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Review: taking Methadone and Ibuprofen together

Summary: drug interactions are reported among people who take Methadone and Ibuprofen together.

This review analyzes the effectiveness and drug interactions between Methadone and Ibuprofen. It is created by eHealthMe based on reports of 666 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Methadone and Ibuprofen >>>

What are the drugs

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,842 Methadone hydrochloride users)

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from 61,621 Ibuprofen users)

On Dec, 30, 2014: 666 people who take Methadone Hydrochloride, Ibuprofen are studied

Methadone Hydrochloride, Ibuprofen outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
42.86%
(3 of 7 people)
33.33%
(1 of 3 people)
20.00%
(1 of 5 people)
75.00%
(3 of 4 people)
n/a
Ibuprofen is effective0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
0.00%
(0 of 2 people)
28.57%
(2 of 7 people)
0.00%
(0 of 6 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Duodenal Ulcer PerforationPain In ExtremityPainType 2 Diabetes MellitusOsteopeniaHypothermiaSweating - ExcessivePain
OverdosePainSweating - ExcessiveGallbladder DisorderNauseaInfectionInsomniaAnxiety
ConstipationGangreneDrug Withdrawal SyndromePainFemur FractureInsomniaJoint SprainNausea
Bulbar PalsyPneumoniaCholecystitis AcuteCardiovascular DisorderHallucination, VisualTicOsteonecrosis Of Jaw
AstheniaMultiple Drug Overdose AccidentalSepsisRib FractureHallucination, AuditoryRed FaceDyspnoea
DroolingHypotensionObesityBone DeformityAnxietyHigh Blood Cholesterol And TriglyceridesBack Pain
DysphagiaMeningococcal InfectionMalaiseFallCardiac ArrestDepression SuicidalInjury
Muscular WeaknessPeripheral Arterial Occlusive DiseaseCholelithiasisDizzinessDepressionAnorgasmiaVomiting
AreflexiaArterial Thrombosis LimbChronic Obstructive Pulmonary DiseaseLeukocytosisIntentional OverdoseWeight Gain - UnintentionalDepression
Heart Rate DecreasedPeripheral ColdnessFoot FractureIntervertebral Disc ProtrusionIntentional Self-injuryDry MouthDizziness

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective33.33%
(4 of 12 people)
55.56%
(5 of 9 people)
Ibuprofen is effective9.09%
(1 of 11 people)
11.11%
(1 of 9 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
NauseaAnxiety
AnxietyOsteonecrosis Of Jaw
InjuryBack Pain
DyspnoeaDyspnoea
Osteonecrosis Of JawAnaemia
PyrexiaAsthenia
VomitingDepression
Back PainOsteoarthritis
DizzinessNausea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/a40.00%
(2 of 5 people)
22.22%
(2 of 9 people)
12.50%
(1 of 8 people)
20.00%
(4 of 20 people)
0.00%
(0 of 1 people)
Ibuprofen is effectiven/an/an/a0.00%
(0 of 4 people)
0.00%
(0 of 9 people)
0.00%
(0 of 8 people)
10.00%
(2 of 20 people)
0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
MelaenaDysphagiaHodgkin's DiseasePainNauseaInjuryNauseaPain
Pulmonary HypertensionDroolingBrain OedemaAnxietyAnxietyPainOsteonecrosis Of JawAnxiety
VomitingMuscular WeaknessUnresponsive To StimuliOverdoseHeadacheDepressionPainOsteonecrosis Of Jaw
Condition AggravatedTracheitisDrug ToxicityPneumoniaConstipationAnxietyEmotional DistressDyspnoea
Cardio-respiratory ArrestVocal Cord DisorderPyrexiaBack PainPainNauseaPain In JawDysphagia
Alanine Aminotransferase IncreasedBulbar PalsyVentricular TachycardiaDrug ToxicityDepressionBack PainHypoaesthesiaVision Blurred
Aspartate Aminotransferase IncreasedConstipationMultiple Drug Overdose AccidentalInjuryBack PainAnaemiaAnxietyBack Pain
Abdominal PainOverdoseAnaphylactic ReactionTooth InfectionFatigueVomitingDizzinessOsteomyelitis
ApnoeaIntestinal InfarctionNauseaPyrexiaDyspnoeaChest PainChronic Obstructive Pulmonary Disease
AreflexiaIleusRespiratory DepressionGastrooesophageal Reflux DiseaseUrinary Tract InfectionOsteoarthritisAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone and Ibuprofen?

You are not alone! Join a related mobile support group:
- support group for people who take Methadone and Ibuprofen
- support group for people who take Ibuprofen
- support group for people who take Methadone Hydrochloride

Can you answer these questions (Ask a question):

  • 8 year old boy has erratic heartbeat. started tamiflu last week. do i need to quit tamiflu? he had a 104.1 temp when we started treatments.
    Shortly after being dosed with Tamiflu this morning, he had a very erratic heartbeat. He is positive for influenza last Thursday and has been on Tamiflu since and Ibuprofen to manage fever (was up to 104.1 last week). Local clinic wants to see him. I don't feel like taking him there will solve anything. Its returned to normal within an hour of dosing with Tamiflu.
  • Can i take ketorolac if i am already taking methadone everyday?
    I take methadone everyday and I have a tooth ache so can I take ketorolac with methadone?
  • I tested positive for methadone, i have never taken this drug (1 answer)
    I tested positive for methadone, I have never taken this drug. My Dr said I had to have taken it because it was there and that a false positive is out of the question. Could my meds cause methadone to show up on a urine drug test
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Is ibuprofen safe to use if i have retinitis pigmentosa?
    I have bulging disc pain that I use Ibuprofen for. I can be pain free for weeks/months and take nothing. When I have a flair up I can take up to 8x200mg per day. I have heard this may affect my RP. Can you advise?

More questions for: Ibuprofen, Methadone Hydrochloride

You may be interested at these reviews (Write a review):

  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • Wheezing stopped after topamax sessesion
    Wheezing noted by primary physician in this non-smoker. Stopped Topamax per doctor's instruction. 48 hours later was examined by physician and noted that wheezing stopped.

More reviews for: Ibuprofen, Methadone Hydrochloride

Comments from related studies:

  • From this study (5 months ago):

  • The extremely red arms and face looks like a sunburn.

    Reply

  • From this study (5 months ago):

  • The extremely red arms and face looks like a sunburn

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  • From this study (7 months ago):

  • want to make sure that there isn't ANY interactions with my med's

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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