eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

  Tools   Community
All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms       Ask question       Write review       Answered/ Unanswered       Reviews       WellConnected

Review: Methotrexate and Milk Thistle





Summary: drug interactions are reported among people who take Methotrexate and Milk Thistle together.

This review analyzes the effectiveness and drug interactions between Methotrexate and Milk Thistle. It is created by eHealthMe based on reports of 41 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methotrexate and Milk Thistle >>>

What are the drugs

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. (view latest outcomes from 560 users)

On Dec, 13, 2014: 41 people who take Methotrexate, Milk Thistle are studied

Methotrexate, Milk Thistle outcomes

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Milk Thistle (milk thistle)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methotrexate is effectiven/a0.00%
(0 of 2 people)
n/an/an/an/a0.00%
(0 of 1 people)
n/a
Milk Thistle is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pulmonary MassLiver Function Test Abnormaln/an/an/an/an/aEscherichia Sepsis
Pulmonary OedemaHepatotoxicityUterine Polyp
Pneumonia CryptococcalPulmonary TuberculosisBlood Alkaline Phosphatase Increased
Blood Creatinine IncreasedDry Eyes AggravatedPyrexia
Disseminated Intravascular CoagulationEndometrial Hyperplasia
Lung InfiltrationAspartate Aminotransferase Increased
Meningitis CryptococcalPulmonary Tuberculosis
Upper Gastrointestinal HaemorrhageAlanine Aminotransferase Increased
HypotensionBlood Potassium Decreased
Pneumonia BacterialBlood Bilirubin Increased

Drug effectiveness by gender :

FemaleMale
Methotrexate is effective0.00%
(0 of 3 people)
n/a
Milk Thistle is effectiven/an/a

Most common drug interactions by gender * :

FemaleMale
Uterine PolypC-reactive Protein Increased
Escherichia SepsisPulmonary Oedema
Blood Alkaline Phosphatase IncreasedPulmonary Mass
Pulmonary TuberculosisRed Blood Cell Sedimentation Rate Increased
Blood Potassium DecreasedPyrexia
Endometrial HyperplasiaLymphadenitis
Alanine Aminotransferase IncreasedRespiratory Acidosis
Blood Bilirubin IncreasedGlomerulonephritis Membranous
Aspartate Aminotransferase IncreasedUpper Gastrointestinal Haemorrhage
NauseaPneumonia Bacterial

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methotrexate is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
n/a
Milk Thistle is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/an/an/aDisorientationPulmonary OedemaUterine Polyp
Euphoric MoodPulmonary MassBlood Alkaline Phosphatase Increased
PyrexiaEscherichia Sepsis
Red Blood Cell Sedimentation Rate IncreasedPulmonary Tuberculosis
Liver Function Test AbnormalAspartate Aminotransferase Increased
LymphadenitisBlood Potassium Decreased
C-reactive Protein IncreasedEndometrial Hyperplasia
Pneumonia BacterialBlood Bilirubin Increased
Respiratory AcidosisAlanine Aminotransferase Increased
HypotensionLymphocyte Percentage Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Milk Thistle?

You are not alone! Join a related mobile support group:
- support group for people who take Methotrexate and Milk Thistle
- support group for people who take Methotrexate
- support group for people who take Milk Thistle

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks
  • Can i take marijuana while taking gilenya
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate
  • Do i need to temporarily stop taking my enbrel and methotrexate (that i take every week) while i am on azithromycin for severe cold symptoms? (1 answer)
    i have RA and take Enbrel and methotrexate every week. i am currently taking azithromycin, tussicaps and dexamethasone to treat a severe cold, cough, sore throat, etc. My question is should i stop taking the ra meds until my antibiotics and steroids are done? Or should i just continue as normal, don't want to get sicker than i already am!!!! thanks

More questions for: Methotrexate, Milk Thistle

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • I need advise, badly ckd!! (1 response)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Cfs/fibro, migraine
    A strange thing happened when I started taking the Chantix for my smoking cessation...
    MY MIGRAINES AND TENSION HEADACHES WENT AWAY!!!
    As horrible as they were, and as bad as I have prayed for them to go away, I did not even notice that I didn't have the excruciating headaches anymore!!
    I stopped taking the chantix and the headaches gradually came back but it took me awhile to make this correlation. Once I did, I started taking the chantix again. it started working immediately... taking the migraines and neck pain away again! Now, I can take 1/2 of a pill every other day and that seems to keep the migraines away! There are side effects and I don't know if it would work for everyone but it sure worked for me!
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.

More reviews for: Methotrexate, Milk Thistle

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Milk Thistle (milk thistle) is often used to treat fatty liver. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

About - Terms of service - Privacy policy - Press - Testimonials - Contact us

 
© 2014 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.