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Review: taking Naproxen and Methylprednisolone together

Summary: drug interactions are reported among people who take Naproxen and Methylprednisolone together.

This review analyzes the effectiveness and drug interactions between Naproxen and Methylprednisolone. It is created by eHealthMe based on reports of 80 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Naproxen and Methylprednisolone >>>

On Apr, 8, 2015: 80 people who take Naproxen Sodium, Methylprednisolone are studied

Naproxen Sodium, Methylprednisolone outcomes

Drug combinations in study:
- Naproxen Sodium (naproxen sodium)
- Methylprednisolone (methylprednisolone)

Drug effectiveness over time :


Drug effectiveness by gender :


Drug effectiveness by age :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Demyelinating PolyneuropathyNausean/an/aVomitingn/an/aArthralgia
Blood Pressure Diastolic IncreasedHiatus HerniaNauseaNausea
Heart Rate IncreasedSkin DiscolourationGastritisPain
DiarrhoeaVomitingBarrett's OesophagusBack Pain
Gastric UlcerGastric UlcerVomiting
Hepatic Enzyme IncreasedAbdominal Pain UpperInjury
Benign Oesophageal NeoplasmDrug ToxicityOsteoarthritis
AnxietyFoot AmputationDepression
GastritisGastric PerforationFatigue
Abdominal PainBronchitis

Most common drug interactions by gender * :

Back PainArthralgia
VomitingGastrooesophageal Reflux Disease
Deep Vein ThrombosisOsteoarthritis
Swelling FaceSinusitis
Gait DisturbanceAnaemia
Abdominal PainNeuropathy Peripheral
HeadacheDecreased Appetite
Pulmonary EmbolismBronchitis

Most common drug interactions by age * :

n/an/an/aAbdominal PainDeep Vein ThrombosisHypoaesthesiaArthralgiaDemyelinating Polyneuropathy
InjuryPain In ExtremityDiarrhoeaOsteoarthritisGastritis
CholelithiasisPulmonary EmbolismMitral Valve IncompetencePainVomiting
Cholecystitis ChronicGait DisturbanceHeart Rate IncreasedGastrooesophageal Reflux DiseaseBarrett's Oesophagus
Sickle Cell Anaemia With CrisisAmnesia NecDizzinessAnaemiaNausea
Back PainExacerbation Of AnxietyIntervertebral Disc ProtrusionDecreased AppetiteSalivary Hypersecretion
White Blood Cell Count IncreasedDrug DependenceTricuspid Valve IncompetenceNeuropathy PeripheralTongue Oedema
Overdose NosMuscle SpasmsInsomniaGastric UlcerSpeech Disorder
Asthmatic CrisisIntracranial Venous Sinus ThrombosisBack PainSinusitisPyrexia
Idiopathic Thrombocytopenic PurpuraCerebrovascular AccidentAnxietyInjuryDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Naproxen and Methylprednisolone?




You are not alone! Join a related support group:
- support group for people who take Methylprednisolone
- support group for people who take Naproxen Sodium

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Naproxen Sodium (naproxen sodium) is often used to treat pain. Methylprednisolone (methylprednisolone) is often used to treat inflammation. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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