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Review: Savella and Neurontin

This review analyzes the effectiveness and drug interactions between Savella and Neurontin. It is created by eHealthMe based on 236 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 6, 2014: 236 people who reported to have interactions when taking Savella, Neurontin are studied

Trend of Savella, Neurontin's drug interactions, side effects and effectiveness reports (5413537)

Drug combinations in study:
- Savella (milnacipran hydrochloride)
- Neurontin (gabapentin)

eHealthMe real world results:

Most common interactions experienced by people in the use of Savella, Neurontin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Fatigue (feeling of tiredness)97
Hypertension (high blood pressure)86
Nausea (feeling of having an urge to vomit)85
Pain78
Vomiting75
Headache (pain in head)75
Insomnia (sleeplessness)60
Drug Ineffective56
Agitation (state of anxiety or nervous excitement)54
Malaise (a feeling of general discomfort or uneasiness)50

Most common interactions experienced by people in long term use of Savella, Neurontin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Somnolence (a state of near-sleep, a strong desire for sleep)12
Pain10
Drug Ineffective10
Nausea (feeling of having an urge to vomit)9
Tremor (trembling or shaking movements in one or more parts of your body)8
Loss Of Consciousness8
Malaise (a feeling of general discomfort or uneasiness)8
Suicidal Ideation8
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)8
Cardiac Disorder8

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Savella0.00%0.00%72.73%27.27%0.00%
Neurontin0.00%50.00%50.00%0.00%0.00%

Top conditions involved for these people * :

  1. Fibromyalgia
  2. Pain
  3. Depression
  4. Convulsion
  5. Rheumatoid arthritis

Top co-used drugs for these people * :

  1. Nexium
  2. Lyrica
  3. Singulair
  4. Xanax
  5. Ambien

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Neurontin, Savella

You can also:

Complete drug side effects:

On eHealthMe, Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Neurontin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • diagnosis of fibromyalgia x 2 years ago
    diagnosis of breast cancer 3 mos ago . No longer taking estrogen progesterone Blood pressure has begun to rise approx 3 mos ago.

    Reply

  • From this study (6 months ago):

  • I have become increasingly obsessive. I was switched to generic Geodon and it was not working. I have been on 60 mg of Geodon for about a month. I am feeling somewhat better ], but still worry a lot.

    Reply

  • From this study (13 months ago):

  • Please help if you are able.
    Background: Very Healthy, active 115 lb. 70 year old female. Worked out, lifted weights, 40 minute walk, 40 deep knee bends, 20 push ups, all daily activities until 8 months ago when became profoundly fatigued, with severe (incapacitating) muscle pain, literally overnight. Had to quit job, as too fatigued to work. Currently: No muscle pain. Debilitating fatigue persists.
    Current Meds:
    200 Tramadol daily, Chronic Severe Bursitis
    8 mgs. Prednisone daily, fatigue
    50 mcs. Synthroid daily, Hypothyroidism
    300 mgs. Gabapentin daily, Post Herpetic Neuralgia (Shingles)
    Savella Dose pack prescribed. Details below.

    Current Problem:
    Recently prescribed Savella dose pack to treat unremitting fatigue. Dx: PMR NOS. Also taking Tramadol 200 mgs. daily, 3 years for Severe Chronic Bursitis.
    After 12.5 msg Savella twice daily for three days, nothing different noted.
    Dose pack increase: 25 mgs twice daily for four days. After three days, noted moderate increase in energy. Dose pack increase to 50 mgs. twice daily. After three to four days felt increasingly worse: fatigued, weak, unsteady on my feet, heart rate 104 (typically 70-74). Fatigue much worse than before started Savella. Quit Savella.
    Question: I read Savella interacts badly with Tramadol, but how seriously for my body, and at what dose? Savella at lower dose (25 mgs twice daily,) was such a welcome therapeutic difference in fatigue symptoms. If possible, would like to restart Savella at 25 mgs twice daily. Would I notice if an interaction with Tramadol at that dose of Savella, and would it preclude taking them together? Looking forward to your report on others experiencing these interactions and symptoms.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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