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Review: Omeprazole and Metformin





Summary: drug interactions are reported among people who take Omeprazole and Metformin together.

This review analyzes the effectiveness and drug interactions between Omeprazole and Metformin. It is created by eHealthMe based on reports of 8,857 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Omeprazole and Metformin >>>

What are the drugs

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. (latest outcomes from Omeprazole 92,773 users)

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (view latest outcomes from 100,893 users)

On Dec, 15, 2014: 8,857 people who take Omeprazole, Metformin are studied

Omeprazole, Metformin outcomes

Drug combinations in study:
- Omeprazole (omeprazole)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Omeprazole is effective25.00%
(2 of 8 people)
54.17%
(13 of 24 people)
47.62%
(10 of 21 people)
72.73%
(24 of 33 people)
65.15%
(43 of 66 people)
77.59%
(45 of 58 people)
81.48%
(22 of 27 people)
0.00%
(0 of 1 people)
Metformin is effective30.77%
(4 of 13 people)
26.32%
(5 of 19 people)
39.13%
(9 of 23 people)
37.78%
(17 of 45 people)
45.16%
(28 of 62 people)
45.45%
(20 of 44 people)
50.00%
(14 of 28 people)
66.67%
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure AcuteNauseaRenal Failure AcuteErectile DysfunctionDiarrhoeaDiarrhoeaRenal Tubular AcidosisNausea
Stevens-johnson SyndromeIdiopathic Thrombocytopenic PurpuraCardiac Failure CongestiveCholelithiasisHypocalcaemiaMetabolic AcidosisHyperkalaemiaDyspnoea
Upper Gastrointestinal HaemorrhageVomitingArteriosclerosis Coronary ArteryNauseaTetanyHypomagnesaemiaGastric HaemorrhageDiarrhoea
CholangitisRenal FailureMyocardial InfarctionDeep Vein ThrombosisRenal Failure AcuteTetanyEncephalopathyPain
Malignant Neoplasm ProgressionHaemoglobin DecreasedBlood Creatinine IncreasedPainAnxietyRenal Failure AcuteHigh Blood SugarVomiting
General Physical Health DeteriorationPruritusPainAbdominal PainMyocardial InfarctionHypocalcaemiaAnaemiaFatigue
AnuriaFatigueDiarrhoeaVomitingLactic AcidosisLactic AcidosisGastrointestinal PerforationBlood Glucose Increased
Cardiac ArrestRespiratory DistressPancreatitis NosDyspnoeaGastric HaemorrhageBack PainMulti-organ FailureChest Pain
DiarrhoeaDiabetes MellitusMalignant AscitesWeight GainHypomagnesaemiaConstipationLactic AcidosisWeight Decreased
Lactic AcidosisUpper Gastrointestinal HaemorrhageFatigueOedema PeripheralPulmonary FibrosisMalaiseRenal Failure AcuteRenal Failure Acute

Drug effectiveness by gender :

FemaleMale
Omeprazole is effective66.41%
(85 of 128 people)
67.89%
(74 of 109 people)
Metformin is effective40.48%
(51 of 126 people)
43.24%
(48 of 111 people)

Most common drug interactions by gender * :

FemaleMale
NauseaNausea
DyspnoeaDyspnoea
PainDiarrhoea
DiarrhoeaMyocardial Infarction
VomitingRenal Failure Acute
HeadacheBlood Glucose Increased
FatigueChest Pain
Weight DecreasedPain
Blood Glucose IncreasedFatigue
Chest PainAsthenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Omeprazole is effectiven/an/an/a66.67%
(2 of 3 people)
41.03%
(16 of 39 people)
32.32%
(32 of 99 people)
36.29%
(45 of 124 people)
43.54%
(64 of 147 people)
Metformin is effectiven/an/an/a25.00%
(1 of 4 people)
12.12%
(4 of 33 people)
20.41%
(20 of 98 people)
24.03%
(31 of 129 people)
27.56%
(43 of 156 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
OsteoporosisMuscle SpasmsAbdominal PainCholecystitis ChronicAgitationNauseaNauseaNausea
HyperlipidaemiaLactic AcidosisCholecystitis ChronicCholelithiasisWhite Blood Cell Count IncreasedDiabetes MellitusPainDyspnoea
HypercalcaemiaHeadache NosBiliary DyskinesiaAbdominal DistensionNeutrophil Count IncreasedChest PainDepressionDiarrhoea
HaematocheziaAbdominal Pain NosGallbladder DisorderPainComa Scale AbnormalPainAnxietyAsthenia
PalpitationsWeight IncreasedDiabetes Mellitus Inadequate ControlOverdoseDiarrhoeaBlood Glucose IncreasedRenal Failure Acute
Rash GeneralisedPainDiabetes MellitusDiabetes MellitusMyocardial InfarctionFatigueVomiting
HypoglycaemiaVomitingDiarrhoeaType 2 Diabetes MellitusHeadacheDiarrhoeaDizziness
Foetal Exposure During PregnancyInjuryNauseaNauseaAnxietyDyspnoeaWeight Decreased
Type 2 Diabetes MellitusNauseaAbdominal Pain UpperPainDyspnoeaChest PainPain
Transient Ischaemic AttackGastric DisorderAbdominal PainDiabetic NeuropathyDepressionBack PainBlood Glucose Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Omeprazole and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Omeprazole and Metformin
- support group for people who take Metformin
- support group for people who take Omeprazole

Can you answer these questions (Ask a question):

More questions for: Metformin, Omeprazole

You may be interested at these reviews (Write a review):

  • Irregular heatbeat and prilosec
    I am 65 M and a long history of Moderate hypertension. I am overweight, out of shape. 15-20 years ago when I didn't take BP medicine I had occasional PVCs, heart skips a beat.

    Since I have been on Metoprolol (beta blocker) and Cozaar my BP is normal and heartbeat normal.
    I have been on that regimen 15-20 years.

    Now or in the last weeks or 2 I notice skipped beats and irregular, fast to slow and back on occasion

    Recently It was suggested I may have sleep apnea and was definitely diagnosed with bad acid reflux by an Ear nose and throat specialist.

    I was told to go on 2 OTC Prevacid/day for 3 months. I instead, since I had them, went on Prilosec-- slightly different.

    I have been on Prilosec 2 or so weeks maybe 3.
    It clicked in my mind today that maybe there is a connection.

    I have a pretty expensive pulse oximeter (electronic finger thingy) and I can actually see flat lines and skipped beats and strength of pulse. Oxygen is 90 to 94. Also I started taking aspirin out of fear

    Anyone else?
  • Hair loss with metformin hydrochloride usage
    I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this drug should post that this is a side effect as so many have been complaining of the same side effect. I also began having problems with my teeth and always prided myself of having great teeth with no problems. I also understand that if there is a deficiency of Vitamin B12 that this together with taking this drug can cause these issues of hair loss and mouth/teeth problems. Again; I feel this should be totally and more readily informed to anyone taking this drug. I don't feel that anyone should have to give up things important to them to maintain a healthy way of living...I am going to see my physician and discuss what other options that may exist as I am not feeling very comfortable with this drug and the side effects I am experiencing.
  • Ranexa and erectile dysfunction
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
  • Victoza and liver cancer (cholangiocarcinoma)
    My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreatic cancer are similar, is there a link between Victoza and cholangiocarcinoma?
  • Prednisone mixed results-it lets me breath
    have been on prednisone now for 3 years straight. Am taking 30mg a day just to breath. every time i have tried to taper off i have ended up in the emergency room unable to breath. That has been 7 times in the last year. I am 49 years old and was in good health 3-4 years ago. got a cough and it has been down hill.Prednisone worked great at first but then it starts to destroy the body.Had nasal passage surgery(waste of time)have broken many ribs from coughing.painful.when you are on prednisone your body takes 3-5 times longer to heal.craked tailbone from a slip. have seen over 12 doctors.reasonable gueswork. My best doc which is mine says do you want to suffocate to death or let your body try and fix itself if it can. im not for suffocation at all. Just a good medicine to counter the angriness of the steroid. Any ideas i am all ears. oh ya my eyes are starting to go and my joints as well

More reviews for: Metformin, Omeprazole

Comments from related studies:

  • From this study (1 month ago):

  • Diarrhea occurs a day and a half after taking omeprazole. This only started after starting metformin.

    Reply

  • From this study (2 months ago):

  • I had some hair thinning over the past 10+ years and was told it was due to HBP and medications. Since taking phentermine and topiramate for weight loss along with the other meds hair loss has tripled at a radical rate. I stopped taking topiramate about a month ago and still the hair keeps falling out. When will it stop and will my hair grow back. The doctor recommended 5% minoxidil along with the vitamins I'm taking. I've been taking 10,000 mcg. Biotin, Hair Skin & Nails, E and Fish oil (used to help reduce the cholesterol).

    Reply

  • From this study (2 months ago):

  • Naprosyn, Vicodin, Ativan and Prilosec are taken only on an as needed basis. Some of my symptoms are intermittent, and some are chronic. The though the medications may not completely rid me of a symptom (for example, depression or muscle pain), they do improve my condition enough to warrant their continued use. I'm much better off taking them than not.

    The oral issues I'm having all began around the same time in the last year. I first noticed a sensitivity for spicy food I had never experienced. I can no longer use adult toothpaste because the minty flavors are so provinces as to cause pain. The gum irritation comes and goes as does the severity of the other oral pain I experience.

    My hair loss I can describe as severe as it can be without having visible bald spots. Whereas I once had unusually thick hair (a ponytail of around 1.5 inches), I have lost so much that my ponytail now measures about .5 inches.

    Reply

    Sumac on Oct, 24, 2014:

    I think a lot of you have disseminated histoplasmosis. Histoplasmosis is carried by bats.

    Reply

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Complete drug side effects:

On eHealthMe, Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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