eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

  Tools   Community
All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms       Compare drugs       Ask question       Write review       Answered/ Unanswered       Reviews

Review: taking Methotrexate and Oxycontin together

Summary: drug interactions are reported among people who take Methotrexate and Oxycontin together.

This review analyzes the effectiveness and drug interactions between Methotrexate and Oxycontin. It is created by eHealthMe based on reports of 1,265 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Methotrexate and Oxycontin >>>

What are the drugs

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,233 Methotrexate users)

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from 42,288 Oxycontin users)

On Jan, 27, 2015: 1,265 people who take Methotrexate, Oxycontin are studied

Methotrexate, Oxycontin outcomes

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Oxycontin (oxycodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methotrexate is effective100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
n/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/a
Oxycontin is effective100.00%
(1 of 1 people)
100.00%
(2 of 2 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
40.00%
(2 of 5 people)
n/a0.00%
(0 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveSepsisSquamous Cell CarcinomaPsoriasisTremorBacteraemiaIntervertebral DiscitisPain
AnaemiaRenal Failure AcutePyrexiaIncision Site PainDrug DependenceThrombocytopeniaIntervertebral Disc DisorderNausea
VomitingEndocarditis BacterialFeeling AbnormalProcedural PainDrug Withdrawal SyndromePyrexiaParaparesisOedema Peripheral
RashCellulitisFatigueBreast TendernessSuicidal IdeationPneumonia BacterialStaphylococcal SepsisArthralgia
PancytopeniaRheumatoid ArthritisFallUterine SpasmPainDysphagiaAnaemiaPyrexia
Malignant Neoplasm ProgressionAnaemiaDyspepsiaEctopic PregnancyMental DisorderVenous Thrombosis LimbHyponatraemiaAnaemia
NeutropeniaLung NeoplasmDyspnoea ExertionalPainNauseaSkin UlcerSeptic ShockAnxiety
ThrombocytopeniaSquamous Cell CarcinomaEar PainPostpartum DepressionFlatulenceRed Blood Cell Count AbnormalEmpyemaDyspnoea
White Blood Cell Count DecreasedPainFlushingIntermittent ClaudicationArthralgiaFallArthritis BacterialBack Pain
Bone Marrow FailureDecreased AppetiteMental DisorderOedema PeripheralDry MouthPneumonia PneumococcalBack PainFatigue

Drug effectiveness by gender :

FemaleMale
Methotrexate is effective40.00%
(2 of 5 people)
0.00%
(0 of 2 people)
Oxycontin is effective62.50%
(5 of 8 people)
100.00%
(2 of 2 people)

Most common drug interactions by gender * :

FemaleMale
PainOedema Peripheral
NauseaPain
ArthralgiaWeight Decreased
Oedema PeripheralCellulitis
VomitingChest Pain
AnaemiaArthralgia
AnxietyDepression
FatigueConstipation
PyrexiaAsthenia
FallBack Pain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methotrexate is effectiven/an/an/an/a0.00%
(0 of 1 people)
14.29%
(1 of 7 people)
n/a50.00%
(1 of 2 people)
Oxycontin is effectiven/an/an/an/a100.00%
(1 of 1 people)
30.00%
(3 of 10 people)
3.70%
(1 of 27 people)
100.00%
(2 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPancreatitisMulti-organ FailureDyspnoeaNauseaPainFatiguePain
StomatitisTransfusion ReactionWhite Blood Cell Count DecreasedDrug IneffectivePyrexiaPainOedema Peripheral
Anorectal DisorderMyeloid LeukaemiaHyponatraemiaVomitingOedema PeripheralNauseaArthralgia
Clostridium Test PositiveSeptic ShockCardiac Failure CongestiveDiarrhoeaRheumatoid ArthritisOedema PeripheralFall
HypophagiaAcute Monocytic LeukaemiaPlatelet Count DecreasedPainChest PainArthralgiaNausea
Mucosal InflammationDecreased AppetiteLeukopeniaHeadacheWeight DecreasedOsteoarthritisDyspnoea
Vaginal DisorderHeadacheMulti-organ FailureLoss Of ConsciousnessTremorAnaemiaAnxiety
VomitingVomitingCatheter Related InfectionPyrexiaBack PainPyrexiaFatigue
Abdominal PainCrohn's DiseasePneumonia StreptococcalMalaiseAnaemiaSinusitisBack Pain
Blood Culture PositivePyrexiaPyrexiaInjection Site PainDepressionHeadacheAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Oxycontin?

You are not alone! Join a related mobile support group:
- support group for people who take Methotrexate and Oxycontin
- support group for people who take Methotrexate
- support group for people who take Oxycontin

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Would the tinnitus abate with if i discontinue methotrexate?
    I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
  • Can i take humira while i still have pinpoint red spots on my skin? i have been told to stop the methotrextrate and they started me on prednisone to clear it up, i am scheduled to start humira.
    I have been diagnosed with R/A and started taking Methotrextate and Folic Acid. I began to break out like I had the measles. Was told it was a reaction to the methotrextate. I was taken off of it and given a large dose of prednisone. My question is I am scheduled to start taking Humira injections and I have been off of the methotrextate 24 days and it has not cleared up yet. Is is safe to start the Humira injections?
  • What does unmasking mean; and does it mean that i always had hight cholesterol and triglycerides, or did actemra increase them?
    I have failed many RA meds, and now receive actemera x's 10 months I have never had high cholesterol or triglycerides and did not get my cholesterol checked except for the baseline 2/2014 and 12/2014 I was 198 TChol and now am 245; my tri up 85 points. my MD said that now that my inflammation is normal it shows my true cholestorol. I don't understand.
  • I amwondering if i have myathesia gravis (1 answer)
    I am thinking that after a long bout of going nowhere with Drs. That I might have Myathesia Gravis. My Grandmother had it and I am thinking that my brother had it when he was born.He failed to thrive at first as he was unable to suck very well. He did make it though with a forced feeding of milk and bananas. He was sickly all his life though and recently died of cancer. I noticed that my eye is drooping on the left side. I have periods of extream fatigue, my left arm is tingly and I can't seem to feed myself without changing to my right hand. I have spinal stenosis and severe pain in my hip area but my right big toe seems to be tingly from time to time. I also have a swallow problem that causes me to choke or throw up the food or drink. Pills stay part way down a lot. My G.I. guy wants to strech my esophegus. I tend to eat soft foods and stay away from steak or anything chewy. I have congestive heart failure, sudden cardiac death, syncope all of which I greatfully managed to survive. I have fibromyalgia, and some nodules on my chest wall ( i forget what that is called) I have had 5 or 6 bouts with Costochrondritus which was way worse than actually having my heart stop. Costo hurts like a beech! I am frequently short of breath, exercize intolerant and have trouble holding my water.I have good dsys and bad days. Also my left hand and the base of my scalp goes all numb and tingly sometimes. There is also a terrible electric shock type feeling in my mid back area that makes me completely stop in my tracks and feel like I have been hit with a 350 lb pro football player. I have been hypokalimic after taking water pills (Ferosimide) i have taken prendisone for the Chosto and feel better immediatly, but I have mental reactions to too much Prendisone. I am very allergic to NSAID'S and pennicillian. Anyone got any ideas that the Drs have maybe not thought of... I would sure like to get better and go dance but the last time I danced I lasted 3 minutes before I had to fall into a chair.

More questions for: Methotrexate, Oxycontin

You may be interested at these reviews (Write a review):

  • Mensis cycle and oxycontin
    I have severe back injuries. When I lived in another state, I was put on oxycontin and immediately my menstrual cycle (period] stopped for 1 year. When I moved to another state, I stopped taking this drug and my period returned normal. I eventually had to go back on this drug, (oxycontin) and since this time, 2 years now, I again have not had a period since beginning. If you are on this drug and are worried about your period stopping, fear not, it is a normal side effect. Hope this helps. ..
  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Which issue has caused my periodontitis, my fibromyalgia or spinal stenosis? (2 responses)
    At the age of 38 yrs old, I was diagnosed with Fibromyalgia and Spinal Stenosis. Obviously I had both of the disease for some years, and was struggling with the pain and symptoms for some time before I finally got checked, went through years being told they didn't find anything, told I had Herniated disks in My back only. Now with all the findings, there are 7 Herniated disks from My neck to My lower back.
    Also since 2010, I was diagnosed with Periodontitis and have been losing all of My teeth in the top of My mouth.
    I am 44 yrs old now, have been on disability for the last 4 years. I am down to 6 teeth in the top of My mouth, since having 1 removed just last week. They are telling Me that 3 more need to come out, and I am trying not to sink into total depression, especially since these are now My front teeth. I have a appointment today for a Denture Exam.

    I started researching today to see if this Periodontitis is related to either My Spinal Stenosis or My Fibromyalgia. Especially since I once again looked up the definition for Periodontitis. Which States;

    **Periodontal Disease and Bone Health. Periodontitis is a chronic infection that affects the gums and the bones that support the teeth. Bacteria and the body's own immune system break down the bone and connective tissue that hold teeth in place.

    Of course with My disease of Spinal Stenosis and the bone loss as well as the nerve narrowing, I thought the breaking down of the bone in the gums might have a connection. Research didnt find any linking.

    Now with Fibromyalgia, research showed 6 out of 17 thousand that they found. LOL Wow.. Well I guess I am "Number 7". Lucky Me! But it does make more sense now that looking at the definition. It is a Chronic infection (which Fibromyalia does create these) that effects the gums and bones. Bacteria and The Body's own Immune System break down the bone and connective tissue that hold the teeth. Which with Fibromyalgia, our Immune System is always all kinds of "Crazy"!

    Oh course you can not have any of these diseases, or any other health issues and wind up with Periodontitis. It happens. But I know from lots of reading, researching and living with Fibromyalgia, that it is "Very Possible"!

    I would sure like to know what others with these 2 diseases are experiencing.
    Have a Blessed Day.
  • Who cares about the patient? (1 response)
    I can't believe I'm still alive but quality of life is greatly diminished and no one cares. Not one doctor cares about how this one dr. prescribed all these drugs over a period of 5 years and I lost everything. I flat-lined sept 18, 2005 and was told by dr there in er that I would live 1-5 years and I had just lost my job as letter-carrier of over 17 years and my daughter was killed in dec of 2000, which I will always feel great responsibility because I knew I should have called her, it would have saved her life as she was killed in the firdale village apt fire and she didn't live there, she lived with me she was only 20 years old. So this crappy dr steven a creelman of seattle just kept throwing pills at me, telling me there was nothing wrong with any of the pills just me. I feared dr's and still do, I know they are just people and most people are good and caring but a lot are not. The Celebrex started after I was hit by a truck on the job in march of 2000. I will admit it relieved some pain but I had side affects immediately, within days to weeks. I was told by the crappy dr to shut up and take them as he originally told me they were not anti-inflamatorys but a new drug that did not upset stomach but they did. I felt trapped because it was an L&I and I didn't want to lose my job and so healthy and strong figured w/PT and rest I could overcome the accident pain which was lower back and neck well I couldn't sleep from pain and stomach but I couldn't tell crappy dr it would do no good. My daughter was killed Christmas night and that's a very hard one. I went back to work because my job was most of my life and I had friends at work. I continued to have more problems from Celebrex and I thought my stomach was on fire, it was blood clots that broke lose and I had to have an operation on my small instestine and what was worse is creelman, the crappy dr, when he told me it was an emergency umbililical hernia I told him I was going to get papers from owcp DOL as I would be off work at least 6 weeks. He said NO!!!!!!!!!! He closed the door and told me no, no I won't say it's from Celebrex when He really did know it was. I had an endoscopy 6 months later and that specialist said no more Celebrex. After that operation I just never felt good again I was swelling up my legs etc and fatique all kinds of not feeling good things and I was pissed at the crappy dr who by the said to me that no other dr would diagnose any different or believe me. So, it was in July of 04 and I was so sick I just went in there andhe was on vaction so another dr ran a bunch of blood tests for hiv which I told her was impossible and lupus and a few other things but no one there looked at any of the drugs except the pain medication which ironically was one of the only ones that didn't contribute to dvt & PE. when creelman got back I was still so sick I had left work and said I would be back in 2 weeks after I had some PT and rest. I couldn't sleep. That's when he prescribed REMERON. It was for sleep which it did help but I gained 50 lbs and within a couple months acquired tonsillitis, bhroinchitis, pneumonia, Phlebitis and a dvt which instead of referring me to a specialist he just presibed me an anti-inflammatory and another anti-depressant plus all the drugs He gave tons of samples which were never in noted in my files. I think he should have to pay me MONEY!! I have none since I have no job and I feel so terrible I wish I could just have my job back. And my Daughter but my health has been a Hematologist and injectable blood thinners. I hate the state of wash medical care about doctors but not the patients and I have no money to sue and it has been my experience not to mention crappy doctor SO WHO DO THE PATIENTS THAT ARE BADLY AFFECTED BY CRAPPY DCTORS GO TO? Oh I also couldn't be in the class-action suit because I didn't flat-line from heart attack. REALLY?
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine

More reviews for: Methotrexate, Oxycontin

Comments from related studies:

  • From this study (5 months ago):

  • All lesions necrosis
    Painful granulomas
    I live in chronic pain and fatigue

    Reply

    Lisa on Sep, 4, 2014:

    Female 55 I have bechets. Diagnosed at 39. I take every medication on that list except I dropped methotrexate. I worse since I dropped it. And I have every symptom including ganglion cyst which needs to be surgically removed to the throat lesion. I can barely function. The only 5hing I dont have is the allergic cough. I did have mrsa phenomia once. Oh most recently plursey. I have been ivig dependent for 13 years.

    Reply

  • From this study (12 months ago):

  • want to find out if these drugs would cause semen discolouration (yellow, greenish)

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Oxycontin (oxycodone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

About - Terms of service - Privacy policy - Press - Testimonials - Contact us

 
© 2015 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.