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Review: Savella and Neurontin

This review analyzes the effectiveness and drug interactions between Savella and Neurontin. It is created by eHealthMe based on reports of 263 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Savella and Neurontin >>>

What are the drugs

Savella (what 3,377 Savella users reported?) has active ingredients of milnacipran hydrochloride. It is used in fibromyalgia.

Neurontin (what 57,743 Neurontin users reported?) has active ingredients of gabapentin. It is used in pain.

On Aug, 23, 2014: 263 people who take Savella, Neurontin are studied

Savella, Neurontin outcomes

Drug combinations in study:
- Savella (milnacipran hydrochloride)
- Neurontin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Savella is effective50.00%
(1 of 2 people)
0.00%
(0 of 12 people)
20.00%
(1 of 5 people)
60.00%
(3 of 5 people)
100.00%
(3 of 3 people)
n/an/an/a
Neurontin is effective100.00%
(1 of 1 people)
25.00%
(2 of 8 people)
0.00%
(0 of 2 people)
40.00%
(2 of 5 people)
27.27%
(3 of 11 people)
33.33%
(1 of 3 people)
n/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FatigueHypertensionNeuromaSuicidal IdeationFacet Joint SyndromeDepression Aggravatedn/aFatigue
AgitationNauseaSkin PlaqueNauseaMigraineNausea AggravatedPain
NauseaExhaustion, Fatigue, Lethargy, Tiredness, WearinessSeromaMusculoskeletal StiffnessFibromyalgiaIbsNausea
HeadacheFatigueStevens-johnson SyndromeTremorBack Pain - LowMiddle InsomniaHeadache
InsomniaDecreased AppetitePancreatitisPainDepressionPainAgitation
HyperhidrosisDyspnoeaCervicogenic HeadacheLoss Of ConsciousnessHigh Blood Cholesterol And TriglyceridesDrug IneffectiveInsomnia
DiarrhoeaVentricular HypertrophyExhaustion, Fatigue, Lethargy, Tiredness, WearinessSomnolenceGerdDry MouthDrug Ineffective
IrritabilityNeck PainMuscle FatigueDrug IneffectiveMyofascial Pain SyndromeFatigueVomiting
PalpitationsAbnormal DreamsUrinary RetentionCardiac DisorderHypertensionDecreased AppetiteDiarrhoea
Drug IneffectiveDiastolic DysfunctionHigh Blood PressureMalaiseUrinary RetentionIrritability

Drug effectiveness by gender :

FemaleMale
Savella is effective33.33%
(8 of 24 people)
0.00%
(0 of 3 people)
Neurontin is effective29.63%
(8 of 27 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
FatigueArthralgia
NauseaPain In Extremity
PainDry Mouth
HeadachePain
InsomniaParaesthesia
AgitationRed Blood Cell Sedimentation Rate Increased
Drug IneffectiveDrug Ineffective
VomitingMobility Decreased
DiarrhoeaAntinuclear Antibody Increased
MalaiseWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Savella is effectiven/an/an/a16.67%
(1 of 6 people)
20.00%
(2 of 10 people)
9.38%
(3 of 32 people)
0.00%
(0 of 2 people)
25.00%
(2 of 8 people)
Neurontin is effectiven/an/an/a0.00%
(0 of 6 people)
10.00%
(1 of 10 people)
12.12%
(4 of 33 people)
25.00%
(1 of 4 people)
37.50%
(3 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aHypertensionDeep Vein ThrombosisTachycardiaNauseaFatigueHeadache
FatigueNauseaCellulitisPainNauseaInsomnia
RashDiarrhoeaHyperhidrosisAgitationHeadacheBurning Sensation
FlushingVomitingExhaustion, Fatigue, Lethargy, Tiredness, WearinessDecreased AppetiteHeart Rate IncreasedFatigue
Lupus-like SyndromeRashNauseaMigraineMalaiseDiarrhoea
PainNeuropathy PeripheralFallDyspnoeaAgitation
InjuryLoss Of ConsciousnessArthralgiaPainPain
Back Pain - LowDyspnoeaHeadacheSuicidal IdeationDyskinesia
Myofascial Pain SyndromePulmonary EmbolismVomitingHot FlushNightmare
GerdJoint SwellingPyrexiaPalpitationsAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Savella and Neurontin
- group for people who take Neurontin
- group for people who take Savella

Comments from related studies:

  • From this study (6 months ago):

  • diagnosis of fibromyalgia x 2 years ago
    diagnosis of breast cancer 3 mos ago . No longer taking estrogen progesterone Blood pressure has begun to rise approx 3 mos ago.

    Reply

  • From this study (11 months ago):

  • I have become increasingly obsessive. I was switched to generic Geodon and it was not working. I have been on 60 mg of Geodon for about a month. I am feeling somewhat better ], but still worry a lot.

    Reply

  • From this study (1 year ago):

  • Please help if you are able.
    Background: Very Healthy, active 115 lb. 70 year old female. Worked out, lifted weights, 40 minute walk, 40 deep knee bends, 20 push ups, all daily activities until 8 months ago when became profoundly fatigued, with severe (incapacitating) muscle pain, literally overnight. Had to quit job, as too fatigued to work. Currently: No muscle pain. Debilitating fatigue persists.
    Current Meds:
    200 Tramadol daily, Chronic Severe Bursitis
    8 mgs. Prednisone daily, fatigue
    50 mcs. Synthroid daily, Hypothyroidism
    300 mgs. Gabapentin daily, Post Herpetic Neuralgia (Shingles)
    Savella Dose pack prescribed. Details below.

    Current Problem:
    Recently prescribed Savella dose pack to treat unremitting fatigue. Dx: PMR NOS. Also taking Tramadol 200 mgs. daily, 3 years for Severe Chronic Bursitis.
    After 12.5 msg Savella twice daily for three days, nothing different noted.
    Dose pack increase: 25 mgs twice daily for four days. After three days, noted moderate increase in energy. Dose pack increase to 50 mgs. twice daily. After three to four days felt increasingly worse: fatigued, weak, unsteady on my feet, heart rate 104 (typically 70-74). Fatigue much worse than before started Savella. Quit Savella.
    Question: I read Savella interacts badly with Tramadol, but how seriously for my body, and at what dose? Savella at lower dose (25 mgs twice daily,) was such a welcome therapeutic difference in fatigue symptoms. If possible, would like to restart Savella at 25 mgs twice daily. Would I notice if an interaction with Tramadol at that dose of Savella, and would it preclude taking them together? Looking forward to your report on others experiencing these interactions and symptoms.

    Reply

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More reviews for: Neurontin, Savella

Complete drug side effects:

On eHealthMe, Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Neurontin (gabapentin) is often used to treat neuralgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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