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Review: Milk Thistle and Metformin





Summary: drug interactions are reported among people who take Milk Thistle and Metformin together.

This review analyzes the effectiveness and drug interactions between Milk Thistle and Metformin. It is created by eHealthMe based on reports of 59 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Milk Thistle and Metformin >>>

What are the drugs

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. (view latest outcomes from 560 users)

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (view latest outcomes from 100,893 users)

On Nov, 28, 2014: 59 people who take Milk Thistle, Metformin are studied

Milk Thistle, Metformin outcomes

Drug combinations in study:
- Milk Thistle (milk thistle)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Milk Thistle is effectiven/an/an/an/a0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/an/a
Metformin is effectiven/an/an/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ThrombocytopeniaHypoacusisHypoacusisn/aSepsisMetastases To Central Nervous Systemn/aNausea
Muscular WeaknessTinnitusDeafnessLoss Of HairMuscular WeaknessTonsillitis
Metastases To Central Nervous SystemEar DiscomfortEar DiscomfortDiarrheaThrombocytopeniaAsthenia
DiplopiaDeafness NeurosensoryDeafness NeurosensoryDiplopiaAnaemia
Cerebral HaemorrhageDepressed Level Of ConsciousnessTinnitusCerebral HaemorrhageAbdominal Tenderness
DeafnessDiarrheaFebrile Neutropenia
Cerebrovascular AccidentLoss Of HairPruritus
Tinnitus AggravatedFatigue
Thrombocytopenia
Dysphonia

Drug effectiveness by gender :

FemaleMale
Milk Thistle is effective0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
Metformin is effective100.00%
(1 of 1 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
NauseaFebrile Neutropenia
FlushingTonsillitis
DiarrhoeaAbdominal Tenderness
FatigueOdynophagia
AstheniaThrombocytopenia
PruritusDysphonia
SyncopeCerebral Haemorrhage
HypotensionDecreased Appetite
EpistaxisHaemoglobin Decreased
InsomniaAnaemia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Milk Thistle is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
Metformin is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/an/aThyroid CancerInsomniaFatigueTonsillitis
NauseaPruritusAbdominal Tenderness
AstheniaNauseaFebrile Neutropenia
EpistaxisDehydrationDysphonia
FatigueSomnolenceAnaemia
PruritusDiarrhoeaOdynophagia
FlushingHypotensionThrombocytopenia
UrticariaLiver DisorderAsthenia
Sense Of OppressionTachycardiaHaemoglobin Decreased
Feeling HotAbdominal DistensionCerebral Haemorrhage

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Milk Thistle and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Milk Thistle and Metformin
- support group for people who take Metformin
- support group for people who take Milk Thistle

Can you answer these questions (Ask a question):

  • I had bladder cancer and my doctor put me on metformin should i get off this
    I do not want to take this metformin if it may cause my bladder cancer to come badk
  • I have been told by my gastroenterologist that i have gastroparesis, what are my treatment options, if any?
    I've had a CT scan and a Gastric Emptying study completed. My stomach is only 35% emptied after 4 hours, it should be at least 90% empty at that point. I have a colonoscopy and esophagealendoscopy scheduled for the first week of the year. What are my treatment options at this point?
  • What drugs cause male breast enlargement (2 answers)
    At age 62 breast seam to enlarge over the last two years
  • How to deal with low blood pressure caused by metformin
    I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope.

    I reduced Accupril until I am completely off Accupril. Still the BP was too low and I then reduced Metformin to one tab a day. The BP came back and gradually became too high , i.e., 150/92. I have to put Accupril back on at 5/2 mg then 5/4 mg then finally at 5/8 mg. This seems to be optimal but the Blood Sugar is at just above 100, sometimes 106. I wish to increase Metformin back to 2 a day but afraid Bp will become too low.

    Any input would be appreciated.
  • Could prilosec cause an elevated blood sugar
    I've been on Prilosec for about 1 month & my blood sugars have been elevated starting shortly after I started on it. could Prilosec be causing it? Nothing else has changed with my meds or lifestyle.

More questions for: Metformin, Milk Thistle

You may be interested at these reviews (Write a review):

  • Hair loss with metformin hydrochloride usage
    I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this drug should post that this is a side effect as so many have been complaining of the same side effect. I also began having problems with my teeth and always prided myself of having great teeth with no problems. I also understand that if there is a deficiency of Vitamin B12 that this together with taking this drug can cause these issues of hair loss and mouth/teeth problems. Again; I feel this should be totally and more readily informed to anyone taking this drug. I don't feel that anyone should have to give up things important to them to maintain a healthy way of living...I am going to see my physician and discuss what other options that may exist as I am not feeling very comfortable with this drug and the side effects I am experiencing.
  • Ranexa and erectile dysfunction
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
  • Victoza and liver cancer (cholangiocarcinoma)
    My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreatic cancer are similar, is there a link between Victoza and cholangiocarcinoma?
  • I need advise, badly ckd!! (1 response)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
  • Olfactory issues due to metformin use
    I've found that the metformin does not smell especially bad, but when I first started taking it, I could smell something horrible - to the point where I pulled apart my cupboards and fridge, fully expecting to find some maggot-riddled rotting meat. Eventually I realized I was smelling normal smells as hideous. I was on metformin 1/2 pill twice daily for a month, then a full pill twice daily. After about a month of that, I went off metformin for a week, being out of town without my prescription. When I resumed, that night I thought my husband had hideous breath. After we both brushed our teeth, nothing has changed. I recognized the rotting meat smell from my previous experience, and this is when I decided to cross reference metformin and olfactory issues.

More reviews for: Metformin, Milk Thistle

Comments from related studies:

  • From this study (9 months ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

Complete drug side effects:

On eHealthMe, Milk Thistle (milk thistle) is often used to treat fatty liver. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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