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Review: Methadose and Remeron

This review analyzes the effectiveness and drug interactions between Methadose and Remeron. It is created by eHealthMe based on 598 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 7, 2014: 598 people who reported to have interactions when taking Methadose, Remeron are studied

Trend of Methadose, Remeron's drug interactions, side effects and effectiveness reports (5339912)

Drug combinations in study:
- Methadose (methadone hydrochloride)
- Remeron (mirtazapine)

eHealthMe real world results:

Most common interactions experienced by people in the use of Methadose, Remeron:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)314
Asthenia (weakness)293
Fatigue (feeling of tiredness)225
Toxicity To Various Agents (poisoning due to various agents)202
Nausea (feeling of having an urge to vomit)186
Back Pain176
Anaemia (lack of blood)169

Most common interactions experienced by people in long term use of Methadose, Remeron:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Nausea (feeling of having an urge to vomit)6
Torsade De Pointes (a abnormal heart rate with abnormal beating pattern)6
Cardiac Arrest6
Ventricular Fibrillation (abnormally irregular heart rhythm)6
Urinary Incontinence (inability to control the flow of urine and involuntary urination)6
Activities Of Daily Living Impaired6
Faecal Incontinence (a lack of control over passing stool)6
Encephalopathy (functioning of the brain is affected by some agent or condition)4
Polytraumatism (multiple trauma)4

How effective are the drugs:

not at allsomewhatmoderatehighvery high

Top conditions involved for these people * :

  1. Pain
  2. Depression
  3. Multiple myeloma
  4. Hiv infection
  5. Hepatitis c

Top co-used drugs for these people * :

  1. Methadone hcl
  2. Seroquel
  3. Neurontin
  4. Diazepam
  5. Ativan

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methadose, Remeron

You can also:

Complete drug side effects:

On eHealthMe, Methadose (methadone hydrochloride) is often used to treat pain. Remeron (mirtazapine) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • I'm filling out this form on behalf of my brother who is dependent on methadone and also taking mirtazapine for his depression, i only found out about him taking mirtazapine a few days ago as this is when his hearing voices come to light when he called me to explain as he was scared, since then he has not been to visit his doctor but i intend to take him in tommorow but my question is that if a person was taking both medications for a period of at least 10 months and then stopped taking methodone 60ml daily without reduction could this cause an affect on the persons brain thus making them hear voices in there head? I understand that withdrawal symptoms are there from methadone, but is it possible that the person could hallucinate?


Can you answer these questions (what is this?):

More questions for: Methadose, Remeron

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More reviews for: Methadose, Remeron

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Methadose side effects
- Remeron side effects



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