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Review: Methocarbamol and Effexor Xr

This review analyzes the effectiveness and drug interactions between Methocarbamol and Effexor Xr. It is created by eHealthMe based on reports of 301 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Methocarbamol and Effexor Xr >>>

What are the drugs

Methocarbamol (latest outcomes from 3,266 users) has active ingredients of methocarbamol. It is often used in muscle spasms.

Effexor xr (latest outcomes from 21,815 users) has active ingredients of venlafaxine hydrochloride. It is often used in depression.

On Sep, 15, 2014: 301 people who take Methocarbamol, Effexor Xr are studied

Methocarbamol, Effexor Xr outcomes

Drug combinations in study:
- Methocarbamol (methocarbamol)
- Effexor Xr (venlafaxine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methocarbamol is effective0.00%
(0 of 4 people)
(2 of 2 people)
(0 of 1 people)
(0 of 1 people)
(0 of 2 people)
(0 of 1 people)
(2 of 3 people)
Effexor Xr is effective0.00%
(0 of 2 people)
(1 of 2 people)
(0 of 1 people)
(0 of 4 people)
(1 of 2 people)
(2 of 5 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
MigraineNauseaMyalgiaNervous System DisorderEmotional DistressAnxietyMemory ImpairmentDepression
Mood SwingsDiabetes MellitusNauseaNervousnessInjuryDyspnoeaDrug IneffectivePain
MyalgiaMuscle SpasmsNervousnessNeurotoxicityPulmonary EmbolismPulmonary EmbolismBlood Cholesterol IncreasedNausea
MalaiseImpulse-control DisorderMuscle SpasmsPersonality ChangeDyspnoeaChest PainFibromyalgiaBack Pain
Impulse-control DisorderHostilityMood SwingsNauseaAnxietyEmotional DistressDrug Withdrawal SyndromeAnxiety
Euphoric MoodIrritabilityIrritabilityMyalgiaChest PainInjuryAnxietyArthralgia
Feeling AbnormalMalaiseMalaiseMigraineDrug Withdrawal SyndromeType 2 Diabetes MellitusGout - ChronicInsomnia
Feeling JitteryFeeling JitteryMigraineMood SwingsDizzinessBack PainMuscle SpasmsVomiting
NauseaMood SwingsPersonality ChangeMuscle SpasmsGastritisHypoaesthesiaDepressed MoodPain In Extremity
Personality ChangeMigrainePhotophobiaMusculoskeletal StiffnessMultiple Drug OverdoseHypoglycaemiaSuicidal Ideation

Drug effectiveness by gender :

Methocarbamol is effective30.00%
(3 of 10 people)
(1 of 4 people)
Effexor Xr is effective23.08%
(3 of 13 people)
(1 of 4 people)

Most common drug interactions by gender * :

PainBack Pain
AnxietyDepressed Level Of Consciousness
Chest PainAnxiety
Back PainHypersensitivity
Suicide AttemptArthralgia
Pain In ExtremityNausea
Suicidal IdeationDrug Dependence
Drug IneffectiveDrug Abuser

Drug effectiveness by age :

Methocarbamol is effectiven/an/an/a0.00%
(0 of 4 people)
(1 of 6 people)
(2 of 6 people)
(0 of 1 people)
(1 of 1 people)
Effexor Xr is effectiven/an/an/a20.00%
(1 of 5 people)
(1 of 11 people)
(1 of 16 people)
(0 of 1 people)
(1 of 1 people)

Most common drug interactions by age * :

Pancreatitisn/aNauseaType 2 Diabetes MellitusVomitingDepressionDepressionPsychotic Disorder
GastritisPersonality ChangeSuicidal IdeationPharyngitisDepressed Level Of ConsciousnessInsomniaArthralgia
Diabetes MellitusMyalgiaSuicide AttemptMeningitis AsepticAnxietyPainWeight Decreased
Musculoskeletal StiffnessRhabdomyolysisOral HerpesBack PainNeck PainPain In Extremity
MigraineShared Psychotic DisorderAnxietyPainDysphagiaNausea
Mood SwingsPolysubstance DependenceNauseaDiabetes MellitusNauseaHeadache
PhotophobiaMajor DepressionPainDrug Withdrawal SyndromeCondition AggravatedDepression
ScreamingPancreatitisHyperlipidaemiaDrug AbuserDyspnoeaPain
VertigoPneumoniaSpinal OsteoarthritisWheezingInjuryBack Pain
Weight IncreasedRespiratory FailureOverdoseDrug DependenceAbdominal PainAnaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methocarbamol and Effexor Xr?

Get connected! Join a related mobile support group:
- support group for people who take Methocarbamol and Effexor Xr
- support group for people who take Effexor Xr
- support group for people who take Methocarbamol

Comments from related studies:

  • From this study (3 days ago):

  • My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)


    really? on Sep, 22, 2014:

    I honestly thought this was a board where we could all learn from
    Each other's experiences. Unfortunately, everyone seems to be fixated on this one poster, asking a question for a "friend" & who is supposedly mixing all types of drugs. Let's get off of the 3rd party bashing because anyone on all of those drugs needs a lot more than people on a web page. Geez!!!!


  • From this study (1 year ago):

  • I brush my hair once a day. After this brushing, the hair brush is COVERED in hair, and I must clean the brush at that time. The crown of my head shows moderate to sever hair loss, and I don't know what to do about this problem.


  • From this study (2 years ago):

  • it was right around the time in which i was on the invanz in which i gained around 30lbs.. i was on other medication before that but none of them touched the infection i had. i has to have a pic-line inserted.. and go in daily for the invanz treatments..was a 10 day order.. ever since then i cant seem to lose the weight i gained.. i have always been around 150 and now i am close to 190.. just not right and dont help with my depression.. please if you have any answers for me please i could use some.. thanks


Can you answer these questions (what is this?):

  • Has anyone been prescribed methotrexate for granuloma annulare?
    I have had GA for 2 years now, however it has gotten progressively worse the past 6 months. It has now spread over 80% of my body. I am seeing an Endocrinologist next week as I believe my thyroid may play a big role in this. My Regular Dr. suggested I speak to Endocrinologist about a drug called Met ...

  • How common is erectile dysfunction with effexor and adderall and how can it be combatted?
    I take both Adderall and effexor to treat ADHD and anxiety/depression. I have taken both for years but Adderall longer. My ability to hold an erection and to experience an orgasm has decreased.

  • Why are my medications making me look bloated
    In 2008 I started the Suboxone Program. I Started on 16mg since then, I have been up and down on my doses. I was put on this drug as a result of my addiction to to over the counter opiates. I was also prescribed Seroquel, I stopped taking the Seroquel it wasn't helping me in anyway and I gained so m ...

More questions for: Effexor Xr, Methocarbamol

You may be interested at these reviews (what is this?):

  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

  • My ex-boyfriend's effexor effects
    In my fifth year of living with my ex-boyfriend, he began taking Effexor and soon developed urinary incontinence, kidney failure and nightmares or night terrors so severe that he frequently screamed for prolonged periods, flailed and threw punches in his sleep. Upon ceasing to take Effexor, his sle ...

  • Losartan cause deep vein thrombosis
    have had two knee surgeries ,a lumbar decompression, after this three surgeries start taken Losartan potassium and two months later have had a lumbar fusion after this I suffered a Deep Vein Thrombosis, continues taken Losartan for more of year and half, I notice is a bad combination when my ...

More reviews for: Effexor Xr, Methocarbamol

Complete drug side effects:

On eHealthMe, Methocarbamol (methocarbamol) is often used to treat muscle spasms. Effexor Xr (venlafaxine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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