Review: Omeprazole and Metformin drug interactions
This review analyzes the interactions between Omeprazole and Metformin. It is created by eHealthMe based on 8,343 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Omeprazole (latest outcomes from 92,355 users) has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease.
Metformin (latest outcomes from 100,457 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.
On Feb, 27, 2014: 8,343 people who reported to have interactions when taking Omeprazole, Metformin are studied
Drug combinations in study:
- Omeprazole (omeprazole)
- Metformin (metformin hydrochloride)
Most common interactions experienced by people in the use of Omeprazole, Metformin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Dyspnoea (difficult or laboured respiration)||1,359|
|Nausea (feeling of having an urge to vomit)||837|
|Fatigue (feeling of tiredness)||553|
|Blood Glucose Increased||477|
|Renal Failure Acute (rapid kidney dysfunction)||429|
Most common interactions experienced by people in long term use of Omeprazole, Metformin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Hyperkalaemia (damage to or disease of the kidney)||63|
|Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)||34|
|Renal Tubular Acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)||25|
|Renal Failure Acute (rapid kidney dysfunction)||24|
|Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)||23|
|Tetany (involuntary contraction of muscles)||22|
|Hypocalcaemia (levels of calcium in blood serum are abnormally low)||21|
|Lactic Acidosis (low ph in body tissues)||18|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Diabetes mellitus
- Type 2 diabetes mellitus
- Gastrooesophageal reflux disease
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Omeprazole is used in:
- Metformin is used in:
Other drugs that are used to treat the same conditions:
- Omeprazole alternatives:
- Metformin alternatives:
Comments from related studies:
From this study (3 days ago):
From this study (3 days ago):
From this study (1 week ago):
Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.
Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.
it seems that I've become more down and depressed while on the lamictal. I took 50 mg. for 2 weeks and am now in the midst of taking 100 mg. I taken that for about 10 days now.
Can you answer these questions (what is this?):
- By Annie: I am taking omeprazole and ranitidine for acid reflux both seem to be giving me side effects fatigue, dizziness
I took esomoprazole ( nexium ) 20 mg for acid reflux for thirteen days but felt so unwell side effects fatigue and feeling very unsteady and disoriented , not all the time but enough to make me want to stop taking it. It had however diminished my cough and sore throat caused by the reflux. My gastro ...
- By Herb: Can xarelto cause my blood pressure to elevate
I had a stroke (TIA) TWO MONTHS AGO AND MY DOCTOR PUT ME ON A BLOOD THINNER XARELTO and my blood pressure is always high now. Example 197/112
- By pegleg: Can benicar cause neurophy
burning pain in arms, hands, legs, and feet..Gets worse at night
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- By novzchan: Tonsillitis for 1 week
i suffered tonsillitisfor a week. and i lose my weight coz i kept on vomiting. we rushed into my doctor's clinic. he advised me to stay in the hospital for 3 days cause my tonsillitis was really severe. he prescribed me cefuroxime axetil via IV for further absorption and omeprazole via IV for my sto ...
Recent related drug studies:
- A study of drug interactions between Vitamin D, Tramadol, Multivitamin, Ropinirole Hydrochloride, Omeprazole, Nitroglycerin, Methocarbamol, Metformin Hydrochloride, Lisinopril, Gabapentin, Cymbalta, Dicyclomine Hydrochloride, Calcium Carbonate, Atorvastatin Calcium, Aspirin, Amlodipine for a patient with Vitamin D Deficiency, Drugs For Pain, Daily Vitamin Tablet, Restless Leg Syndrome, Gerd, Chest Pain, Back Muscke Spasm, Diabetes Mellitus Non Insulin-dependent, High Balm, Meralgia Paraesthetica, Ibs, Ankle Replacement, High Blood Cholesterol, Prophylaxis. The patient has Restless Leg Syndrome, Chrinically Elevated Wbcs - 10.5 - 13.0
- A study of drug interactions between Lamictal, Saphris, Omeprazole, METFORMIN, GLIPIZIDE, HCTZ, Crestor, Lisinopril, Xanax, Prozac for a patient with Depression, Bipolar, Gastritis, Diabetes, Blood Pressure, Lower Cholesterol, Sleepy. The patient has Depressive Symptom
- A study of drug interactions between Soluble Fiber, Melatonin, Naproxen, Aspirin, Calcium, Vitamin D, Lyrica, Micardis Hct, Crestor, Glyburide, Metformin, Omeprazole for a patient with Constipation, Sleep Disorder Due To General Medical Condition, Insomnia Type, Arthritis - Osteoarthritis, Cardiovascular Disorder, Secondary Hyperparathyroidism, Diabetic Neuropathy, High Blood Pressure, High Blood Cholesterol And Triglycerides, Type 2 Diabetes Mellitus, Stomach Pain. The patient has Muscle Cramps, Chest Pain, Edema - Peripheral, Peripheral Edema (Foot, leg, and ankle swelling)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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