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Home > Methotrexate > Naproxen > Methotrexate and Naproxen

Review: Methotrexate and Naproxen

Summary: drug interactions are reported among people who take Methotrexate and Naproxen together.

This review analyzes the effectiveness and drug interactions between Methotrexate and Naproxen. It is created by eHealthMe based on reports of 2,960 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methotrexate and Naproxen >>>

What are the drugs

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

Naproxen (latest outcomes from 21,923 users) has active ingredients of naproxen. It is often used in pain.

Trend of naproxen reports

On Nov, 13, 2014: 2,960 people who take Methotrexate, Naproxen are studied

Methotrexate, Naproxen outcomes

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Naproxen (naproxen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methotrexate is effectiven/a25.00%
(2 of 8 people)
0.00%
(0 of 3 people)
20.00%
(1 of 5 people)
66.67%
(2 of 3 people)
50.00%
(2 of 4 people)
25.00%
(1 of 4 people)
n/a
Naproxen is effectiven/a42.86%
(3 of 7 people)
0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
25.00%
(1 of 4 people)
0.00%
(0 of 4 people)
57.14%
(4 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cytolytic HepatitisAnaemiaBlood Albumin DecreasedAbdominal PainDevice FailurePulmonary FibrosisDisseminated TuberculosisArthralgia
Transaminases IncreasedProstate CancerGastrointestinal HaemorrhageNauseaClavicle FractureDiverticulitisNeutropeniaPyrexia
PyrexiaPyrexiaRenal ImpairmentMalaiseImpaired HealingKlebsiella InfectionMeningitis TuberculousDrug Ineffective
ArthralgiaGastroenteritisCerebrovascular AccidentDizzinessFemur FractureFatigueLymph Node TuberculosisNausea
JaundiceTuberculosis Of Central Nervous SystemArthritisLiver Function Test AbnormalPneumoniaGeneral Physical Health DeteriorationImmune Reconstitution SyndromeRheumatoid Arthritis
Prothrombin Level DecreasedLymph Node TuberculosisRespiratory ArrestOedema PeripheralVomitingPolyneuropathyGenital UlcerationHeadache
CholestasisArthritisAnaemiaPneumonitisRespiratory FailureAnxietyTuberculosis Of Central Nervous SystemPain
Blood Bilirubin IncreasedMeningitis TuberculousNosocomial InfectionArthritisDeathEnterococcal InfectionRenal FailureDyspnoea
Autoimmune HepatitisDisseminated TuberculosisTachycardiaLiver InjuryToxic Epidermal NecrolysisInterstitial Lung DiseaseSeptic ShockVomiting
Herpes ZosterImmune Reconstitution SyndromeOccult Blood PositiveAbdominal MassAutoimmune HepatitisCandidiasisWoundInjection Site Pain

Drug effectiveness by gender :

FemaleMale
Methotrexate is effective28.57%
(6 of 21 people)
33.33%
(2 of 6 people)
Naproxen is effective31.82%
(7 of 22 people)
16.67%
(1 of 6 people)

Most common drug interactions by gender * :

FemaleMale
ArthralgiaPyrexia
PyrexiaDrug Ineffective
NauseaDyspnoea
Drug IneffectiveArthralgia
PainRheumatoid Arthritis
HeadacheNausea
VomitingCough
Rheumatoid ArthritisOedema Peripheral
FatigueChest Pain
Injection Site PainPulmonary Fibrosis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methotrexate is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
7.14%
(1 of 14 people)
18.18%
(2 of 11 people)
57.14%
(4 of 7 people)
12.50%
(1 of 8 people)
Naproxen is effective0.00%
(0 of 1 people)
n/a0.00%
(0 of 3 people)
33.33%
(1 of 3 people)
7.14%
(1 of 14 people)
33.33%
(3 of 9 people)
28.57%
(2 of 7 people)
12.50%
(1 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPyrexiaPyrexiaPainOedema PeripheralRheumatoid ArthritisArthralgiaDrug Ineffective
VomitingArthralgiaFlushingDiarrhoeaArthralgiaPyrexiaNausea
Hodgkin's DiseaseArthritisPyrexiaNauseaNauseaDrug IneffectiveArthralgia
Condition AggravatedInjection Site PainArthralgiaInjection Site PainDrug IneffectiveDyspnoeaPneumonia
HypoglycaemiaMulti-organ FailureHeadacheRheumatoid ArthritisPyrexiaNauseaPyrexia
HeadacheDisseminated Intravascular CoagulationNauseaCoughHeadachePainFatigue
HepatitisJuvenile ArthritisRespiratory FailurePyrexiaChest PainHeadacheCough
Juvenile ArthritisDiplopiaTachycardiaHypotensionOedema PeripheralInjection Site HaemorrhageAsthenia
Histiocytosis HaematophagicDrug Rash With Eosinophilia And Systemic SymptomsDrug IneffectiveGastrointestinal HaemorrhagePruritusVomitingPulmonary Fibrosis
ArthralgiaHistiocytosis HaematophagicAtrophyDyspnoeaPainMyalgiaRheumatoid Arthritis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Naproxen?

You are not alone! Join a related mobile support group:
- support group for people who take Methotrexate and Naproxen
- support group for people who take Methotrexate
- support group for people who take Naproxen

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

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    (Asked by a 60 year old woman who has Diarrhea Associated With Medications, Sciatica, Si Joint Disease, and takes Naprosyn)
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    (Asked by a 57 year old woman who has Migraine Without Aura, Anxiety And Stress, Major Depression With Psychotic Features, Bilateral Multilobar Pneumonia, Ankylosing Spondylitis, and takes Zyprexa, Methotrexate)
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    (Asked by a 56 year old woman who has Hign Blood Pressure, Osteoporosis Postmenopausal, Rheumatoid Arthritis, and takes Methotrexate)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms s ...

More questions for: Methotrexate, Naproxen

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More reviews for: Methotrexate, Naproxen

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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