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Review: Metoprolol Tartrate and Simvastatin

Summary: drug interactions are reported among people who take Metoprolol Tartrate and Simvastatin together.

This review analyzes the effectiveness and drug interactions between Metoprolol Tartrate and Simvastatin. It is created by eHealthMe based on reports of 9,166 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Metoprolol Tartrate and Simvastatin >>>

What are the drugs

Metoprolol tartrate has active ingredients of metoprolol tartrate. It is often used in high blood pressure. (view latest outcomes from 40,412 users)

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 80,812 users)

On Dec, 14, 2014: 9,166 people who take Metoprolol Tartrate, Simvastatin are studied

Metoprolol Tartrate, Simvastatin outcomes

Drug combinations in study:
- Metoprolol Tartrate (metoprolol tartrate)
- Simvastatin (simvastatin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Metoprolol Tartrate is effective10.00%
(1 of 10 people)
(9 of 29 people)
(9 of 22 people)
(19 of 45 people)
(30 of 65 people)
(18 of 34 people)
(11 of 19 people)
(2 of 4 people)
Simvastatin is effective9.09%
(1 of 11 people)
(5 of 25 people)
(10 of 26 people)
(14 of 29 people)
(32 of 66 people)
(20 of 35 people)
(10 of 18 people)
(1 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
MyalgiaRhabdomyolysisAnxietyRhabdomyolysisRhabdomyolysisMyocardial InfarctionComaPain
RhabdomyolysisMyalgiaPainMyocardial InfarctionDizzinessRhabdomyolysisMulti-organ DisorderDyspnoea
HypotensionArthralgiaAstheniaAnxietyMyalgiaSyncopeDiabetic KetoacidosisMyocardial Infarction
AstheniaCardiac Failure CongestiveFatigueDizzinessMyocardial InfarctionCardiac ArrestPneumoniaNausea
Renal Failure AcuteDizzinessErythemaChest PainDyspnoeaDyspnoeaAcute Myocardial InfarctionFatigue
Cardiac ArrestRenal Failure AcuteRenal Failure AcuteRenal Failure AcutePalpitationsAbdominal Pain UpperEscherichia SepsisChest Pain
Blood Creatine Phosphokinase IncreasedDifficulty In WalkingAbdominal PainFatigueRenal Failure AcuteCardiac Failure CongestiveHepatic CirrhosisAnxiety
Renal FailureMyositisSkin HyperpigmentationFallCoughNauseaAutoimmune HepatitisDizziness
DyspnoeaFatigueHypoaesthesiaDyspnoeaAnxietyCardiac DisorderCholangitis SclerosingCardiac Failure Congestive
FatigueDyspnoeaDry SkinBenign Prostatic HyperplasiaNauseaConfusional StateMyocardial InfarctionAsthenia

Drug effectiveness by gender :

Metoprolol Tartrate is effective48.05%
(37 of 77 people)
(62 of 151 people)
Simvastatin is effective50.00%
(36 of 72 people)
(57 of 142 people)

Most common drug interactions by gender * :

PainMyocardial Infarction
Myocardial InfarctionAnxiety
Chest PainDizziness
AnaemiaChest Pain
Cardiac Failure CongestiveFatigue
AstheniaCardiac Failure Congestive

Drug effectiveness by age :

Metoprolol Tartrate is effectiven/an/an/a100.00%
(1 of 1 people)
(10 of 26 people)
(6 of 24 people)
(24 of 75 people)
(58 of 216 people)
Simvastatin is effectiven/an/an/an/a28.00%
(7 of 25 people)
(5 of 18 people)
(29 of 70 people)
(52 of 212 people)

Most common drug interactions by age * :

Atrial FibrillationSudden DeathNauseaNephrogenic Systemic FibrosisMyocardial InfarctionNauseaMyocardial InfarctionPain
Viral InfectionAccidental ExposureNeuropathy PeripheralHypotensionBlood Cholesterol IncreasedPainPainDyspnoea
Respiratory ArrestMuscular WeaknessAstheniaHypertensionMyocardial InfarctionDyspnoeaFatigue
Non-small Cell Lung Cancer MetastaticHypovolaemiaGastrointestinal DisorderChest PainAnxietyChest PainNausea
Fluid Intake ReducedHyponatraemiaDehydrationOedema PeripheralChest PainNauseaMyocardial Infarction
Disease ProgressionHypotensionAbdominal PainPainFatigueCardiac Failure CongestiveDizziness
Pain In ExtremityCoronary Artery DiseaseBronchitisDyspnoeaAnxietyCardiac Failure Congestive
Pancreatitis AcuteComplications Of Transplanted HeartDyspepsiaInjuryHypotensionAsthenia
Tobacco AbuseSepsisArthralgiaDepressionBack PainAtrial Fibrillation
VomitingPyelonephritisEmotional DistressVomitingAstheniaAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Metoprolol Tartrate and Simvastatin?

You are not alone! Join a related mobile support group:
- support group for people who take Metoprolol Tartrate and Simvastatin
- support group for people who take Metoprolol Tartrate
- support group for people who take Simvastatin

Can you answer these questions (Ask a question):

  • I had bladder cancer and my doctor put me on metformin should i get off this
    I do not want to take this metformin if it may cause my bladder cancer to come badk
  • I have been told by my gastroenterologist that i have gastroparesis, what are my treatment options, if any?
    I've had a CT scan and a Gastric Emptying study completed. My stomach is only 35% emptied after 4 hours, it should be at least 90% empty at that point. I have a colonoscopy and esophagealendoscopy scheduled for the first week of the year. What are my treatment options at this point?
  • Will taking simvistatin for dyslipidemia for 5 yrs cause my liver to ache/hurt?
    Been taking simvastatin for about 5 yrs, but in the last 2-3 months have been experiencing ache and sometimes pain from my lower right front emanating around my right side and into my lower back, I have been tested for a possible urinary tract infection that came in negative, doctors are unsure of what could be going on at this point, I am suspicious of the simvastatin affecting my liver but am not sure because of the long time I have been using it and not experiencing any problem until now
  • Is type 2 diabetes reversible after stopping plavix after a year being on the drug?
    Can any Plavix, Protonix or Metoprolol can type 2 diabetes and can it be reversible after stopping the meds? I experience severe leg cramps in my muscles. I was on Atorvastatin for high cholesterol for 8 months before being taken off. If anyone can answer any of my questions it will be greatly appreciated.
  • When was this study made? can i sue merck?
    I had a cerebral hemmorage and stroke. Was lucky and was at a major casino in Las Vegas. I had surgery through my groin to stop the bleed. I was then left in a coma for 2 months. When I started to wake up I could not move, eat, swallow, I did not know who I was or who my husband of 40 years were. I had to be taught everything over again. I had intense therapy. Physical, speech, cognitive, etc. It was over a year before I caught swallow soft food under supervision. Over a year before I was able to learn how to transfer from my bed to a wheelchair. I lost over 2 years of my life. I am now still recovery but I do have a quality of life that they told me I would never have. I was 2 weeks before my 60 birthday and the only drug I every took was Simvastian. Which was a very common drug I thought was harmless. My story was even published in my local newspaper.


More questions for: Metoprolol Tartrate, Simvastatin

You may be interested at these reviews (Write a review):

  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • Metoprolol tartate* bad side effects
    This drug caused me to gain 25 pounds, it caused depression, exhaustion, vivid dreams, joint pain, personality changes, I walk/jog frequently and could no longer jog at all. At one point I had vision problems, things would "jump" so badly that I couldn't drive (I am not sure what that was, they said whatever it was it was not my eyes. Confusion, memory problems. I think my infrequent SVTs were made worse. It made my life a living hell. My children finally said that if I didn't do something they would! I found a new Dr. and I was taken off of it and a review of all my original cardiac tests came back totally normal and I didn't need it anyway. And the only way I would ever take this medicine is if it were a last resort. There are other drugs that would have worked that have a lot less side effects. A cardiac nurse told me that Metoprolol is one of the worst for side effects. My husband has serious heart issues and was put on this med..I have noticed a lot of the same changes in him and I will work to have them change his medication also.
  • Androgel for secondary hypogonadism
    Severe swelling in legs, ankles and feet after being on my feet for more than one hour. Pain in calves and ankles. Feels like they're being squeezed or compressed. Pain dissipates after laying down for a few hours. Swelling never completely dissipates. Always some swelling in ankles.
  • Bad hair days due to medication i think, is prednisolone the culprit and if so wiil things get back to normal?
    My hair has changed from a slightly wavy thick head of, to frizzy, still a good lot of hair. I did have a 1 month spell of more than usual hair loss. I have been on Prednisolone since July 2013 30grm a day to start with reducing, at present 9 mg per day. The texture and look is not sitting well with me.
  • Simvastatin side effects (2 responses)
    I have taken this drug to reduce my high cholesterol. It has done a good job keeping it down,
    but may be the cause of the symptoms I listed above.

More reviews for: Metoprolol Tartrate, Simvastatin

Comments from related studies:

  • From this study (6 months ago):

  • I also have a hot feeling in my skin mostly in knees and shins. When taking Norpace, Tikosyn had
    same effect. Discontinued them.


  • From this study (7 months ago):

  • Since being put on Xarelto 20 mg on April 25th 2014 i have developed severe to moderate roving joint pain.


  • From this study (7 months ago):

  • Tickle in throat about even with jawline. I feel like I could put my finger on it. Only tickles in 1 spot. Causes a coughing spasm so bad that people think I am choking. Sometimes tickle happens when I swallow causing the same coughing spasm. Sometimes I wheeze after one of the choking fits, and that lasts about 1/2 of an hour. Usually sucking on a piece of hard candy ends the coughing for awhile. I have been doing this for about 7 months. Swallow test performed and it is normal,


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Complete drug side effects:

On eHealthMe, Metoprolol Tartrate (metoprolol tartrate) is often used to treat high blood pressure. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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