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Review: taking Lunesta and Namenda together

Summary: drug interactions are reported among people who take Lunesta and Namenda together. This review analyzes the effectiveness and drug interactions between Lunesta and Namenda. It is created by eHealthMe based on reports of 60 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


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What are the drugs

Lunesta has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from 16,189 Lunesta users)

Namenda has active ingredients of memantine hydrochloride. It is often used in dementia. (latest outcomes from 7,226 Namenda users)

On May, 14, 2015: 60 people who take Lunesta, Namenda are studied

Lunesta, Namenda outcomes

Drug combinations in study:
- Lunesta (eszopiclone)
- Namenda (memantine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lunesta is effectiven/a0.00%
(0 of 1 people)
(0 of 4 people)
(1 of 2 people)
Namenda is effective0.00%
(0 of 1 people)
(0 of 1 people)
(1 of 1 people)
(0 of 2 people)
(0 of 1 people)
(0 of 1 people)

Drug effectiveness by gender :

Lunesta is effective0.00%
(0 of 3 people)
(1 of 4 people)
Namenda is effective33.33%
(1 of 3 people)
(0 of 4 people)

Drug effectiveness by age :

Lunesta is effectiven/an/a0.00%
(0 of 1 people)
(0 of 2 people)
(0 of 1 people)
(1 of 3 people)
Namenda is effectiven/an/a0.00%
(0 of 1 people)
(0 of 2 people)
(0 of 1 people)
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StateHypokalaemiaInsomniaHair LossUrinary RetentionVentricular HypokinesiaGastroparesisConfusional State
Gait DisturbanceCardiac ArrestGastroparesisPancreatitis AcuteStressInsomnia
AggressionTorsade De PointesDehydrationMyocardial InfarctionConvulsion
Transaminases IncreasedElectrocardiogram Qt ProlongedSomnolenceArteriosclerosisGeneral Physical Health Deterioration
GlomerulonephritisGastrointestinal HaemorrhageCytolytic HepatitisAbnormal BehaviourDehydration
MalaisePulse AbnormalRenal FailureFeeling Abnormal
DizzinessBlood Pressure FluctuationVaginal InfectionInfection
DepressionNeuroleptic Malignant SyndromeBlood Potassium IncreasedCatatonia
Renal Failure AcuteAngiopathyInflammationHypertensive Crisis
DiarrhoeaPyrexiaHair LossEpilepsy

Most common drug interactions by gender * :

Confusional StateInsomnia
ConvulsionDrug Ineffective
General Physical Health DeteriorationDysgeusia
Feeling AbnormalGait Disturbance
InfectionConfusional State
Hypertensive CrisisNeuroleptic Malignant Syndrome
CatatoniaBlood Pressure Fluctuation
InflammationBlood Albumin Decreased
Cytolytic HepatitisBedridden

Most common drug interactions by age * :

Patellofemoral Pain Syndromen/an/an/aPain In ExtremityGastroparesisRespiratory ArrestConfusional State
Stress FracturePatellofemoral Pain SyndromeIntracardiac ThrombusDehydration
Type 2 Diabetes MellitusOsteoarthritisDiastolic DysfunctionGeneral Physical Health Deterioration
OsteoarthritisObesityAtrial FibrillationConvulsion
ObesityInsomniaLeft Ventricular HypertrophyInfection
Blood Triglycerides IncreasedLeiomyomaCardiac Failure CongestiveFeeling Abnormal
HyperprolactinaemiaReflux GastritisPneumoniaInsomnia
LeiomyomaReflux OesophagitisUpper Respiratory Tract InfectionHypertensive Crisis
Blood Cholesterol IncreasedType 2 Diabetes MellitusPulmonary HypertensionCatatonia
Weight IncreasedAphasiaDisorientation

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lunesta and Namenda?


You are not alone! Join a related support group:
- support group for people who take Lunesta
- support group for people who take Namenda

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Lunesta, Namenda

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Comments from related studies:

  • From this study (5 years ago):

  • request what kind of expectorant or sore throat when taking these drugs


Complete drug side effects:

On eHealthMe, Lunesta (eszopiclone) is often used to treat insomnia. Namenda (memantine hydrochloride) is often used to treat dementia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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