainDyspnoeaAnxietyDyspnoea
White Blood Cell Count DecreasedPyrexiaHypokalaemiaOsteonecrosis Of JawFatigueArthralgiaBack Pain
NeuroblastomaCompleted SuicideOedema PeripheralNauseaAnxietyOsteonecrosis Of JawOsteonecrosis Of Jaw
Neoplasm ProgressionCardiac ArrestParaesthesiaBack PainOedema PeripheralEmotional DistressAnxiety
TachycardiaCaecitisAstheniaDyspnoeaNauseaPyrexiaOsteomyelitis
Rhabdomyosarcoma RecurrentRespiratory ArrestPainAstheniaInsomniaDyspnoeaWeight Decreased
Oxygen Saturation DecreasedFebrile NeutropeniaConstipationBone DisorderDepressionBack PainOsteoarthritis
Pain In ExtremityHeadacheVomitingOedema PeripheralBack PainInjuryImpaired Healing
Disease ProgressionHaemoglobin DecreasedPain In ExtremityFatigueVomitingNauseaBone Disorder

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Methadone and Gabapentin on

Do you take Methadone and Gabapentin?

You are not alone! Join a related mobile support group:
- support group for people who take Methadone and Gabapentin
- support group for people who take Gabapentin
- support group for people who take Methadone Hydrochloride

Can you answer these questions (Ask a question):

  • I am a type 1 diabetic. what are some drugs i should never take with levomir and humalog?
    I am having sweats and am concerned that the drugs I am taking are the problem. Just had a CABG X3 and feel pretty well. my diabetes is type 1 and very hard to control. After 52 years I have tried many diets and different insulins. Now I just take 5 to six injections per day of the humalog and 2 of levemir.
  • Why is restoril showing poaitive in my urin when i never took this drug (2 answers)
    I have been ill for 15 years, taking Methadone all the while along with Soma and Hydrocodone for break thru pain. I now include Lyrica daily.I have had 2 back surgeries, one detailing rod and cage around L4 L5 in 2007. Most recent Nov 2013 at the Laser Spine Institute for spine decompression in that same area. Diagnosed w/ Arachnoiditis 15 yrs ago when working full time and since Methadone seems to be my only safe bet to take so that I can function. 4 years on Hizentra IVG home treatment every week. Lorazapam was prescribed for panic. Tried Diazapam more than 8-9 months ago, however that drug seems to back up in my system therefore I get no immediate relief but sort of a knock out sleep 8 hours later so we went back to Lorazapam. I am now unfortunately disabled, mostly homebound and 60 yrs old. Since this past August my urin specimen has come back positive for Restoril. This past month Restoril is still positive and described as habitual use. I am staring down a discharge from my physician who I care for, respect and admire, I never ever thought this would happen. We just took another test I offered to get another different Lab test she told me to wait so I am but its killing me. I never took a sleeping other than Unisom OTC in my Entire life. Never been prescribed Restoril, no offense but would never take it on top of what I already take and Lord knows how I would react to this drug. If I am awake all night that's just the way it is and I live with it. Why is this foreign drug showing up in my system? Please help. Thank you kindly, Louise
  • Has anyone had surgery for an av fistula ofthethorasic spine
    for the past 8 months I have had severe nerve pain and numbness after surgery for an AV fistula ib my thorasic spine
  • What are the side effects of taking methadone and cefdinir
    I know there are some antibiotics that do not go well with methadone. I need to know if anyone has ever had these two together and how well it worked or not
  • Can gabapentin be taken with theanine? (1 answer)
    Our adult son is 34 and his medical doctor is using Gabapentin for behaviors and anxiety. We (my husband and I) use Theanine for anxiety for ourselves. Our son is showing signs of anxiety and he is nonverbal. His behaviors go up when he is anxious and he also stops eating. We want to use the theanine with the gabapentin but his medical Dr. thinks its bologny. We certainly dont want to give him the theanine if there is an interaction with the gabapentin. We have talked with our pharmacist and he doesnt see that there could be a problem Our sons dr. had never even heard of "Theanine". Anyone have the answer to combining the two?

More questions for: Gabapentin, Methadone Hydrochloride

You may be interested at these reviews (Write a review):

  • Fibromyalgia, rsd, interstitial cystitis, lupus
    I have suffered chronic autoimmune conditions for over 20 years. Started out as fibromyalgia, for over a decade. Under a lot of stressors, 8 yrs ago, acquired more autoimmune conditions such as: Interstital Cystitis (IC), sjorgren's syndrome (chronic dry eye..sometimes testing + & sometimes -), RSD in right upper extremity (following cervical fusion surgery), then Lupus (sometimes + & - on bloodwork). Many MDs made me feel as if it was "in my head" b/c of all stressors in life @ the time. An Alternative Medicine/Internal Medicine MD believed in me, as well as a great endrocrinologist...HOPE was FINALLY FOUND & RESULTS GOTTEN. Acupuncture, LDN (Low Dose Naltrexone), eliminating sugar, all sugar substitutes (replacing ONLY with ORGANIC stevia), eating non-GMO foods (basically no prepacked foods that has no more than 7 "ingredients" you have no idea what they are!), eating fresh fruit/veggies, only grass fed/organic meats, fish from U.S. I SLOWLY integrated diet changes, as had great difficulty changing my diet. I was a sugarholic! Especially when stressed! Eliminating sugar, however, proved to be most immediate pain reliever. Next...LOW DOSE NALTREXONE!! (lowdosenaltrexone.org most helpful explaining & finding MDs to prescribe it..Another HUGE hurdle until the 2 MDs listed above suggested, rx'd & maintaining me on after 1 yr!) CANNOT SAY ENOUGH ABOUT LDN.. HAVE TO HAVE PATIENCE..longer have had condition(s), longer to see results! It has allowed me to have a participating life..has it cured all conditions..no..has improved quality of life..TREMENDOUSLY!! My MDs both believe RSD (in presence of other autoimmune condition(s) is basically an autonomic nervous system autoimmune disease (your nervous system NEVER stops firing! Thereby creating: severe pain, swelling, redness, skin changes, burning sensation, etc., we experience). Acupuncture helped SIGNIFICANTLY regulate the autonomic nervous system, reducing severe RSD pain..did it require alot of acupuncture? Yes..to keep "resetting" nervous system response..UNTIL LDN therapy & now require 4x's/yr for acupuncture. ALWAYS make sure an acupuncturist is an MD &/or REGISTERED as a CERTIFIED acupuncturist (google it). The diet changes were the "cherry on top of the sundae" (see, the sugarholic is still there & have to work at it everyday! BUT results in biggest pain reduction of ALL autoimmune condition symptoms..then, no dairy (except organic aged cheese, ie. Kefir, blue cheese, feta, etc), increase fresh fruits/veggies..eliminate GMO foods (google it!), etc. My husband & I both lost jobs (mine from my health..his from downsizing in company! We were on VERY limited budget. IT CAN BE DONE: buy frozen organic (or non organic if cannot afford..still changing to good eating!) fruits & veggies if too expensive for fresh..or, organic vegetable/fruit powders with organic almond or coconut milk w/chia seeds, flavored w/frozen fruit & stevia..organic pea, hemp, whey protein pwders full of amino acids are affordable on vitacost.com & look @'it as a trip to grocery store or a run to fast food (even fast food meal costs more than the powders. Etc made in smoothies!) GOOD reading & I hope I have helped change just 1 person's pain & made their lives more liveable, functional & enjoyable! I was in bed for 2 yrs! I thought i'd NEVER enjoy anything in life again..it's still a struggle @ times...but..without excruciating pain in EVERY part of my body! If u can do ONLY 1 change..do the LDN! It's $10 a month from Skip's Pharmacy in Boca Raton, FL! They ship all over there world! It's cheap & WORKS!! They are great people as well! God Bless
  • Vasculitis caused by gabapentin
    i also take but didnt have such symptom till recent; however, such could be due to gabapentin 1800 mg/d.
    also was suing at the time topamac 100 mg amitriptyline 50 mg, metoprolol 25 mg HCTZ 25 mg,Proventil inh etc.,OTC Tylenol aspirin and vitamins. Been on gabapentin about 15 months but on other meds more than 5 yrs. on and off.

    Since more than 10 weeks I developed 1 to 2 inches across reddish areas on feet and ankles not raised , and slightly dotted;total about 4 or 5 on each foot and ankle.,that dont itch or ache, dont seem to grow or subside w any cream like HC. showed to doctor,said to observe.Basic screening tests were neg,but perhaps needs more testing. We discussed possiblility of bites from various things but I doubt that.
  • Roaring in the ears from tramadol (taken with dexamethasone)
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    Back pain much better but have the roaring in right ear and can't sleep much. Also doing the Dr recommended exercises daily. Will follow up with chiropractic if this doesn't get me there.

    This is a chronic condition, maybe 20 years, no specific injury, just an accumulation of doing dumb things in my youth.
  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Neurotin as an anabolic
    Takave been taking anabolic steroids for about 6 weeks my games were linear unlock the entire time. When I started taking Neurontin with anabolic steroids my anabolism was increased by at least 30%. There was no change in diet or any other variables as far as I can tell. The only variable was the neurontin.it just so happens did my workout partner is taking Neurontin and getting the some effect. I know for a fact it affects the digestive system.

More reviews for: Gabapentin, Methadone Hydrochloride

Comments from related studies:

  • From this study (3 months ago):

  • Rosacea appeared after a few months on Methadone.

    Reply

  • From this study (4 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Gabapentin (gabapentin) is often used to treat neuralgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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