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Review: taking Norco and Xanax together

Summary: drug interactions are reported among people who take Norco and Xanax together.

This review analyzes the effectiveness and drug interactions between Norco and Xanax. It is created by eHealthMe based on reports of 10,142 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 30, 2015: 10,142 people who take Norco, Xanax are studied

Norco, Xanax outcomes

Drug combinations in study:
- Norco (acetaminophen; hydrocodone bitartrate)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Norco is effective32.86%
(23 of 70 people)
(24 of 55 people)
(10 of 26 people)
(41 of 74 people)
(29 of 91 people)
(34 of 73 people)
(11 of 33 people)
(2 of 9 people)
Xanax is effective34.00%
(17 of 50 people)
(18 of 55 people)
(21 of 49 people)
(33 of 61 people)
(32 of 81 people)
(48 of 69 people)
(40 of 53 people)
(5 of 8 people)

Drug effectiveness by gender :

Norco is effective40.87%
(132 of 323 people)
(42 of 107 people)
Xanax is effective53.94%
(171 of 317 people)
(41 of 107 people)

Drug effectiveness by age :

Norco is effective0.00%
(0 of 1 people)
(0 of 4 people)
(27 of 122 people)
(53 of 209 people)
(40 of 221 people)
(32 of 163 people)
(22 of 91 people)
Xanax is effective0.00%
(0 of 1 people)
(2 of 4 people)
(24 of 123 people)
(65 of 210 people)
(56 of 219 people)
(44 of 166 people)
(22 of 81 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainHypotensionCholecystitis ChronicDepressionDepressionDepressionAnxietyPain
Suicide AttemptAstheniaNauseaVentricular Septal DefectInsomniaInsomniaPainNausea
HypoxiaDizzinessVomitingDrug Exposure During PregnancyConstipationPainDepressionDepression
AnxietyCholecystitis ChronicAbdominal PainObstructive Airways DisorderSuicide AttemptHeadacheNauseaDyspnoea
ConstipationAnxietyAnxietyPulmonary HypertensionRoad Traffic AccidentEmotional DistressSuicidal IdeationBack Pain
Drug IneffectivePulmonary EmbolismGallbladder InjuryHeadacheRenal FailureSuicide AttemptDrug DependenceFatigue
DiarrhoeaPainHydronephrosisPainPainConvulsionIntentional OverdoseHeadache
Memory ImpairmentDyspnoeaPyelonephritisHypotensionHallucinationChest PainAbdominal PainInsomnia
InsomniaGrand Mal ConvulsionMuscle SpasmsHypertensionHeadacheNauseaArthralgiaVomiting

Most common drug interactions by gender * :

Back PainHeadache
FatigueBack Pain
ArthralgiaDrug Dependence

Most common drug interactions by age * :

Diabetes Mellitusn/aDrug AbuseCompleted SuicideAnxietyAnxietyPainAnxiety
DeathCholecystitis ChronicPainNauseaDepressionAnxietyPain
Cardiac ArrestRespiratory ArrestDepressionPainNauseaDyspnoea
Respiratory ArrestAnxietyPainNauseaDepressionNausea
PainNauseaDrug DependenceHeadacheDyspnoeaAsthenia
Cardio-respiratory ArrestCardiac ArrestArthralgiaInsomniaArthralgiaDizziness
Accidental OverdoseCardio-respiratory ArrestInsomniaBack PainBack PainFatigue
DiarrhoeaHeadacheBack PainDyspnoeaInsomniaBack Pain
VomitingVomitingChest PainChest PainFallDepression
AnxietyDrug AbuseHeadacheFatigueChest PainVomiting

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Norco
- support group for people who take Xanax

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Norco (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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