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Review: taking Methadone and Zoloft together

Summary: drug interactions are reported among people who take Methadone and Zoloft together.

This review analyzes the effectiveness and drug interactions between Methadone and Zoloft. It is created by eHealthMe based on reports of 899 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Methadone and Zoloft >>>

What are the drugs

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,848 Methadone hydrochloride users)

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from 78,365 Zoloft users)

On Mar, 1, 2015: 899 people who take Methadone Hydrochloride, Zoloft are studied

Methadone Hydrochloride, Zoloft outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Zoloft (sertraline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effective44.44%
(4 of 9 people)
33.33%
(2 of 6 people)
25.00%
(1 of 4 people)
100.00%
(2 of 2 people)
61.54%
(8 of 13 people)
75.00%
(6 of 8 people)
0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
Zoloft is effective0.00%
(0 of 6 people)
20.00%
(2 of 10 people)
0.00%
(0 of 2 people)
25.00%
(2 of 8 people)
33.33%
(4 of 12 people)
50.00%
(2 of 4 people)
40.00%
(2 of 5 people)
n/a

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective50.00%
(16 of 32 people)
50.00%
(7 of 14 people)
Zoloft is effective29.03%
(9 of 31 people)
18.75%
(3 of 16 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/a0.00%
(0 of 1 people)
33.33%
(3 of 9 people)
24.32%
(9 of 37 people)
15.62%
(5 of 32 people)
11.11%
(5 of 45 people)
20.00%
(1 of 5 people)
Zoloft is effectiven/an/a0.00%
(0 of 1 people)
11.11%
(1 of 9 people)
5.26%
(2 of 38 people)
9.38%
(3 of 32 people)
11.11%
(5 of 45 people)
20.00%
(1 of 5 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HeadacheNauseaDepressionDepressionNauseaDrug ToxicityDrug IneffectivePain
Drug ToxicityDecreased AppetiteDental CariesDrug DependenceDeliriumDrug Screen PositiveFatigueAnxiety
VomitingDepressionDrug DependenceDysarthriaPancreatitisTremorDepressionDepression
NauseaHeadacheDysarthriaTooth AbscessMulti-organ FailureHeadacheSomnolencePyrexia
DepressionAnxietyDizzinessDental CariesIschaemiaChronic PainArthropathyBack Pain
Drug Screen PositiveInsomniaPyrexiaAbnormal BehaviourPancreatitis AcuteHepatic SteatosisKnee ArthroplastyOsteonecrosis Of Jaw
SomnolenceSleep WalkingAbnormal BehaviourDrug AbuseMetabolic AcidosisVomitingSuicidal IdeationDyspnoea
Hepatic SteatosisParkinson's Disease NosTooth AbscessTooth LossPericarditisSomnolenceOverdoseBone Disorder
IncoherentDrug IneffectiveOsteochondrosisPartner StressPulmonary OedemaIncoherentSuicidal BehaviourImpaired Healing
DyspnoeaDrug Abuser NosOsteoarthritisOverdosePyrexiaSuicidal IdeationPitting OedemaAnaemia

Most common drug interactions by gender * :

FemaleMale
AnxietyPain
PainDepression
NauseaAnxiety
ConstipationPyrexia
Oedema PeripheralDehydration
ArthralgiaConfusional State
HypoaesthesiaOsteonecrosis Of Jaw
Pain In ExtremityCellulitis
InjuryHaematuria
DepressionAsthenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aAbdominal DistensionSalivary HypersecretionPulmonary OedemaAnxietyPainPainPain
Adenovirus InfectionDrug Toxicity NosBrain OedemaDepressionDepressionAnxietyAnxiety
Acute Graft Versus Host Disease In IntestineDrug AbuseCompleted SuicideHeadacheDizzinessArthralgiaBack Pain
Viral InfectionNeoplasm MalignantDrug ToxicityCompleted SuicideOedema PeripheralInjuryDehydration
Respiratory DistressPyrexiaSubstance AbuseNauseaConstipationEmotional DistressDysphagia
Respiratory FailureVentricular TachycardiaCardio-respiratory ArrestDizzinessChest PainAnaemiaDyspnoea
ViraemiaSepsisOverdoseImpaired HealingRashPyrexiaOsteonecrosis Of Jaw
Pneumonia FungalVomitingSomnolenceWound DehiscenceWeight DecreasedOsteonecrosis Of JawOsteomyelitis
Enterococcus Test PositiveLeukaemiaVomitingUrinary RetentionPyrexiaScarHypotension
MalnutritionAbdominal PainAccidental DeathChest PainTremorBone DisorderAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone and Zoloft?

You are not alone! Join a related mobile support group:
- support group for people who take Methadone and Zoloft
- support group for people who take Methadone Hydrochloride
- support group for people who take Zoloft

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • What are the side effects of taking methadone and cefdinir
    I know there are some antibiotics that do not go well with methadone. I need to know if anyone has ever had these two together and how well it worked or not
  • Ok to take losartan and zoloft together before bed? (2 answers)
    I've been on Losartan for a year without any problem. Six weeks ago I started on 25mg of Zoloft for general anxiety. All of a sudden during cardio exercise I feel lightheadedness and a feeling like I could pass out! I stop for a moment and then I feel ok. Is this normal? I thought I'd be getting more used to it after 6 weeks, but this is something new so I figured that it is now in my body and fatigue is normal. Or perhaps taking bp meds and Zoloft might be the cause.
  • Does the thymus affect dysthymia
    joy of living is imparted to the child by the bonding process. the thymus helps in developing antibodies and setting up the immune system and its function lessens through puberty until it effectively atrophies at maturity. my thesis is that a lack of bonding interferes with the action of the thymus leading to dysthymia (Greek for bad state of mind), elsewhere described as 'chronic discontent
  • What should i expect taking zoloft and hydroxyzine? (1 answer)
    I take 25mg Zoloft for one more day and bump up to 50 mg. I also take 25mg Hydroxyzine Pamoate 3 times per day as needed. I've been on these for a week and feel worse than when I wasn't. My depressive state seems to be getting worse and the anxiety is through the roof. My home is where I felt OK but now I hate it. My skin is crawling and I feel like I want to tear it off and crawl out. Is this a normal side effect of these drugs? I am also diabetic and take several meds for that, don't know if that makes a difference.
  • Can i take ketorolac if i am already taking methadone everyday?
    I take methadone everyday and I have a tooth ache so can I take ketorolac with methadone?

More questions for: Methadone Hydrochloride, Zoloft

You may be interested at these reviews (Write a review):

  • Fluoxetine with hypnagogic hallucinations
    Was taking fluoxetine until recently for a depressive episode (suffered from depression pretty much my whole life). Strange hypnagogic hallucinations and bizarre thoughts, sometimes coupled with feeling faint. Also strong feelings of numbness for the first two weeks or so, headaches and dry mouth. Strangely only on 20mg...This is my second time on fluoxetine and the experience has been totally different (last time it seemed to make me act callously and superficially towards people, and to be generally irresponsible, going out, avoiding work etc.).

    Doctor had now changed me over to sertraline, been on it for 3 days and ok so far apart from minor headaches.
  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • The zoloft/vyvanse concoction ruined my life.
    I started taking these drugs about two months ago. I am diagnosed ADHD by a psychiatrist. I received these medications from a doctor whom I know and is married to a friend my wife. She, the doctor, gave them to me from her personal medications in a plastic baggy. I was given loose instructions for taking these on a piece of paper. I was never given the paperwork with warning signs. 10 days after starting these medications, I attacked my wife and am now separated. I am barred from seeing her and my daughter by means of a Victims Protective Order. I am a normally nonviolent person. Most who know me call me a peacemaker...a pacifist. I am still horrified by the events of that night. 15 seconds changed my life forever. I hope and pray my story helps others. Don't be naïve, as I was, when given medications. Ask questions.
  • Loss of menstruation
    Hi
    I stopped using setralin 50 µg in August 2014. (I have been taken it in 1 year for my PMS). After stopping taking the pills my period become very short in september and then desappeard. I got a funcional cyste (about 30 mm) and after 10-days treatment with progesterone I got my period in the end of oktober. Two weeks afterwards I got a spare bleeding and my gyn thought that it my be an ovulation bleeding. Anyhow I have not got my period yet. The samples taken in oktober showed low FSH and heigt E2. The doctor explained that it is posible that stopping setralin could cause this hormonal imbalance. I must say that my periods were not so regular for very long time like during that year with setralin but I had other side effects like problem with concentartion, nussea etc.
    For many years ago I was on Zoloft but I had not experienced the same problem. When I started the treatment this time they did not want to give me zoloft (because of the price). I had no choice but i experienced many symptoms from different generica of Setralin. I will meet my doctor om Monday again.

More reviews for: Methadone Hydrochloride, Zoloft

Comments from related studies:

  • From this study (3 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

    trust1983 on Dec, 3, 2012:

    Is it true in the states that a psych doc can up and just leave and refuse to treat you because you tried to kill yourself, especially if you didn't have a contact for life with you r doc?

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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