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Review: taking NyQuil and Benadryl together

Summary: drug interactions are reported among people who take NyQuil and Benadryl together.

This review analyzes the effectiveness and drug interactions between NyQuil and Benadryl. It is created by eHealthMe based on reports of 112 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take NyQuil and Benadryl >>>

What are the drugs

Nyquil has active ingredients of acetaminophen; dextromethorphan; doxylamine; pseudoephedrine. It is often used in the flu. (latest outcomes from 1,144 Nyquil users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,395 Benadryl users)

On Feb, 10, 2015: 112 people who take NyQuil, Benadryl are studied

NyQuil, Benadryl outcomes

Drug combinations in study:
- NyQuil (acetaminophen; dextromethorphan; doxylamine; pseudoephedrine)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NyQuil is effective0.00%
(0 of 2 people)
0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Benadryl is effective0.00%
(0 of 2 people)
n/a100.00%
(1 of 1 people)
n/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pulmonary EmbolismComplicated MigraineComplicated Migrainen/an/an/an/aEmotional Distress
AbasiaPain Nos
PneumoniaCerebrovascular Accident Nos
HypoxiaBlood Pressure Increased
DyspnoeaAnxiety Nec
Condition AggravatedMental Impairment Nos
ErythemaInjury
UrticariaCardiac Failure Congestive
PruritusDyspnoea
Pain In ExtremityGastrooesophageal Reflux Disease

Drug effectiveness by gender :

FemaleMale
NyQuil is effective0.00%
(0 of 3 people)
n/a
Benadryl is effective33.33%
(1 of 3 people)
n/a

Most common drug interactions by gender * :

FemaleMale
Emotional DistressAnxiety Nec
Pain NosPain Nos
Cerebrovascular Accident NosEmotional Distress
Blood Pressure IncreasedBlood Pressure Increased
Anxiety NecCerebrovascular Accident Nos
Mental Impairment NosCardiac Failure Congestive
Suicide AttemptDyspnoea
AnxietyMental Impairment Nos
General Physical Health DeteriorationHeart Disease Congenital
PainHypospadias

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
NyQuil is effectiven/an/an/a0.00%
(0 of 2 people)
n/a0.00%
(0 of 1 people)
n/an/a
Benadryl is effectiven/an/an/a50.00%
(1 of 2 people)
n/a0.00%
(0 of 1 people)
n/an/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aNauseaNon-accidental OverdosePulmonary EmbolismMiddle InsomniaUterine HaemorrhageCardiac Failure
AnxietySuicide AttemptAnxietyBack DisorderVenous Thrombosis Deep LimbSerotonin Syndrome
ParanoiaHepatic FailureEmotional DistressArthritisDyspnoea NosAcute Pulmonary Oedema
AggressionComa NecGeneral Physical Health DeteriorationHypertensionRespiratory Disorder NosTorsade De Pointes
Suicidal IdeationLoss Of Consciousness NecPruritusSomnolenceUrticaria NosRigors
StressCardiac DisorderPainUpper Respiratory Tract InfectionRed EyeVentricular Tachycardia
TearfulnessCerebrovascular AccidentInjuryInsomniaEye PainCardiac Failure Congestive
Abnormal BehaviourComplicated MigraineDeep Vein ThrombosisActivities Of Daily Living ImpairedHeadache NosFatigue
Suicide AttemptPain In ExtremityAdverse Drug ReactionDyspnoeaAtrial Fibrillation
General Physical Health DeteriorationUrticariaBlood Creatinine IncreasedAcute Respiratory FailureOedema Lower Limb

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of NyQuil and Benadryl on

Do you take NyQuil and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take NyQuil and Benadryl
- support group for people who take Benadryl
- support group for people who take NyQuil

Can you answer these questions (Ask a question):

More questions for: Benadryl, NyQuil

You may be interested at these reviews (Write a review):

  • Sids/benedryl infant stopped breathing
    We are devastated. Our grand daughter was being breastfed and mother only took 1 tablet of Benedryl 25 mg and healthy baby girl died of SIDS following morning. Any information is appreciated.
  • Diphenhydramine and mental acuity
    For at least 10 years, I have taken diphenhydramine 50 mg. at bedtime for insomnia and allergies. The results have been that I sleep well with no hangover or any cognitive impairment. If I experience vertigo from allergies, I may take an additional 50 mg. but never exceeding 100 mg in a 24 hour period.

    After reading the report regarding an Alzheimer's study finding that after taking as little as 4mg diphenhydramine daily for more than 3 years, dementia rates were high.

    I stopped the diphenhydramine one night. I experienced symptoms of deep brain pulsating pain and severe insomnia. After 4 hours, I took 50 mg diphenhydramine and slept very well. The next night I took 37.5 mg. diphenhydramine, slept very well. However, some of my tasks require layers of mental challenges in which I became slower.

    My question is how did the study recipients obtain 4 mg doses of diphenhydramine when the standard over-the-counter (OTC) availability in tablets is 25 mg? How reliable is the information submitted from the study subjects? What manufacturer's diphendramine was used, or were there several?

    I felt sharper mentally when on 50 mg daily than so far on 37.5 mg.
  • Constipation due to nyquil
    Very bad constipation. Had lower stomach pains for days
  • Thank god for my dog
    On May 1st I came home from work and had taken some Nyquil before bed. While I was sleeping(for 17hours) I had a massive stroke, which my dog sensed and saved my life by waking me up in time to call for help. I was life flighted to a different Hospital, I'm very honored to have such a wonderful pup!
  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.

More reviews for: Benadryl, NyQuil

Complete drug side effects:

On eHealthMe, Nyquil (acetaminophen; dextromethorphan; doxylamine; pseudoephedrine) is often used to treat cough. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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