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Review: Omeprazole and Metformin

This review analyzes the effectiveness and drug interactions between Omeprazole and Metformin. It is created by eHealthMe based on reports of 8,847 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Omeprazole and Metformin >>>

What are the drugs

Omeprazole (what 92,657 Omeprazole users reported?) has active ingredients of omeprazole. It is used in gastroesophageal reflux disease.

Metformin (what 100,768 Metformin users reported?) has active ingredients of metformin hydrochloride. It is used in diabetes.

On Sep, 12, 2014: 8,847 people who take Omeprazole, Metformin are studied

Omeprazole, Metformin outcomes

Drug combinations in study:
- Omeprazole (omeprazole)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Omeprazole is effective25.00%
(2 of 8 people)
54.17%
(13 of 24 people)
45.00%
(9 of 20 people)
70.97%
(22 of 31 people)
66.13%
(41 of 62 people)
77.59%
(45 of 58 people)
79.17%
(19 of 24 people)
0.00%
(0 of 1 people)
Metformin is effective30.77%
(4 of 13 people)
22.22%
(4 of 18 people)
39.13%
(9 of 23 people)
39.02%
(16 of 41 people)
44.07%
(26 of 59 people)
46.51%
(20 of 43 people)
51.85%
(14 of 27 people)
66.67%
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure AcuteNauseaRenal Failure AcuteErectile DysfunctionDiarrhoeaDiarrhoeaHyperkalaemiaNausea
Stevens-johnson SyndromeIdiopathic Thrombocytopenic PurpuraCardiac Failure CongestiveCholelithiasisHypocalcaemiaMetabolic AcidosisRenal Tubular AcidosisDyspnoea
Upper Gastrointestinal HaemorrhageRenal FailureArteriosclerosis Coronary ArteryDeep Vein ThrombosisTetanyHypomagnesaemiaGastric HaemorrhageDiarrhoea
CholangitisVomitingMyocardial InfarctionNauseaRenal Failure AcuteTetanyEncephalopathyPain
Malignant Neoplasm ProgressionUpper Gastrointestinal HaemorrhageBlood Creatinine IncreasedPainMyocardial InfarctionRenal Failure AcuteAnaemiaVomiting
General Physical Health DeteriorationHaemoglobin DecreasedPancreatitis NosVomitingAnxietyHypocalcaemiaHigh Blood SugarFatigue
AnuriaWeight DecreasedPainAbdominal PainGastric HaemorrhageLactic AcidosisLactic AcidosisBlood Glucose Increased
Cardiac ArrestRespiratory DistressDiarrhoeaDyspnoeaLactic AcidosisBack PainGastrointestinal PerforationChest Pain
DiarrhoeaDiabetes MellitusMalignant AscitesFatigueHypomagnesaemiaConstipationRenal Failure AcuteWeight Decreased
Lactic AcidosisPruritusFatigueOedema PeripheralAnaemiaMalaiseMulti-organ FailureRenal Failure Acute

Drug effectiveness by gender :

FemaleMale
Omeprazole is effective65.57%
(80 of 122 people)
67.62%
(71 of 105 people)
Metformin is effective41.67%
(50 of 120 people)
42.06%
(45 of 107 people)

Most common drug interactions by gender * :

FemaleMale
NauseaNausea
DyspnoeaDyspnoea
PainDiarrhoea
DiarrhoeaMyocardial Infarction
VomitingRenal Failure Acute
HeadacheBlood Glucose Increased
FatigueChest Pain
Weight DecreasedPain
Blood Glucose IncreasedFatigue
Chest PainAsthenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Omeprazole is effectiven/an/an/a66.67%
(2 of 3 people)
41.03%
(16 of 39 people)
40.91%
(27 of 66 people)
36.13%
(43 of 119 people)
43.15%
(63 of 146 people)
Metformin is effectiven/an/an/a25.00%
(1 of 4 people)
12.12%
(4 of 33 people)
26.15%
(17 of 65 people)
24.19%
(30 of 124 people)
27.74%
(43 of 155 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
OsteoporosisMuscle SpasmsAbdominal PainCholecystitis ChronicAgitationNauseaNauseaNausea
HyperlipidaemiaLactic AcidosisCholecystitis ChronicCholelithiasisWhite Blood Cell Count IncreasedDiabetes MellitusPainDyspnoea
HypercalcaemiaHeadache NosBiliary DyskinesiaAbdominal DistensionNeutrophil Count IncreasedChest PainDepressionDiarrhoea
HaematocheziaAbdominal Pain NosGallbladder DisorderPainComa Scale AbnormalPainAnxietyAsthenia
PalpitationsWeight IncreasedDiabetes Mellitus Inadequate ControlOverdoseDiarrhoeaBlood Glucose IncreasedRenal Failure Acute
Rash GeneralisedPainDiabetes MellitusDiabetes MellitusMyocardial InfarctionFatigueVomiting
HypoglycaemiaVomitingDiarrhoeaType 2 Diabetes MellitusHeadacheDiarrhoeaDizziness
Foetal Exposure During PregnancyInjuryNauseaNauseaAnxietyDyspnoeaWeight Decreased
Type 2 Diabetes MellitusNauseaAbdominal Pain UpperPainDyspnoeaBack PainPain
Transient Ischaemic AttackGastric DisorderAbdominal PainDiabetic NeuropathyDepressionChest PainBlood Glucose Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Omeprazole and Metformin
- group for people who take Metformin
- group for people who take Omeprazole

Comments from related studies:

  • From this study (3 weeks ago):

  • Naprosyn, Vicodin, Ativan and Prilosec are taken only on an as needed basis. Some of my symptoms are intermittent, and some are chronic. The though the medications may not completely rid me of a symptom (for example, depression or muscle pain), they do improve my condition enough to warrant their continued use. I'm much better off taking them than not.

    The oral issues I'm having all began around the same time in the last year. I first noticed a sensitivity for spicy food I had never experienced. I can no longer use adult toothpaste because the minty flavors are so provinces as to cause pain. The gum irritation comes and goes as does the severity of the other oral pain I experience.

    My hair loss I can describe as severe as it can be without having visible bald spots. Whereas I once had unusually thick hair (a ponytail of around 1.5 inches), I have lost so much that my ponytail now measures about .5 inches.

    Reply

  • From this study (1 month ago):

  • I don't know the possible relationship between daytime sleepiness (comes in spurts or cycles) and Metformin. (or Metformin + Paroxetine)

    Reply

  • From this study (3 months ago):

  • Vertigo, nausea and deafness seem to come and go. I also get fulness in the ear. With no seemingly causing factor. Was told I had meniers disease. However have now been told I may have auditory neuropathy.

    Reply

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    I had a heart attack 3yrs ago, finding it hard to handle. Waiting for a complete knee replacement, also long history of back problems. Chronic pain. Diabetic on insulin.

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More questions for: Metformin, Omeprazole

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    I've found that the metformin does not smell especially bad, but when I first started taking it, I could smell something horrible - to the point where I pulled apart my cupboards and fridge, fully expecting to find some maggot-riddled rotting meat. Eventually I realized I was smelling normal smel ...

More reviews for: Metformin, Omeprazole

Complete drug side effects:

On eHealthMe, Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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