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Review: Naproxen and Lamictal Xr

This review analyzes the effectiveness and drug interactions between Naproxen and Lamictal Xr. It is created by eHealthMe based on reports of 109 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Naproxen and Lamictal Xr >>>

What are the drugs

Naproxen sodium (what 3,795 Naproxen Sodium users reported?) has active ingredients of naproxen sodium. It is used in pain.

Lamictal xr (what 410 Lamictal Xr users reported?) has active ingredients of lamotrigine. It is used in epilepsy.

On Aug, 14, 2014: 109 people who take Naproxen Sodium, Lamictal Xr are studied

Naproxen Sodium, Lamictal Xr outcomes

Drug combinations in study:
- Naproxen Sodium (naproxen sodium)
- Lamictal Xr (lamotrigine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Naproxen Sodium is effective33.33%
(1 of 3 people)
(1 of 3 people)
(1 of 1 people)
(1 of 4 people)
(0 of 1 people)
(2 of 3 people)
(0 of 1 people)
Lamictal Xr is effective0.00%
(0 of 2 people)
(1 of 2 people)
(1 of 2 people)
(1 of 3 people)
(1 of 1 people)
(1 of 2 people)
(2 of 2 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyskinesiaMovement DisorderRashEmotional Distressn/aSuicidal IdeationChronic Fatigue SyndromePain
ConvulsionJoint SwellingPruritusChest PainConfusionConfusionEmotional Distress
Eye Movement DisorderMonarthritisStevens-johnson SyndromeMusculoskeletal PainChronic Fatigue SyndromeSuicidal IdeationNausea
AphasiaArthralgiaRash PruriticGeneral Physical Health DeteriorationCognitive DisorderSuicidal ThoughtsHeadache
VomitingPhotophobiaMovement DisorderAnxietyAphasiaIrritabilityFatigue
RashArthritisMucous Membrane DisorderFearSleep ApneaFatigueBack Pain
PyrexiaPhotosensitivity ReactionPulmonary EmbolismFallDepressionPain In Extremity
White Blood Cell Count DecreasedMyalgiaEmotional DisorderSweating IncreasedAnxietyHypoaesthesia
ArthralgiaMuscle AtrophyHematuriaHematuriaAphasiaLymphadenopathy
Muscular WeaknessConvulsionUrinary IncontinenceInjury

Drug effectiveness by gender :

Naproxen Sodium is effective45.45%
(5 of 11 people)
(1 of 5 people)
Lamictal Xr is effective50.00%
(5 of 10 people)
(2 of 5 people)

Most common drug interactions by gender * :

Emotional DistressPain
PainFaecal Incontinence
NauseaBack Pain
InjuryGeneralised Erythema
ConvulsionLoss Of Consciousness
Hiatus HerniaFatigue
Intervertebral Disc ProtrusionHypoaesthesia

Drug effectiveness by age :

Naproxen Sodium is effectiven/an/an/a0.00%
(0 of 3 people)
(0 of 5 people)
(2 of 18 people)
(3 of 6 people)
(1 of 1 people)
Lamictal Xr is effectiven/an/an/a0.00%
(0 of 3 people)
(2 of 5 people)
(2 of 18 people)
(2 of 5 people)
(1 of 1 people)

Most common drug interactions by age * :

n/an/aPulmonary EmbolismDiabetes MellitusGallbladder PainPruritusPainDiplopia
FearDiabetes Mellitus Inadequate ControlAbdominal Pain UpperGeneralised OedemaBack PainRash
AnxietyAffective DisorderPulmonary EmbolismConvulsionPain In ExtremityBack Disorder
General Physical Health DeteriorationPartial SeizuresCholecystitis ChronicHerpes ZosterFatigueCognitive Disorder
Musculoskeletal PainBlood Cholesterol IncreasedBiliary DyskinesiaPapilloedemaLymphadenopathyLoss Of Consciousness
Emotional DisorderDiabetic ComplicationNauseaPainMalaiseFall
Chest PainConvulsionHeadachePleural EffusionMassNausea
Emotional DistressBlood Glucose IncreasedPruritusLocal SwellingMetastases To BoneSleep Apnoea Syndrome
VomitingInjuryVaginal SwellingHeadacheLung NeoplasmMuscle Pain
Lip SwellingPulmonary EmbolismSkin IrritationThermal BurnHepatitis CShort-term Memory Loss

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Get connected! Join a mobile support group:
- group for people who take Naproxen and Lamictal Xr
- group for people who take Lamictal Xr
- group for people who take Naproxen Sodium

Comments from related studies:

  • From this study (5 months ago):

  • I receive enough benefit from taking these medications, with varying results depending on circumstances to justify their continued use.


  • From this study (1 year ago):

  • Aphasia, stroke like, M.S. like
    MRI, negative


  • From this study (2 years ago):

  • I am 20 years old and I have been taking 60mg of Methadose liquid through a Opioid Treatment Program since late August of 2012 (gradually increased from 30-60 over the course of 3 months until November, then maintaining at 60mg since.) I have all the common symptoms such as, excessive sweating, weight gain/increased appetite, and fatigue. Symptoms of abnormal, mostly involuntary muscle/body movements have gradually increased, in frequency and severity. However, 3 months prior to starting Methadone treatment I was using heroin intravenously and had the same movement symptoms, but were far less severe. The symptoms come on about 2 hours or so after my dose, right when I can feel the methadone reach its peak. It continues all the way until the night time when I go to bed. Once I awaken in the morning I rarely experience the [annoying and embarrassing] constant movements. I take the methadone 7 days a week, and is starting to become more severe and also interacting with my daily tasks; i.e. Driving (the worst at all times), causing me to swerve and lose focus on the road, when I'm sitting, standing, on the computer as we speak, and about almost all the time throughout the day. Very little do I try to control it, because it continues all day, and if I do try to keep it under control, I have to focus very hard. I am mostly moving my upper body; moving my neck in all directions, my shoulders as well in all directions (which has caused me to pull muscles several times in the past couple months), rotating my wrists in circles, front and back, my back (upper and lower), along with my hips, as well as extending my arms outward, turning them from front to back (forearms), this is all done with strong force/penetration, (constricting) "hard" stretches. When I do try and concentrate on the movements (on my upper body), my legs and thighs feel the strongest need to constrict and move inward and out


Can you answer these questions (what is this?):

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More reviews for: Lamictal Xr, Naproxen Sodium

Complete drug side effects:

On eHealthMe, Naproxen Sodium (naproxen sodium) is often used to treat pain. Lamictal Xr (lamotrigine) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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