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Review: taking Novolog and Humalog Kwikpen together

Summary: drug interactions are reported among people who take Novolog and Humalog Kwikpen together.

This review analyzes the effectiveness and drug interactions between Novolog and Humalog Kwikpen. It is created by eHealthMe based on reports of 761 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Novolog and Humalog Kwikpen >>>

What are the drugs

Novolog has active ingredients of insulin aspart recombinant. It is often used in type 1 diabetes. (latest outcomes from 12,331 Novolog users)

Humalog kwikpen has active ingredients of insulin lispro recombinant. It is often used in type 1 diabetes. (latest outcomes from 68 Humalog kwikpen users)

On Mar, 1, 2015: 761 people who take Novolog, Humalog Kwikpen are studied

Novolog, Humalog Kwikpen outcomes

Drug combinations in study:
- Novolog (insulin aspart recombinant)
- Humalog Kwikpen (insulin lispro recombinant)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Novolog is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
Humalog Kwikpen is effectiven/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

Novolog is effectiven/a0.00%
(0 of 1 people)
Humalog Kwikpen is effectiven/a0.00%
(0 of 1 people)

Drug effectiveness by age :

Novolog is effectiven/a0.00%
(0 of 1 people)
Humalog Kwikpen is effectiven/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypoglycaemiaHypoglycaemiaAnti-insulin Antibody IncreasedHypoglycaemiaHyperglycaemiaBlood Glucose IncreasedSomnolenceBlood Glucose Increased
Non-cardiac Chest PainDiabetes Mellitus Inadequate ControlHyperglycaemiaHyperglycaemiaHypoglycaemiaMalaiseGastrointestinal HaemorrhageBlood Glucose Decreased
Diabetes Mellitus Inadequate ControlHepatic Function AbnormalAnti-insulin Antibody PositiveAnti-insulin Antibody PositiveAnti-insulin Antibody IncreasedBlood Glucose FluctuationHaemoglobin DecreasedNausea
Anti-insulin Antibody PositiveAnti-insulin Antibody IncreasedInsulin ResistanceNauseaDiabetes Mellitus Inadequate ControlVaginal MycosisSomnambulismHypoglycaemia
Renal Failure AcuteAnti-insulin Antibody PositiveHypoglycaemiaPiloerectionAnti-insulin Antibody PositiveBlood Glucose DecreasedInitial InsomniaDizziness
AsthmaInsulin ResistanceInjection Site IndurationPancreatitisBlood Glucose IncreasedShock HypoglycaemicDrug IneffectiveDyspnoea
Suicidal IdeationInjection Site ErythemaInjection Site PainDiabetic NephropathyInsulin ResistanceAstheniaDiabetes Mellitus Inadequate Control
HyperglycaemiaInjection Site PruritusInjection Site ErythemaDiabetic NeuropathyOedema PeripheralConvulsionAnxiety
Abdominal PainAlanine Aminotransferase IncreasedDrug HypersensitivityAnti-insulin Antibody IncreasedInjection Site ErythemaDepressed Level Of ConsciousnessPain
Blood Glucose IncreasedInjection Site ReactionInjection Site PruritusBlood Creatine Phosphokinase IncreasedNauseaNauseaDrug Ineffective

Most common drug interactions by gender * :

Blood Glucose IncreasedBlood Glucose Increased
Blood Glucose DecreasedDiabetes Mellitus Inadequate Control
DyspnoeaBlood Glucose Decreased
DizzinessAnti-insulin Antibody Positive
Weight DecreasedDrug Ineffective
DehydrationLoss Of Consciousness

Most common drug interactions by age * :

n/aInjection Site ReactionPainBlood Glucose IncreasedBlood Glucose IncreasedBlood Glucose IncreasedBlood Glucose IncreasedBlood Glucose Increased
BiteConvulsionAgitationHeadacheMalaiseDiabetes Mellitus Inadequate ControlHypoglycaemia
Penile SwellingDehydrationTicAnti-insulin Antibody IncreasedDiabetes Mellitus Inadequate ControlHypoglycaemiaBlood Glucose Decreased
Scrotal OedemaHyperglycaemiaAggressionInsulin ResistanceDyspnoeaHyperglycaemiaNausea
Urticaria NosFibula FracturePsychomotor HyperactivityAnaphylactic ReactionAstheniaNauseaWeight Decreased
Angioneurotic OedemaFracture DisplacementBlood Glucose FluctuationPregnancyDizzinessMalaiseCardiac Failure Congestive
UrticariaHemiplegiaUrinary Tract InfectionAstheniaHeadacheDrug IneffectiveHyperglycaemia
Blood Glucose IncreasedFallAnaphylactic ShockHypertensionNauseaDizzinessRenal Failure Acute
FlushingCarotid Artery OcclusionDiabetes Mellitus Inadequate ControlDiabetic KetoacidosisSomnolenceDyspnoeaAnxiety
Rash GeneralisedEmotional DistressAnti-insulin Antibody PositiveHyperglycaemiaCholelithiasisPainHyperhidrosis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Novolog and Humalog Kwikpen on

Do you take Novolog and Humalog Kwikpen?

You are not alone! Join a related mobile support group:
- support group for people who take Novolog and Humalog Kwikpen
- support group for people who take Humalog Kwikpen
- support group for people who take Novolog

Can you answer these questions (Ask a question):

More questions for: Humalog Kwikpen, Novolog

You may be interested at these reviews (Write a review):

  • Thrush while on prograf
    I am a health provider at an emergency room and had a patient come in because of a food bolus and when i examined his oral/pharynx I noticed he had thrush. Patient stated it has been their for a while. Patient also stated he has been having progressive difficulty in swallowing. Pt is a kidney transplant patient and has been worked up for other causes of his thrush (including HIV, as per patient results neg) and everything came back negative. I can only conclude that maybe the prograf which is a immunosupressent can possible be the cause
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.

More reviews for: Humalog Kwikpen, Novolog

Complete drug side effects:

On eHealthMe, Novolog (insulin aspart recombinant) is often used to treat type 1 diabetes. Humalog Kwikpen (insulin lispro recombinant) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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