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Review: Methotrexate and Niacin





Summary: drug interactions are reported among people who take Methotrexate and Niacin together.

This review analyzes the effectiveness and drug interactions between Methotrexate and Niacin. It is created by eHealthMe based on reports of 320 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methotrexate and Niacin >>>

What are the drugs

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. (latest outcomes from Niacin 6,312 users)

On Nov, 28, 2014: 320 people who take Methotrexate, Niacin are studied

Methotrexate, Niacin outcomes

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Niacin (niacin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methotrexate is effectiven/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
100.00%
(2 of 2 people)
n/an/a
Niacin is effectiven/a0.00%
(0 of 1 people)
n/a50.00%
(1 of 2 people)
0.00%
(0 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FlushingFlushingSinusitisPruritusPruritus GeneralisedRetinal Artery Occlusionn/aFlushing
VomitingBurning SensationPyrexiaFlushingRashCerebral Artery EmbolismFall
PruritusPruritusSinus CongestionRheumatoid ArthritisOsteolysisAtrial Septal DefectPruritus
RetchingImpatienceNasopharyngitisErythemaHepatitisDizziness PosturalDizziness
Burning SensationPain Of SkinNasal CongestionBreast CancerHeadacheAnaemiaNausea
Abdominal PainIrritabilityHeadacheRashErectile DysfunctionDuodenal UlcerDiarrhoea
Muscle SpasmsRashSyncopeTachycardiaDyspnoea
StomatitisDiarrhoeaMalaiseIntestinal UlcerMyalgia
Skin Burning SensationFearInsomniaHaemodynamic InstabilityVomiting
NauseaAstheniaC-reactive Protein IncreasedMalaiseDrug Ineffective

Drug effectiveness by gender :

FemaleMale
Methotrexate is effective66.67%
(2 of 3 people)
66.67%
(2 of 3 people)
Niacin is effective50.00%
(1 of 2 people)
0.00%
(0 of 3 people)

Most common drug interactions by gender * :

FemaleMale
FlushingFlushing
FallDrug Ineffective
Back PainPruritus
DiarrhoeaPain In Extremity
DyspnoeaCellulitis
CoughNausea
HeadacheFeeling Hot
Road Traffic AccidentInjection Site Haematoma
MyalgiaBlood Glucose Increased
PruritusDizziness

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methotrexate is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
40.00%
(2 of 5 people)
100.00%
(2 of 2 people)
Niacin is effectiven/an/an/an/an/an/a0.00%
(0 of 5 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/an/aVomitingInjection Site PainFlushingFlushing
DiarrhoeaFeeling HotDrug IneffectivePain
DizzinessInjection Site HaemorrhagePruritusDrug Ineffective
MenopauseAbdominal PainPain In ExtremityPruritus
Meniscus LesionStomatitisPulmonary TuberculosisFall
Mechanical UrticariaRetchingDry SkinBack Pain
BursitisVomitingDizzinessOedema Peripheral
Breast PainMuscle SpasmsChest PainCellulitis
Morton's NeuromaInjection Site HaematomaB-cell LymphomaRash
MononeuropathyErythemaStomatitisTooth Extraction

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Niacin?

You are not alone! Join a related mobile support group:
- support group for people who take Methotrexate and Niacin
- support group for people who take Methotrexate
- support group for people who take Niacin

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Could pemphigoid cause my pet scan to lite up?
    I recently had a PET scan to look at mass on my lungs. The Doc called me today & said the scan lit up. What are some reasons for it to lite up other than cancer? I have Pemphigoid. Could this be a reason?
  • Is it safe to take both at the same time
    tom had stents placed 1 1/2 ago ,,,,was only on Amlodipine Besylate 10 mg 1x a day ......and plavix and Ranitdine for heartburn... He just went to the DR and they told him to take losartan 1 time a day 50mg....Tom thought they said liptor ,,,,I recalling the Dr to make sure since I was not there at the time of this visit ,,,,,any suggestions if both high blood pressure med's are taken at the same time
  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks

More questions for: Methotrexate, Niacin

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

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    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
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More reviews for: Methotrexate, Niacin

Comments from related studies:

  • From this study (3 years ago):

  • Any side effects that a drug may have he is subject to and usually will have the side effects....Actos made him gain about 1 lb a day and Byetta made him lose over 100 pounds once he started it.

    Reply

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Niacin (niacin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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