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Review: Savella and Neurontin





Summary: drug interactions are reported among people who take Savella and Neurontin together.

This review analyzes the effectiveness and drug interactions between Savella and Neurontin. It is created by eHealthMe based on reports of 263 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Savella and Neurontin >>>

What are the drugs

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,389 users)

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. (latest outcomes from Neurontin 57,763 users)

On Nov, 29, 2014: 263 people who take Savella, Neurontin are studied

Savella, Neurontin outcomes

Drug combinations in study:
- Savella (milnacipran hydrochloride)
- Neurontin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Savella is effective50.00%
(1 of 2 people)
0.00%
(0 of 12 people)
20.00%
(1 of 5 people)
60.00%
(3 of 5 people)
100.00%
(3 of 3 people)
n/an/an/a
Neurontin is effective100.00%
(1 of 1 people)
25.00%
(2 of 8 people)
0.00%
(0 of 2 people)
40.00%
(2 of 5 people)
27.27%
(3 of 11 people)
33.33%
(1 of 3 people)
n/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FatigueHypertensionNeuromaSuicidal IdeationFacet Joint SyndromeDepression Aggravatedn/aFatigue
AgitationNauseaSkin PlaqueNauseaMigraineNausea AggravatedPain
NauseaExhaustion, Fatigue, Lethargy, Tiredness, WearinessSeromaMusculoskeletal StiffnessFibromyalgiaIbsNausea
HeadacheFatigueStevens-johnson SyndromeTremorBack Pain - LowMiddle InsomniaHeadache
InsomniaDecreased AppetitePancreatitisPainDepressionPainAgitation
HyperhidrosisDyspnoeaCervicogenic HeadacheLoss Of ConsciousnessHigh Blood Cholesterol And TriglyceridesDrug IneffectiveInsomnia
DiarrhoeaVentricular HypertrophyExhaustion, Fatigue, Lethargy, Tiredness, WearinessSomnolenceGerdDry MouthDrug Ineffective
IrritabilityNeck PainMuscle FatigueDrug IneffectiveMyofascial Pain SyndromeFatigueVomiting
PalpitationsAbnormal DreamsUrinary RetentionCardiac DisorderHypertensionDecreased AppetiteDiarrhoea
Drug IneffectiveDiastolic DysfunctionHigh Blood PressureMalaiseUrinary RetentionIrritability

Drug effectiveness by gender :

FemaleMale
Savella is effective33.33%
(8 of 24 people)
0.00%
(0 of 3 people)
Neurontin is effective29.63%
(8 of 27 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
FatigueArthralgia
NauseaPain In Extremity
PainDry Mouth
HeadachePain
InsomniaParaesthesia
AgitationRed Blood Cell Sedimentation Rate Increased
Drug IneffectiveDrug Ineffective
VomitingMobility Decreased
DiarrhoeaAntinuclear Antibody Increased
MalaiseWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Savella is effectiven/an/an/a16.67%
(1 of 6 people)
20.00%
(2 of 10 people)
9.38%
(3 of 32 people)
0.00%
(0 of 2 people)
25.00%
(2 of 8 people)
Neurontin is effectiven/an/an/a0.00%
(0 of 6 people)
10.00%
(1 of 10 people)
12.12%
(4 of 33 people)
25.00%
(1 of 4 people)
37.50%
(3 of 8 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aHypertensionDeep Vein ThrombosisTachycardiaNauseaFatigueHeadache
FatigueNauseaCellulitisPainNauseaInsomnia
RashDiarrhoeaHyperhidrosisAgitationHeadacheBurning Sensation
FlushingVomitingExhaustion, Fatigue, Lethargy, Tiredness, WearinessDecreased AppetiteHeart Rate IncreasedFatigue
Lupus-like SyndromeRashNauseaMigraineMalaiseDiarrhoea
PainNeuropathy PeripheralFallDyspnoeaAgitation
InjuryLoss Of ConsciousnessArthralgiaPainPain
Back Pain - LowDyspnoeaHeadacheSuicidal IdeationDyskinesia
Myofascial Pain SyndromePulmonary EmbolismVomitingHot FlushNightmare
GerdJoint SwellingPyrexiaPalpitationsAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Savella and Neurontin?

You are not alone! Join a related mobile support group:
- support group for people who take Savella and Neurontin
- support group for people who take Neurontin
- support group for people who take Savella

Can you answer these questions (Ask a question):

  • Requip cause dysphagia
    an increase caused me not to be able to swallow at all
  • Does anyone else have peripheral neuropathy? anyone have pn with lichen sclerosus? i have pain in hands, feet and face.
    Pain much worse at end of day and when I overdo. Sleep difficult - but essential! Feel so much better if I get 6+ hours. At the moment, very distressed by swollen lips (mostly inside mouth) and tissue surrounding eyes. I'm sure I have some arthritis in my fingers and toes. I also have had lichen sclerosus on my skin for nearly 20 years. Have had the PN for 15 years or so. I'm afraid that the medications can actually make the condition worse. If anyone has any suggestions, I'm all ears!
  • Does nexplanon have nickel in it?
    I have a severe nickel allergy and I have epilepsy. I am considering explain to reduce periodes since my seizures are worse that time of the month. I need to know if nexplanon has nickel because I need to avoid it if it does.
  • Can gabapentin cause bladder distension? there is no urinary symptom .
    Existing illness are Chronic renal failure (after hydro uretero nephrosis due to BPH) and peripheral neuropathy (vit B6 deficiency ) after ATT are the major problems along with BP .At present , the problem is that creatinine gas risen from 1,1 to 1.5 in 6 months .Since 6 months , I am taking medicines for neuropathy so I doubt some side effect of these medicines as Ultrasound has shown bladder distension but I do not feel any urinary problem at present. I also have kidney stones but seeing the ultrasound report , doctor said it is not hindering with urine passage . I feel some tightness , fullness and protruded lower abdomen part. I am aged 72 from India and am vegetarian.I also take some drugs for controlling blood pressure . I have elevated Blood urea at present (52) . I was given medicine to relax prostrate muscles for last 20 days but I did not feel any improvement in my bladder size. I had had my prostrate operated 2 years back.
  • Did anyone stop losing hair after being off gabapentin?
    I had been taking gabapentin for interstitial cystitis. I had only been on it for 5 months and a couple of months in I noticed everytime I took a shower tons of hair was coming out and when ever I ran my fingers through my hair I always had a lot of hair come out then too. It has become very dry and brittle and breaks easily. I wish I never took this medication. I have been off of it for 2 weeks and I am still losing hair. I was wondering if anyone after being off this medication stopped losing hair and if new hair started growing back.

More questions for: Neurontin, Savella

You may be interested at these reviews (Write a review):

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  • Drug interractions savella. amoxicillin
    Sudden ache, pain and neuropathy in right hand and wrist within 8 hours of sterting Amoxicillin.
  • Cough and gabapentin
    Have chronic cough for 6 yr's at least.3 yr's ago it got bad enough to seek doc. Help. Took all the tests . Tried to tell me I had asthma,copd, ect. Put me on sprivia, symbicort, singular, helped a little for awhile. Long story short. Went to one doc. He asked me some questions about my cough. Figured out it usually started with a tickle on the left side of my throat. And he put me on gabapentin 300mg. 3 times Aday. Which is for nerve damage. It took about 7days to see some change. And about 35days To stop the chronic cough. I still cough once in awhile. But no chronic coughing. Now I am going to try and see if I can stop the other med,s one at a time and see what happens
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Nausea and vomiting while taking savella
    I have been on Savella for 6 months now and the nausea has increased with time and now I also have vomiting daily along with occasional diarrhea. I am currently weaning off of the Savella, cutting the dosage in half for two weeks and then one pill every other day for two weeks, following my dr.'s instructions. I have three weeks total left and still have the nausea and vomiting but hopeful that these will start to go away soon. Anyone else who has weaned off of it- how long until your symptoms subsided?

More reviews for: Neurontin, Savella

Comments from related studies:

  • From this study (10 months ago):

  • diagnosis of fibromyalgia x 2 years ago
    diagnosis of breast cancer 3 mos ago . No longer taking estrogen progesterone Blood pressure has begun to rise approx 3 mos ago.

    Reply

  • From this study (1 year ago):

  • I have become increasingly obsessive. I was switched to generic Geodon and it was not working. I have been on 60 mg of Geodon for about a month. I am feeling somewhat better ], but still worry a lot.

    Reply

  • From this study (2 years ago):

  • Please help if you are able.
    Background: Very Healthy, active 115 lb. 70 year old female. Worked out, lifted weights, 40 minute walk, 40 deep knee bends, 20 push ups, all daily activities until 8 months ago when became profoundly fatigued, with severe (incapacitating) muscle pain, literally overnight. Had to quit job, as too fatigued to work. Currently: No muscle pain. Debilitating fatigue persists.
    Current Meds:
    200 Tramadol daily, Chronic Severe Bursitis
    8 mgs. Prednisone daily, fatigue
    50 mcs. Synthroid daily, Hypothyroidism
    300 mgs. Gabapentin daily, Post Herpetic Neuralgia (Shingles)
    Savella Dose pack prescribed. Details below.

    Current Problem:
    Recently prescribed Savella dose pack to treat unremitting fatigue. Dx: PMR NOS. Also taking Tramadol 200 mgs. daily, 3 years for Severe Chronic Bursitis.
    After 12.5 msg Savella twice daily for three days, nothing different noted.
    Dose pack increase: 25 mgs twice daily for four days. After three days, noted moderate increase in energy. Dose pack increase to 50 mgs. twice daily. After three to four days felt increasingly worse: fatigued, weak, unsteady on my feet, heart rate 104 (typically 70-74). Fatigue much worse than before started Savella. Quit Savella.
    Question: I read Savella interacts badly with Tramadol, but how seriously for my body, and at what dose? Savella at lower dose (25 mgs twice daily,) was such a welcome therapeutic difference in fatigue symptoms. If possible, would like to restart Savella at 25 mgs twice daily. Would I notice if an interaction with Tramadol at that dose of Savella, and would it preclude taking them together? Looking forward to your report on others experiencing these interactions and symptoms.

    Reply

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Complete drug side effects:

On eHealthMe, Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Neurontin (gabapentin) is often used to treat neuralgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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