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Review: taking Mucinex and Benadryl together

Summary: drug interactions are reported among people who take Mucinex and Benadryl together.

This review analyzes the effectiveness and drug interactions between Mucinex and Benadryl. It is created by eHealthMe based on reports of 492 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Mucinex has active ingredients of guaifenesin. It is often used in cough. (latest outcomes from 5,837 Mucinex users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,395 Benadryl users)

On Feb, 11, 2015: 492 people who take Mucinex, Benadryl are studied

Mucinex, Benadryl outcomes

Drug combinations in study:
- Mucinex (guaifenesin)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Mucinex is effective26.67%
(4 of 15 people)
40.00%
(2 of 5 people)
0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
33.33%
(1 of 3 people)
n/an/an/a
Benadryl is effective25.00%
(3 of 12 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
40.00%
(2 of 5 people)
25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pleural EffusionDepressed MoodBlood Potassium IncreasedBlood Potassium IncreasedConstipationCarpal Tunnel Syndromen/aDyspnoea
Confusional StateDysarthriaBronchospasmAllergic ReactionsFebrile NeutropeniaMyoclonic JerksNausea
Decubitus UlcerHomicideDiplopiaIleusWeaknessBack Pain
EpistaxisHypotensionMuscle CrampsCarpal Tunnel SyndromeExhaustion, Fatigue, Lethargy, Tiredness, WearinessAnxiety
Cardiorenal SyndromePostpartum DepressionBronchospasmMyoclonic JerksFingernails - BluishPain
Atrial FibrillationMental DisorderType 2 Diabetes MellitusExhaustion, Fatigue, Lethargy, Tiredness, WearinessEndometriosisPyrexia
AnaemiaDiplopiaDiabetes Mellitus Inadequate ControlFingernails - BluishChest Pain
AstheniaMuscle CrampsDiabetic NephropathyWeaknessOsteoarthritis
GangreneAggressionGlucose Tolerance ImpairedEndometriosisCough
CardiomegalyDisorientationHypoglycaemiaOedema Peripheral

Drug effectiveness by gender :

FemaleMale
Mucinex is effective26.32%
(5 of 19 people)
25.00%
(2 of 8 people)
Benadryl is effective35.00%
(7 of 20 people)
37.50%
(3 of 8 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
AnxietyPyrexia
Back PainPneumonia
PainChest Pain
DyspnoeaDizziness
OsteoarthritisAnaemia
InjuryHeadache
Oedema PeripheralAsthenia
CoughNausea
DiarrhoeaPain In Extremity

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Mucinex is effectiven/a33.33%
(1 of 3 people)
0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
27.78%
(5 of 18 people)
25.00%
(1 of 4 people)
0.00%
(0 of 4 people)
0.00%
(0 of 3 people)
Benadryl is effectiven/a0.00%
(0 of 3 people)
33.33%
(1 of 3 people)
0.00%
(0 of 2 people)
26.32%
(5 of 19 people)
75.00%
(3 of 4 people)
0.00%
(0 of 4 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
InfectionDrug Screen PositiveInfectionNauseaDyspnoeaNauseaAnxietyDyspnoea
Respiratory DistressCardio-respiratory ArrestHepatomegalyUpper Respiratory Tract InfectionPneumoniaVomitingCoughBack Pain
Therapeutic Response DecreasedAdverse ReactionHepatitisInsomniaPyrexiaBack PainAtelectasisAsthenia
Transplant RejectionKawasaki's DiseaseCondition AggravatedChest PainDyspnoeaPainConstipation
HypertensionPenile SwellingUrinary Tract InfectionArthralgiaPyrexiaGastritisPleural Effusion
Hyperparathyroidism SecondaryViral RashBronchitisDizzinessAnaemiaOsteoarthritisPneumonia
ConvulsionScarlet FeverCardiac Failure CongestiveBlood Pressure IncreasedPainInjuryAnxiety
Cerebral InfarctionHepatic Enzyme IncreasedHeadacheOtorrhoeaUrinary Tract InfectionDiarrhoeaOsteoarthritis
EncephalomalaciaOropharyngeal PainInfluenza Like IllnessBack PainAnxietyToothacheChest Pain
ThrombocytopeniaGianotti-crosti SyndromeCholecystitisMyalgiaDepressionTooth FractureNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Mucinex and Benadryl on

Do you take Mucinex and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Mucinex and Benadryl
- support group for people who take Benadryl
- support group for people who take Mucinex

Can you answer these questions (Ask a question):

More questions for: Benadryl, Mucinex

You may be interested at these reviews (Write a review):

  • Sids/benedryl infant stopped breathing
    We are devastated. Our grand daughter was being breastfed and mother only took 1 tablet of Benedryl 25 mg and healthy baby girl died of SIDS following morning. Any information is appreciated.
  • Diphenhydramine and mental acuity
    For at least 10 years, I have taken diphenhydramine 50 mg. at bedtime for insomnia and allergies. The results have been that I sleep well with no hangover or any cognitive impairment. If I experience vertigo from allergies, I may take an additional 50 mg. but never exceeding 100 mg in a 24 hour period.

    After reading the report regarding an Alzheimer's study finding that after taking as little as 4mg diphenhydramine daily for more than 3 years, dementia rates were high.

    I stopped the diphenhydramine one night. I experienced symptoms of deep brain pulsating pain and severe insomnia. After 4 hours, I took 50 mg diphenhydramine and slept very well. The next night I took 37.5 mg. diphenhydramine, slept very well. However, some of my tasks require layers of mental challenges in which I became slower.

    My question is how did the study recipients obtain 4 mg doses of diphenhydramine when the standard over-the-counter (OTC) availability in tablets is 25 mg? How reliable is the information submitted from the study subjects? What manufacturer's diphendramine was used, or were there several?

    I felt sharper mentally when on 50 mg daily than so far on 37.5 mg.
  • Rash, allergic reaction to claritin d 24 hrs
    Began taking Claritin 24 hours one day ago and immediaty broke out in hives.
  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless

More reviews for: Benadryl, Mucinex

Comments from related studies:

  • From this study (1 year ago):

  • Starting having severe muscle cramps and fasciculations. Cramping to all muscles- even my neck and abdomen

    Reply

  • From this study (2 years ago):

  • carmen on Nov, 16, 2012:

    I am 25yr. Old female I was prescribed a muscle relaxer 500mg, mucinex 600mg, ibuprofen 600mg,is it ok to take all meds at the same time or should I wait some time before taking the next med.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Mucinex (guaifenesin) is often used to treat cough. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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