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Related topic: Metformin, Omeprazole

Review: Omeprazole and Metformin

This review analyzes the effectiveness and drug interactions between Omeprazole and Metformin. It is created by eHealthMe based on 8,833 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 10, 2014: 8,833 people who take Omeprazole, Metformin are studied

Omeprazole, Metformin outcomes

Drug combinations in study:
- Omeprazole (omeprazole)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Omeprazole is effective28.57%
(2 of 7 people)
56.52%
(13 of 23 people)
42.11%
(8 of 19 people)
73.33%
(22 of 30 people)
65.52%
(38 of 58 people)
76.79%
(43 of 56 people)
77.27%
(17 of 22 people)
0.00%
(0 of 1 people)
Metformin is effective27.27%
(3 of 11 people)
22.22%
(4 of 18 people)
39.13%
(9 of 23 people)
41.03%
(16 of 39 people)
43.86%
(25 of 57 people)
47.50%
(19 of 40 people)
50.00%
(12 of 24 people)
50.00%
(1 of 2 people)

Drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure Acute
(13 reports)

Stevens-johnson Syndrome
(12 reports)

Upper Gastrointestinal Haemorrhage
(11 reports)

Cholangitis
(10 reports)

Malignant Neoplasm Progression
(9 reports)

Nausea
(9 reports)

Idiopathic Thrombocytopenic Purpura
(8 reports)

Renal Failure
(6 reports)

Vomiting
(6 reports)

Respiratory Distress
(5 reports)

Renal Failure Acute
(6 reports)

Cardiac Failure Congestive
(3 reports)

Arteriosclerosis Coronary Artery
(3 reports)

Myocardial Infarction
(3 reports)

Blood Creatinine Increased
(3 reports)

Erectile Dysfunction
(11 reports)

Cholelithiasis
(6 reports)

Deep Vein Thrombosis
(5 reports)

Nausea
(5 reports)

Pain
(5 reports)

Diarrhoea
(13 reports)

Hypocalcaemia
(12 reports)

Tetany
(11 reports)

Renal Failure Acute
(10 reports)

Myocardial Infarction
(9 reports)

Diarrhoea
(22 reports)

Metabolic Acidosis
(12 reports)

Hypomagnesaemia
(11 reports)

Tetany
(11 reports)

Renal Failure Acute
(10 reports)

Hyperkalaemia
(25 reports)

Renal Tubular Acidosis
(25 reports)

Gastric Haemorrhage
(8 reports)

Encephalopathy
(7 reports)

High Blood Sugar
(5 reports)

Nausea
(533 reports)

Dyspnoea
(513 reports)

Pain
(509 reports)

Diarrhoea
(456 reports)

Vomiting
(381 reports)

Drug effectiveness by gender :

FemaleMale
Omeprazole is effective65.52%
(76 of 116 people)
67.68%
(67 of 99 people)
Metformin is effective41.59%
(47 of 113 people)
41.58%
(42 of 101 people)

Drug interactions by gender * :

FemaleMale
Common drug interactions Nausea
(555 reports)

Dyspnoea
(392 reports)

Pain
(369 reports)

Diarrhoea
(368 reports)

Vomiting
(358 reports)

Nausea
(273 reports)

Dyspnoea
(249 reports)

Diarrhoea
(223 reports)

Myocardial Infarction
(216 reports)

Renal Failure Acute
(212 reports)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Omeprazole is effectiven/an/an/a66.67%
(2 of 3 people)
40.00%
(14 of 35 people)
53.33%
(24 of 45 people)
37.07%
(43 of 116 people)
43.80%
(60 of 137 people)
Metformin is effectiven/an/an/a25.00%
(1 of 4 people)
13.79%
(4 of 29 people)
36.36%
(16 of 44 people)
23.97%
(29 of 121 people)
26.90%
(39 of 145 people)

Drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Common drug interactions Osteoporosis
(2 reports)

Hyperlipidaemia
(2 reports)

Hypercalcaemia
(2 reports)

Haematochezia
(2 reports)

Palpitations
(2 reports)

Muscle Spasms
(1 report)

Lactic Acidosis
(1 report)

Abdominal Pain
(9 reports)

Cholecystitis Chronic
(9 reports)

Biliary Dyskinesia
(8 reports)

Gallbladder Disorder
(8 reports)

Weight Increased
(6 reports)

Cholecystitis Chronic
(9 reports)

Cholelithiasis
(9 reports)

Abdominal Distension
(7 reports)

Pain
(6 reports)

Diabetes Mellitus Inadequate Control
(6 reports)

Agitation
(95 reports)

White Blood Cell Count Increased
(86 reports)

Coma Scale Abnormal
(85 reports)

Neutrophil Count Increased
(85 reports)

Overdose
(83 reports)

Nausea
(91 reports)

Diabetes Mellitus
(83 reports)

Chest Pain
(67 reports)

Pain
(63 reports)

Diarrhoea
(61 reports)

Nausea
(201 reports)

Pain
(151 reports)

Depression
(138 reports)

Anxiety
(137 reports)

Blood Glucose Increased
(127 reports)

Nausea
(370 reports)

Dyspnoea
(327 reports)

Diarrhoea
(317 reports)

Asthenia
(287 reports)

Renal Failure Acute
(285 reports)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

  • From this study (2 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (2 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

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