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Review: Mucinex and Benadryl

This review analyzes the effectiveness and drug interactions between Mucinex and Benadryl. It is created by eHealthMe based on 434 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 4, 2014: 434 people who reported to have interactions when taking Mucinex, Benadryl are studied

Trend of Mucinex, Benadryl's drug interactions, side effects and effectiveness reports (7421391)

Drug combinations in study:
- Mucinex (guaifenesin)
- Benadryl (diphenhydramine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Mucinex, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)386
Anxiety342
Pyrexia (fever)318
Diarrhoea266
Nausea (feeling of having an urge to vomit)236
Back Pain226
Chest Pain218
Pain216
Osteoarthritis (a joint disease caused by cartilage loss in a joint)182
Cough178

Most common interactions experienced by people in long term use of Mucinex, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Ileus (a painful obstruction of the ileum or other part of the intestine)8
Febrile Neutropenia (fever with reduced white blood cells)8
Constipation8
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)3
Hypoglycaemia (deficiency of glucose in the bloodstream)3
Blood Potassium Increased (damage to or disease of the kidney)3
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)2
Diabetes Mellitus Inadequate Control2
Diabetic Nephropathy (diabetic kidney disease)2
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)2

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Mucinex0.00%50.00%50.00%0.00%0.00%
Benadryl0.00%0.00%0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Pain
  2. Hypertension
  3. Prophylaxis
  4. Cough
  5. Chronic obstructive pulmonary disease

Top co-used drugs for these people * :

  1. Heparin sodium injection
  2. Aspirin
  3. Albuterol
  4. Seroquel
  5. Lasix

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Related topic: Benadryl, Mucinex

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Complete drug side effects:

On eHealthMe, Mucinex (guaifenesin) is often used to treat cough. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 months ago):

  • Starting having severe muscle cramps and fasciculations. Cramping to all muscles- even my neck and abdomen

    Reply

  • From this study (1 year ago):

  • carmen on Nov, 16, 2012:

    I am 25yr. Old female I was prescribed a muscle relaxer 500mg, mucinex 600mg, ibuprofen 600mg,is it ok to take all meds at the same time or should I wait some time before taking the next med.

    Reply

  • From this study (4 years ago):

  • Do any of these medications contain any form of mercury? My son can't excrete mercury well. Do any contain sulfa? He is allergic to sulfa.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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