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Review: Novolog and Levemir

This review analyzes the effectiveness and drug interactions between Novolog and Levemir. It is created by eHealthMe based on reports of 2,257 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Novolog and Levemir >>>

What are the drugs

Novolog (latest outcomes from 12,318 users) has active ingredients of insulin aspart recombinant. It is often used in diabetes.

Levemir (latest outcomes from 7,477 users) has active ingredients of insulin detemir recombinant. It is often used in diabetes.

On Jul, 13, 2014: 2,257 people who take Novolog, Levemir are studied

Novolog, Levemir outcomes

Drug combinations in study:
- Novolog (insulin aspart recombinant)
- Levemir (insulin detemir recombinant)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Novolog is effective0.00%
(0 of 2 people)
(5 of 7 people)
(1 of 1 people)
(1 of 2 people)
(5 of 8 people)
(5 of 6 people)
(1 of 2 people)
(1 of 1 people)
Levemir is effective100.00%
(1 of 1 people)
(5 of 9 people)
(1 of 1 people)
(2 of 5 people)
(4 of 8 people)
(3 of 3 people)
(0 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypoglycaemiaBlood Glucose IncreasedHypoglycaemiaBlood Glucose IncreasedDiabetes Mellitus Inadequate ControlPruritusDiabetic Foot InfectionBlood Glucose Increased
HyperglycaemiaHypoglycaemiaBlood Glucose FluctuationSepsisHypoglycaemiaSwellingConcomitant Disease ProgressionHypoglycaemia
Blood Glucose IncreasedHyperglycaemiaDiabetes Mellitus Inadequate ControlHyperglycaemiaBlood Glucose IncreasedErythemaInfectionNausea
Diabetes Mellitus Inadequate ControlDiabetes Mellitus Inadequate ControlPruritusBradycardiaDrug Exposure During PregnancyFatigueGouty ArthritisBlood Glucose Decreased
Intentional OverdoseAnti-insulin Antibody IncreasedDizzinessCardiac ArrestAnti-insulin Antibody PositiveInjection Site PainMood SwingsDrug Exposure During Pregnancy
Blood Glucose DecreasedAnti-insulin Antibody PositiveBlood Glucose IncreasedHypoglycaemiaHyperglycaemiaBlood Glucose IncreasedNeoplasm MalignantDiabetes Mellitus Inadequate Control
UrticariaPetit Mal EpilepsyJaundice NeonatalDiabetic GangreneMalaiseHypersensitivityUrticariaPneumonia
Anti-insulin Antibody IncreasedDiabetic KetoacidosisOedema PeripheralBlood Glucose FluctuationHypersensitivityDeathAngerVomiting
DyspnoeaBlood Glucose FluctuationCytolytic HepatitisDiabetic NeuropathyFatigueMalaiseGouty TophusDyspnoea
Drug HypersensitivitySensory DisturbanceDrug Exposure During PregnancyAmnesiaDrug EruptionInjection Site IrritationBlood Glucose IncreasedBlood Glucose Fluctuation

Drug effectiveness by gender :

Novolog is effective65.00%
(13 of 20 people)
(6 of 9 people)
Levemir is effective60.00%
(12 of 20 people)
(4 of 9 people)

Most common drug interactions by gender * :

Blood Glucose IncreasedBlood Glucose Increased
Blood Glucose DecreasedNausea
Drug Exposure During PregnancyDiabetes Mellitus Inadequate Control
Oedema PeripheralBlood Glucose Fluctuation
Diabetes Mellitus Inadequate ControlDehydration
RashBlood Glucose Decreased

Drug effectiveness by age :

Novolog is effectiven/an/a100.00%
(1 of 1 people)
(4 of 4 people)
(1 of 1 people)
(7 of 11 people)
(4 of 36 people)
(2 of 9 people)
Levemir is effectiven/an/a100.00%
(1 of 1 people)
(4 of 4 people)
(1 of 1 people)
(5 of 11 people)
(3 of 36 people)
(2 of 9 people)

Most common drug interactions by age * :

Hypoglycaemia NeonatalBlood Glucose IncreasedHypoglycaemiaDrug Exposure During PregnancyDiplopiaBlood Glucose IncreasedBlood Glucose IncreasedBlood Glucose Increased
Weight Decrease NeonatalDrug IneffectiveBlood Glucose IncreasedBlood Glucose IncreasedBlood Glucose IncreasedHypoglycaemiaNauseaHypoglycaemia
Feeding Disorder NeonatalIdiopathic Thrombocytopenic PurpuraPruritusHypoglycaemiaDrug Exposure During PregnancyNauseaHypoglycaemiaBlood Glucose Decreased
Jaundice NeonatalErythema MultiformeHyperglycaemiaVitreous HaemorrhageDiabetic KetoacidosisWeight IncreasedBlood Glucose DecreasedPneumonia
Dermatitis DiaperBlood Glucose FluctuationPetit Mal EpilepsyDiabetic KetoacidosisPre-eclampsiaAbortion SpontaneousDiabetes Mellitus Inadequate ControlBlood Glucose Fluctuation
Eczema InfantileInsomniaBlood Glucose FluctuationMaculopathyPregnancyBlood Glucose FluctuationVomitingDyspnoea
Large For Dates BabyGait DisturbanceHypoglycaemic SeizureEczemaInjection Site PainBlood Glucose DecreasedDehydrationDiabetes Mellitus Inadequate Control
Seborrhoeic DermatitisWeight Bearing DifficultyBlood Glucose DecreasedDiabetes Mellitus Inadequate ControlMaternal Exposure During PregnancyDiarrhoeaSepsisRenal Failure Acute
Drug Exposure During PregnancyHypoglycaemiaDiabetic KetoacidosisNauseaHypoglycaemiaAbdominal PainDyspnoeaAsthenia
Blood Glucose DecreasedInjection Site HaemorrhageInjection Site PainVomitingCondition AggravatedOedema PeripheralDizzinessNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Novolog and Levemir
- group for people who take Levemir
- group for people who take Novolog

Comments from related studies:

  • From this study (1 month ago):

  • Vertigo, nausea and deafness seem to come and go. I also get fulness in the ear. With no seemingly causing factor. Was told I had meniers disease. However have now been told I may have auditory neuropathy.


  • From this study (3 months ago):

  • I am experiencing intentional movements when going to sleep. The movements follow what I am dreaming about.


    Liz on May, 2, 2014:

    Tumeric gave me very bad chest pain radiating to my left arm and a migraine at the same time that came on suddenly and left as soon as the chest pain left.

    I tried putting it in milk and got the same reaction.
    I made lamb curry and ate a bit of that and it had tumeric and had the chest pain, sweating, headache.

    I tried putting it in bone broth and got very bad chest pains I went to the emergency room thinking i was having a heart attack.


  • From this study (5 months ago):

  • I started 18 units of levimir in january and my levothyroxine was raised from 112 mg to 125 at the same time. Levimir was raised from 15 to 34 units on feb 4 and since then to 38 units. I started novolog flex pen on feb. 4th. and my levothyroxine was elevated to alternating doses of 125 and 137. Since then I have been to the ER where they did ck test that was 726. The normal reference range is 30-200. My ckmb was4.9 with the normal reference range being 0.1-4.0. I had numbness on my left ear which has not gone away, it was coming and going, but is now more constant. Headaches, dizziness, difficulty breathing, loss of sleep, 3-4 hours a night max, can't catch my breath sitting or laying down, am better off when I'm on my feet,dizziness, fatigue, feels like a pressure or dizziness in both eyes. Have been in contact with endocrinologist and PCP. I stopped Testosterone injections, had my levothyroxine reduced to 112, quit taking novolog and got back on glimeperide, and stopped atorvastatin. Symptoms are not going away. It's been going on since the increases in medicine on feb 4. I had been getting test of ck and ckmb before and they were not high until the change in these medicines. I've been back to my PCP twice and shes trying to tell me it isn't the meds but I know it is. My blood pressure was high this week and that is never the case with me. I have had MRI on the chest and head, a brain scan MRI and carotid artery ultra sound that showed nothing out of the norm. I feel that these medicines are killing me. I can't go on like this much longer. My PCP does not seem to agree. Please advise!


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Complete drug side effects:

On eHealthMe, Novolog (insulin aspart recombinant) is often used to treat diabetes. Levemir (insulin detemir recombinant) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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