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Review: Mirtazapine and Tramadol





Summary: drug interactions are reported among people who take Mirtazapine and Tramadol together.

This review analyzes the effectiveness and drug interactions between Mirtazapine and Tramadol. It is created by eHealthMe based on reports of 1,182 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Mirtazapine and Tramadol >>>

What are the drugs

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from Mirtazapine 17,934 users)

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (view latest outcomes from 41,501 users)

On Nov, 28, 2014: 1,182 people who take Mirtazapine, Tramadol are studied

Mirtazapine, Tramadol outcomes

Drug combinations in study:
- Mirtazapine (mirtazapine)
- Tramadol (tramadol hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Mirtazapine is effective0.00%
(0 of 4 people)
40.00%
(4 of 10 people)
25.00%
(1 of 4 people)
66.67%
(4 of 6 people)
50.00%
(2 of 4 people)
33.33%
(1 of 3 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
Tramadol is effective0.00%
(0 of 5 people)
71.43%
(5 of 7 people)
50.00%
(2 of 4 people)
40.00%
(2 of 5 people)
28.57%
(2 of 7 people)
20.00%
(1 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Serotonin SyndromeSuicidal IdeationConvulsionLipase IncreasedDizzinessGastrooesophageal Reflux DiseaseGastrooesophageal Reflux DiseaseAnxiety
AgitationDepressionRheumatoid ArthritisBlood Amylase IncreasedSuicidal IdeationDyspepsiaDrug ToxicityPain
AstheniaDyspepsiaLoss Of ConsciousnessAbdominal PainAnxietyHaemorrhoidsHyperlipidaemiaDyspnoea
Suicidal IdeationConstipationCondition AggravatedDementiaParaesthesiaAbdominal DistensionHypertensionNausea
FatigueOedemaDysaesthesiaIrritabilityUrinary RetentionConstipationHypoglycaemiaArthralgia
TremorFaeces HardNeuropathy PeripheralNeuromaAgitationOedemaHypoalbuminaemiaHeadache
ConvulsionHaemorrhoidsObesitySleep DisorderH1n1 InfluenzaRectal HaemorrhageDiarrhoeaDepression
DizzinessRectal HaemorrhageDiabetes MellitusGas - FlatulenceIncontinenceFaeces HardDiabetic KetoacidosisFall
AnxietyAbdominal DistensionMovement DisorderMenstruation IrregularMalaiseDepressionArthralgiaAsthenia
VomitingGastrooesophageal Reflux DiseaseSleep DisorderLethargyDepressionSuicidal IdeationAcute SinusitisFatigue

Drug effectiveness by gender :

FemaleMale
Mirtazapine is effective42.86%
(9 of 21 people)
38.46%
(5 of 13 people)
Tramadol is effective30.43%
(7 of 23 people)
42.86%
(6 of 14 people)

Most common drug interactions by gender * :

FemaleMale
AnxietyAnxiety
PainPain
ArthralgiaNausea
DyspnoeaDyspnoea
HeadacheConfusional State
DepressionWeight Decreased
DizzinessVomiting
AstheniaFatigue
FatigueHeadache
Vision BlurredBack Pain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Mirtazapine is effectiven/an/a0.00%
(0 of 4 people)
0.00%
(0 of 7 people)
41.18%
(7 of 17 people)
21.43%
(3 of 14 people)
50.00%
(2 of 4 people)
14.29%
(2 of 14 people)
Tramadol is effectiven/an/a25.00%
(1 of 4 people)
12.50%
(1 of 8 people)
27.78%
(5 of 18 people)
26.67%
(4 of 15 people)
50.00%
(2 of 4 people)
0.00%
(0 of 14 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Convulsionn/aConstipationSerotonin SyndromeHeadachePainAnxietyNausea
Cardio-respiratory ArrestDepressionHyperhidrosisAnxietyDrug IneffectivePainAnxiety
ComaDyspepsiaMultiple Drug OverdoseArthralgiaFallFallConfusional State
ApnoeaHaemorrhoidsSuicidal IdeationDepressionDiabetes MellitusHypotensionPain
OsteoarthritisAbdominal DistensionDepressionAgitationDyspnoeaDiarrhoeaVomiting
ObesityGastrooesophageal Reflux DiseaseAbdominal DistensionDizzinessDepressionHeadacheDyspnoea
Patellofemoral Pain SyndromeFaeces HardHeadacheVision BlurredFatigueDehydrationBack Pain
Stress FractureRectal HaemorrhageAnxietyHyperhidrosisNauseaBack PainFall
Type 2 Diabetes MellitusOedemaConvulsionAstheniaHeadacheDizzinessArthralgia
LeiomyomaSuicidal IdeationInsomniaPyrexiaCompleted SuicideArthralgiaFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Mirtazapine and Tramadol?

You are not alone! Join a related mobile support group:
- support group for people who take Mirtazapine and Tramadol
- support group for people who take Mirtazapine
- support group for people who take Tramadol

Can you answer these questions (Ask a question):

  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (1 answer)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • Does mirtazapine cause dehydration? (1 answer)
    Dehydrated lately. Urine is very concentrated showing dehydration. Wondering if the drug in question is the cause.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (2 answers)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
  • Can you loose weight while taking hydroxyzine?
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?

More questions for: Mirtazapine, Tramadol

You may be interested at these reviews (Write a review):

  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.

    My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.

    I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).

    I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.

    I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.

    I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.

    My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.

    As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.
  • No noticeable effects
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Patients having false positives while on remeron
    I have had a few patients complain they are failing drug tests for Amphetamines while on remeron, and have claimed to have not used any type of Amphetamine or any (Mixed Salts). These patients are all or were on probation, parole, or under some stipulation. Iv realized most of these patients are taking another psych med. The list consists of insomnia meds such as Ambien(zolpidem), Sonata(zaleplon),Lunesta(eszopiclone). Also the Anti-Depressants Lexapro (escitalopram)and Prozac (fluoxetine). One of my patients was on Diazepam (Valium). I have switched medicines, particularly the Ambien, Lexapro, and Prozac have reversed the false negative. I prescribe many of my patients remeron. I'm a big believer in its effects on my patients moods and everyday depression. I have heard this happening before, but this was the first time I have ever had this happen to one of my own patients.(These were 5 separate patients in the span of 16 months) Of course none of these patients were criminalized based on lab results, but the issue still lies there. I know this is common for a lot of script meds to give false positives for narcotics. This is just obviously one I am putting out there. Let me know if anyone has experienced something similar.
  • Horrific nightmares taking naproxen
    I've Taking naproxen 500mg twice a day for 3 weeks on a course for 6 months, I've been having horrific dreams worse than horrer movies, the most recent is involving my ex & current partner where I had a psychotic stalker (my ex) switched around because in the dream I dump my partner for my ex, well the things that have been going on in my dreams are scary to the point I've woken up screaming/ crying, body is covered in sweat & it's stopping me from sleeping more, I get around 2 hours sleep a night off them..... I mean dripping, this dream was so horrific I had to post a review which I woke up around 15 mins ago, I have nightmares quiet often but never this bad

More reviews for: Mirtazapine, Tramadol

Comments from related studies:

  • From this study (2 months ago):

  • Acute onset. August LFT's normal, Mirtazapine added Sept and Oct LFT's and lipids elevated.

    Reply

  • From this study (2 years ago):

  • Is it safe to take these two drugs together?

    Reply

  • From this study (2 years ago):

  • also take vitamin d3 2000iu once a day for 5+ yrs

    Reply

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Complete drug side effects:

On eHealthMe, Mirtazapine (mirtazapine) is often used to treat depression. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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