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Review: taking Morphine Sulfate and Tramadol together

Summary: drug interactions are reported among people who take Morphine Sulfate and Tramadol together.

This review analyzes the effectiveness and drug interactions between Morphine Sulfate and Tramadol. It is created by eHealthMe based on reports of 2,349 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from 19,049 Morphine sulfate users)

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from 41,537 Tramadol users)

On Jan, 29, 2015: 2,349 people who take Morphine Sulfate, Tramadol are studied

Morphine Sulfate, Tramadol outcomes

Drug combinations in study:
- Morphine Sulfate (morphine sulfate)
- Tramadol (tramadol hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Morphine Sulfate is effective57.14%
(4 of 7 people)
50.00%
(3 of 6 people)
25.00%
(1 of 4 people)
33.33%
(1 of 3 people)
20.00%
(1 of 5 people)
66.67%
(2 of 3 people)
0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
Tramadol is effective25.00%
(1 of 4 people)
0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
20.00%
(1 of 5 people)
22.22%
(2 of 9 people)
40.00%
(2 of 5 people)
0.00%
(0 of 2 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StateDyspnoeaRhabdomyolysisSomnolenceFatigueMemory ImpairmentHypotensionPain
PneumoniaPyrexiaSepsisHomicidal IdeationNausea And VomitingMigraineExhaustion, Fatigue, Lethargy, Tiredness, WearinessNausea
VomitingVomitingRenal Failure AcuteHepatosplenomegalySphincter Of Oddi DysfunctionPain - ElbowSweating - ExcessiveAnxiety
SomnolenceDysphagiaRespiratory FailureHepatic SteatosisPancreatitis ChronicExhaustion, Fatigue, Lethargy, Tiredness, WearinessDyspnoea
Respiratory ArrestMuscular WeaknessLiver Function Test AbnormalHyperphagiaCholecystitisPain - KneeBack Pain
Abdominal PainSpeech DisorderBack PainHypersexualityNightmareBone PainAsthenia
HypotensionRespiratory ArrestDyspnoeaLeft Ventricular HypertrophyHigh Blood PressureSleep DisorderFatigue
PyrexiaAsthmaComaIntentional OverdoseHyperlipasaemiaParanoia AggravatedHeadache
Muscular WeaknessTrismusHypocalcaemiaImpulse-control DisorderDyspnoeaConstipation AggravatedAnaemia
Renal Failure AcutePneumoniaPulmonary OedemaHepatic CirrhosisMultiple Drug OverdoseMood SwingsVomiting

Drug effectiveness by gender :

FemaleMale
Morphine Sulfate is effective33.33%
(7 of 21 people)
40.00%
(4 of 10 people)
Tramadol is effective18.18%
(4 of 22 people)
20.00%
(2 of 10 people)

Most common drug interactions by gender * :

FemaleMale
PainAnxiety
NauseaPain
AnaemiaDyspnoea
DyspnoeaNausea
FatigueVomiting
AnxietyBack Pain
AstheniaDepression
Back PainConfusional State
HeadacheAbdominal Pain
ArthralgiaSomnolence

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Morphine Sulfate is effectiven/an/a100.00%
(1 of 1 people)
28.57%
(2 of 7 people)
9.52%
(2 of 21 people)
21.43%
(6 of 28 people)
25.00%
(1 of 4 people)
0.00%
(0 of 8 people)
Tramadol is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 5 people)
21.43%
(3 of 14 people)
9.52%
(2 of 21 people)
20.00%
(1 of 5 people)
0.00%
(0 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
HyperaesthesiaSepsisAnal FistulaAnxietyHeadachePainNauseaDyspnoea
CryingBone PainAnal AbscessHeadacheNauseaAnxietyArthralgiaPain
Discomfort NosArthralgiaCholecystitis ChronicDyspnoeaDepressionNauseaAstheniaFall
Anxiety NecTumour Lysis SyndromeCystChillsChest PainHypoaesthesiaBone DisorderAnaemia
DistressRespiratory FailureNauseaPainDrug Withdrawal SyndromeDiarrhoeaAnaemiaFatigue
Drug Exposure During PregnancyPneumoniaPancreatitisPneumoniaSuicidal IdeationDepressionDiarrhoeaConfusional State
Sudden DeathRenal FailureSphincter Of Oddi DysfunctionDrug AbusePainVomitingOsteoarthritisAsthenia
SomnolenceAbdominal PainAmnesiaArthralgiaBack PainPain In ExtremityWeight Decreased
Abdominal PainVomitingVision BlurredAnxietyFatigueDyspnoeaConstipation
Depressed Level Of ConsciousnessPainMusculoskeletal StiffnessAbdominal PainAbdominal PainDepressionBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Morphine Sulfate and Tramadol?

You are not alone! Join a related mobile support group:
- support group for people who take Morphine Sulfate and Tramadol
- support group for people who take Morphine Sulfate
- support group for people who take Tramadol

Can you answer these questions (Ask a question):

  • What are healthy steps should i take against cronary artery disease
    I feel sharp pains just below my left breast . At first i thought it was a breast cancer but ii ran a test that cancelled that out. Now, i strongly suspect a coronary artery disease. I also feel similar pains at my feets, restlessness at night and a bit of hallicinations at night. I also have high blood pressure.
  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Can tramadol usage cause a low white blood cell count?
    Low WBC of 2.7 on 10/21/15 and then 3.8 on 12/08/15
    Can these things be connected?
  • Does morphine cause mouth ulcerations
    one month after beginning the drug morphine I developed mouth ulcerations on my mouth palate. My mouth and face has developed soreness and painful pressure.
  • Is osteoarthrisis caused by drinking alcohol
    Chronic pain in spine, right hip, right hand, swollen joints in both hands, swollen knees.

More questions for: Morphine Sulfate, Tramadol

You may be interested at these reviews (Write a review):

  • Tramadol and severe rls and restless arms
    After back surgery I was prescribed Tramadol for pain. After about a month I developed severe RLS and also restless arms that seemed to make it hard to breath. Like a weight on my chest. I noticed that after taking the Tramadol, only at night for sleep, the restless symptoms got worse for about an hour and then settled down some. Before long there was no settling down. My pain after several months being better in my back I, not liking to take medicine period, decided to stop the Tramadol. To my surprise my RLS came to almost a complete halt. After about a week it was gone completely.
  • Mom died of stomach blockage while on tramadol
    my mom was taking tramadol for hip pain. she went in the hospital for a hip replacement and died 3 days after the surgery in the hospital from an intestinal blockage
  • Using tramadol with anti-depressants
    Using Tramadol with Anti-depressants

    I was taking Tramadol for pain instead of Endone to cut out the opiates as well as my usual anti-depressant. After about 6 months of feeling dizzy spells and nausea I stumbled across information that these two medications should not be mixed. After all of the extensive tests they did to find out why I had these symptoms, I informed my Doctor of what I had discovered. Much the their embarrassment, they realised I was correct and immediately took me off the tramadol. I just thought I would share this information in case any one else is going through what I did.
  • Prostatitis and prostate cancer acceleration due to anaesthetics
    Caught Chlamydia in 1978. Interestingly, the partnered girl's sister worked in an aviary; and I found out later that Chlamydia originates from handling birdshit and birds are the carriers. Chlamydia was undiagnosed at the time, so it was listed under 'Non-specific urethritis'. Chlamydia wasn't named until about 8 years later. I was given tetracycline and told to stay off alcohol and sex. Yeah, really?

    I was 24; highly sexed, and in night clubs and pubs most nights. I laid off the alcohol and after two weeks, I was good. The laying off sex, I understood, because of contamination of others (condoms were little used in 1978 in the singles arena); so I masturbated one night... and that caused me immense in my prostate, and pain and suffering for the rest of my life.

    The ejaculation was extremely painful, and chronic prostatitis started. I was on and off medication for two years. I got light-sensitivity, which means in sunlight, I came out in burning rashes. I became allergic to tetracycline.

    The message? Consultants are generally poor at communicating what not to do, and why not. Lay off sex he said. All he had to say was no sex, no masturbation; or you may suffer for the rest of your life. That would have done it.

    No-one has been able to help me with this chronic prostatitis. In the early years it would come and go, but as the years have gone on, it has become more frequent, and now it is constant.

    Four years ago I went in for major foot surgery, and flat-lined. I was in intensive care for 2 days, on a morphine drip for the pain.
    When I awoke, I knew immediately I was suffering with my prostate. It was aching badly and I was urinating frequently. The nurses were amazed with how many 'bottles' I filled in such a short time.
    For the next few months, I was in agony. I have tried every possible drug going, as well as prostate massage and the indignancy of a urethragram whilst female students were watching.

    In November 2011 I went to see another consultant, who suggested a biopsy. I was diagnosed with prostate cancer. After much research, I now know that my diet and lifestyle, coupled with inflammation of the prostate with prostatitis, has caused prostate cancer. Yes, there is a direct relationship between prostatitis and prostate cancer.

    I am now beating it, without drugs and without surgery. I have changed my diet to a vegan diet, no sugar, very little alcohol, and a lot of supplementation.

    In December 2013, I went in for more foot surgery. I was unaware about the morphine at this time, so didn't consider it being a problem. I talk to the anaesthetist, who wanted me to have an epidural (injection in the spine to numb my lower body). At no point did he talk to me about my prostate history.
    In recovery, I sensed a problem as soon as the anaesthetic began to wear off. It was like my prostate and testicles wanted to explode. I knew I was going to have problems. My intuition reminded me of three years ago with the morphine, so I asked the surgeon if he knew of these complications with morphine, but he didn't.

    I spoke to the head of the post-operative ward and asked her if she had any experience of post-operative patients who suffered with prostatitis after surgery, and she confirmed she had. So here was a nurse who knew of the problems, but the surgeon and anaesthetist didn't. This is typical in the health service... the lack of sharing.

    Not only did I suffer with the chronic prostatitis (and still am 11 month later) I was incontinent. It took 6 months of 4-times daily legal exercises to get back control of my bladder.
    For me, morphine has a dire effect on my prostate.

    Bear in mind that your prostate is designed to eliminate toxins, so it is flooded with morphine. I will do my best to ensure I check for morphine in any drugs or anaesthetics in future.

    My first PSA level was 18, 3 ears ago. I brought it down to 13.5, then 10.4, 10.3, 10.9, 11.3, 14.3 and after the last surgery it spiked at 17.5. As a result, I have gone back to a stricter, greener raw diet to bring it down again.

    Oh, and anther tip; you need to get your vitamin D3 blood count above 200n/mols (UK measure) to have any chance of not getting prostate cancer. Mine was 32 when I was diagnosed. Today it is over 200, from supplementation of 10000 ius a day. Minimum in the UK, recommended by scientists, is 75n/mols, and it's too low. OK if you have a great immune system, but not if you want to fight prostate cancer and prostatitis.

    Black African males in the Northern US states and in Europe have twice as much risk, due to lack of sunlight. Sunlight on skin promotes vitamin D3, which is essential for the immune system and production of calcium.

    Black African males need more sunlight to produce the same amount of vitamin D3 as a caucasian male. Also, any male who is bald and fat has a higher risk, so a Black African, obese bald male, has an extremely high risk of prostate cancer, unless they get their immune system in order.

    The main way to fight all this, is on a clean, raw vegetable diet, pure water, no alcohol, sugar, processed or refined food, no meat, no dairy, no vegetable oil, no exceptions, and some breath-taking regular exercise. Just like we did 100 years ago. Go figure! Look at chronic disease studies of 100 years ago. 85% of all disease was from infection. Today 85% is from chronic disease.

    Your prostate eliminates toxins, and today, we are overloading it. Remove the toxins (and the stress and anxiety) and things will improve. It's a hard road; but with it is you want to be healthier and live longer.

    Good luck.
    Glenn.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Morphine Sulfate, Tramadol

Comments from related studies:

  • From this study (1 year ago):

  • want to find out of all my pain is a condition as well as my promary condition of back surgery and back pain

    Reply

  • From this study (2 years ago):

  • I always had low blood pressure but have now discovered it is high and am wondering if it is related to recent med changes or just to deterioration in underlying condition. The steroids are new. Morphine is old but recently increased to 120mg every 12hrs slow release. Furosemide and Cetirizine have been introduced since I last used to keep a check on BP results 3yrs ago. Not sure if it is suddenly high now or has been for a while but not picked up until now.

    Reply

  • From this study (2 years ago):

  • would like to know how morphine helps bipolar

    Reply

    shannon on Apr, 13, 2013:

    Not sure exact mech. of action, however, could be to raise "Feel Good" endorphines and possibly keep you more at a "near but not fully" manic point, so to speak. I know a few with depression treated with morphine for that reason...it increases the available dopamine between the nerve cells called the synapsis, in turn, giving a feeling of "well being". This effct is opposite in some people...such as scizophrenics...it seems to make them more apt
    to do stranger stuff and hallucinate. Im just a paramedic that researches stuff like this and no physician by a long shot...just picked it up after researching a patient I thought was lying to me about a depression treatment plan with narcotic medication....I had to find it out for myself and the above explanation is the guts of the study....hope it helps....I research alot of "cases" I transport to the hospital with good stories...

    Reply

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Complete drug side effects:

On eHealthMe, Morphine Sulfate (morphine sulfate) is often used to treat pain. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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