eHealthMe - Personalized health information eHealthMe - Personalized health information

Personalized health information

All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Check symptoms  -  Ask a question  -  Write a review  -  Studies  -  Answered/ Unanswered  -  Reviews

Review: taking Nortriptyline and Zyban together

Summary: drug interactions are reported among people who take Nortriptyline and Zyban together. This review analyzes the effectiveness and drug interactions between Nortriptyline and Zyban. It is created by eHealthMe based on reports of 519 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


You are not alone: join a support group for people who take Nortriptyline and Zyban >>>

What are the drugs

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in depression. (latest outcomes from 1,515 Nortriptyline hydrochloride users)

Zyban has active ingredients of bupropion hydrochloride. It is often used in quit smoking. (latest outcomes from 7,089 Zyban users)

On Apr, 25, 2015: 519 people who take Nortriptyline Hydrochloride, Zyban are studied

Nortriptyline Hydrochloride, Zyban outcomes

Drug combinations in study:
- Nortriptyline Hydrochloride (nortriptyline hydrochloride)
- Zyban (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Nortriptyline Hydrochloride is effective0.00%
(0 of 4 people)
(0 of 2 people)
(2 of 7 people)
(2 of 6 people)
(1 of 5 people)
(3 of 5 people)
(2 of 4 people)
(1 of 1 people)
Zyban is effective0.00%
(0 of 2 people)
(1 of 4 people)
(0 of 5 people)
(2 of 9 people)
(4 of 10 people)
(3 of 5 people)
(2 of 2 people)
(0 of 1 people)

Drug effectiveness by gender :

Nortriptyline Hydrochloride is effective34.62%
(9 of 26 people)
(2 of 8 people)
Zyban is effective32.14%
(9 of 28 people)
(3 of 10 people)

Drug effectiveness by age :

Nortriptyline Hydrochloride is effectiven/an/an/a33.33%
(2 of 6 people)
(2 of 10 people)
(2 of 11 people)
(3 of 6 people)
(2 of 8 people)
Zyban is effectiven/an/an/a28.57%
(2 of 7 people)
(1 of 12 people)
(3 of 11 people)
(3 of 7 people)
(3 of 8 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DehydrationDrug IneffectiveSuicidal IdeationNeuropathy PeripheralAbdominal PainSuicide AttemptTinnitusPain
DysarthriaDrug Withdrawal SyndromeRash ErythematousType 2 Diabetes MellitusCholelithiasisDepressionNauseaAnxiety
Emotional DistressTherapeutic Response DecreasedNeuropathy PeripheralDiabetes MellitusCholecystitis ChronicIntentional OverdoseVertigoDepression
InsomniaGrand Mal ConvulsionHyperglycaemiaSuicidal IdeationEmotional DistressAnxietyHypoaesthesia
Cerebral IschaemiaMultiple SclerosisDiabetes MellitusHyperglycaemiaInjuryAngerArthralgia
Electrocardiogram Qrs Complex ProlongedSubstance AbuseHerniaHerniaAnxietyAmnesiaWeight Increased
Electrocardiogram T Wave PeakedDrug DependenceSkin UlcerLiver DisorderPainAggressionParaesthesia
Electroencephalogram AbnormalConstipationType 2 Diabetes MellitusFatigueNauseaAbnormal BehaviourBack Pain
Family StressGenital DischargeImpaired HealingInguinal HerniaBlurred VisionGrand Mal ConvulsionDiarrhoea
AnorexiaTirednessScarBlurred VisionNumbness In Hands Or FeetMiscarriageSpinal Osteoarthritis

Most common drug interactions by gender * :

Weight IncreasedHypoaesthesia
HypoaesthesiaType 2 Diabetes Mellitus
Back PainFatigue
Spinal OsteoarthritisPain In Extremity
OsteomyelitisSuicidal Ideation

Most common drug interactions by age * :

Type 2 Diabetes MellitusSudden DeathAgitationAnxietyDepressionDepressionPainOedema Peripheral
Suicide AttemptSomnolenceEmotional DistressBack PainAnxietyAnxietyDrug Ineffective
Hepatitis CDisturbance In AttentionHypoaesthesiaPainPainDiarrhoeaDyspnoea
HaematocheziaFatigueWeight IncreasedParaesthesiaType 2 Diabetes MellitusParaesthesiaThrombosis
FallInfluenzaConstipationPyrexiaFatigueHypoaesthesiaNeuropathy Peripheral
DeafnessFatigueAnxietyChest PainArthralgiaHypoaesthesia
Memory ImpairmentFallHypoaesthesiaNauseaNeuropathy PeripheralArthritis
Muscle SpasmsMuscle SpasmsPain In JawAstheniaGeneral Physical Health DeteriorationCoronary Artery Disease
Drug IneffectiveSedationFatigueBlood Cholesterol IncreasedLymphadenopathyArthralgia
Rectal HaemorrhageDrug DependenceWeight IncreasedWeight IncreasedErythemaBone Disorder

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Nortriptyline and Zyban on

Do you take Nortriptyline and Zyban?


You are not alone! Join a related support group:
- support group for people who take Nortriptyline Hydrochloride
- support group for people who take Zyban

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Nortriptyline Hydrochloride, Zyban

You may be interested at these reviews (Write a review):

  • Prozac and benztropin
    My son was on Prozac for two years, and it seemed to work very well. He was glad he was on it. In February he was prescribed Benztropin. 18 days later, he killed himself. He didn't eat or sleep his last few days, we found out later. He was not right.
  • Lamotrigine severe rash
    I started taking 100mg of Teva-Lamotrigine Nov 22 once daily. I got a refill on Dec 5 that was Mylan-Lamotrigine. Two days later I woke up with an odd hot feeling rash all over my body and severe fatigue. I went back to bed 1/2 hour later after taking my regular Wellbutrin and the Lamotrigine. I wok ...
  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to ...
  • Librium 25mg and wellbutrin 300mg for >1 month
    I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.
  • Bedwetting with paxil and wellbutrin
    I have been using both of these drugs and now have bedwetting issues 5 times a week on average. I would rate the bedwetting as moderate about a6/10 but my wife and I can live with this as she had made the comment " you are back to the man I married ". I started taking these due to depression about ...

More reviews for: Nortriptyline Hydrochloride, Zyban

Comments from related studies:

  • From this study (2 years ago):

  • have been having a high resting heart rate (over 100) and with just small amounts of physical activity it jumps high. I spent 10 minutes on the treadmill and it climbed to 180. I am 54 years old and just slightly overweight around the middle. I feel tired and weak when this happens but anxious. I can feel the pulse in my neck jumping. I've had a cardiac stress test and ultrasound and there is nothing wrong with my heart. I think it may be be one of the medications I'm on. Synthroid is most recent. Could it be that?


  • From this study (5 years ago):

  • Every year in January I try and get off each of the medications, one at a time and the symptoms come back and I have to start taking them again.


Complete drug side effects:

On eHealthMe, Nortriptyline Hydrochloride (nortriptyline hydrochloride) is often used to treat migraine. Zyban (bupropion hydrochloride) is often used to treat quit smoking. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.