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Review: Oxycodone 5/apap 500 and Depakote





Summary: drug interactions are reported among people who take Oxycodone 5/apap 500 and Depakote together.

This review analyzes the effectiveness and drug interactions between Oxycodone 5/apap 500 and Depakote. It is created by eHealthMe based on reports of 503 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Oxycodone 5/apap 500 and Depakote >>>

What are the drugs

Oxycodone 5/apap 500 has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycodone 5/apap 500 277 users)

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 30,928 users)

On Nov, 25, 2014: 503 people who take Oxycodone 5/apap 500, Depakote are studied

Oxycodone 5/apap 500, Depakote outcomes

Drug combinations in study:
- Oxycodone 5/apap 500 (acetaminophen; oxycodone hydrochloride)
- Depakote (divalproex sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Oxycodone 5/apap 500 is effective62.50%
(5 of 8 people)
20.00%
(1 of 5 people)
n/a100.00%
(2 of 2 people)
25.00%
(1 of 4 people)
n/an/an/a
Depakote is effective50.00%
(3 of 6 people)
0.00%
(0 of 3 people)
50.00%
(1 of 2 people)
n/a25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
100.00%
(2 of 2 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RhabdomyolysisMental Status ChangesType 2 Diabetes MellitusType 2 Diabetes MellitusVomitingItchingWeight IncreasedPain
Scrotal SwellingSuicidal IdeationObesityHyperglycaemic Hyperosmolar Nonketotic SyndromeBiliary DyskinesiaNumbness In Hands Or FeetNausea
AnaemiaWeight IncreasedBlood Triglycerides IncreasedNeurogenic BladderNauseaAnxiety
AggressionContusionBlood Cholesterol IncreasedCerebrovascular AccidentCholecystitis ChronicHeadache
Anal InjuryUrinary Tract InfectionAgitated DepressionAbdominal Pain UpperDepression
Renal ImpairmentIncreased AppetiteAnxiety AggravatedPyrexiaType 2 Diabetes Mellitus
PyrexiaGastric UlcerDepressionArthralgia
FatigueHepatic SteatosisSuicidal IdeationDiabetes Mellitus
Stomach DiscomfortEpistaxisBlood Glucose IncreasedDyspnoea
Haematocrit DecreasedInternational Normalised Ratio IncreasedMood SwingsChest Pain

Drug effectiveness by gender :

FemaleMale
Oxycodone 5/apap 500 is effective63.64%
(7 of 11 people)
25.00%
(2 of 8 people)
Depakote is effective40.00%
(4 of 10 people)
44.44%
(4 of 9 people)

Most common drug interactions by gender * :

FemaleMale
PainDiabetes Mellitus
NauseaType 2 Diabetes Mellitus
AnxietyNausea
DepressionFall
HeadacheChest Pain
ArthralgiaDyspnoea
MigraineHeadache
Pain In ExtremityAnxiety
InsomniaDizziness
Type 2 Diabetes MellitusConvulsion

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Oxycodone 5/apap 500 is effectiven/an/a100.00%
(1 of 1 people)
50.00%
(3 of 6 people)
28.57%
(2 of 7 people)
66.67%
(2 of 3 people)
25.00%
(1 of 4 people)
0.00%
(0 of 3 people)
Depakote is effectiven/an/a0.00%
(0 of 1 people)
28.57%
(2 of 7 people)
83.33%
(5 of 6 people)
33.33%
(1 of 3 people)
0.00%
(0 of 4 people)
0.00%
(0 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Heart Rate Decreasedn/aObesityVomitingNauseaType 2 Diabetes MellitusPainFall
NasopharyngitisHyperglycaemiaType 2 Diabetes MellitusPainNeuropathy PeripheralAnxietyDyspnoea
HeadacheDepressionCholecystitis ChronicDrug DependenceArthralgiaConfusional StateHeadache
Brain DamageType 1 Diabetes MellitusOverdoseDepressionHeadacheBack PainChest Pain
AmnesiaDiabetic KetoacidosisAbdominal Pain UpperAnxietyDiabetes MellitusNauseaAnxiety
Balance DisorderGlycosuriaCholelithiasisBipolar I DisorderDepressionFatigueAsthenia
AbasiaWeight IncreasedPancreatitisAsthmaPain In ExtremityDiarrhoeaConfusional State
NauseaNauseaArthralgiaInsomniaDepressionMyocardial Infarction
Biliary ColicDiabetic NeuropathyBronchitisPainChest DiscomfortNausea
Abdominal DistensionAbdominal PainDysuriaAbdominal PainArthralgiaLoss Of Consciousness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Oxycodone 5/apap 500 and Depakote?

You are not alone! Join a related mobile support group:
- support group for people who take Oxycodone 5/apap 500 and Depakote
- support group for people who take Depakote
- support group for people who take Oxycodone 5/apap 500

Can you answer these questions (Ask a question):

More questions for: Depakote, Oxycodone 5/apap 500

You may be interested at these reviews (Write a review):

  • Percocet and memory loss
    A close friend of mine has been using prescription Percocet for 5 to 6 years. Her MD first prescribed the lowest dosage possible to be taken 3 to 4 times daily for pain. I am aware that this medication frequently needs to be increased because it will become less effective. I don't know how many times he has increased the dosage but it has been many times. I believe now she is taking the highest dosage of it up to four to six times daily and six tablets at a time. I have made several attempts to tell her the information I know about Percocet and to have her to ask her MD about her now short and long term memory problems. Her response is to shout at me, telling me she needs that much for pain and to mind my own business when I tell her about the negative side effects I see, especially her daily and hourly memory problems. She has also said she has no reason to speak to her doctor about memory problems. I think that is because she fears he might lower the dosage. My concern about her poor memory only causes her to tell me I am the one with a bad memory, even though the only pain meds I infrequently take are OTC ones. According to my MD, I have been told my memory for my age of 63 is perfectly fine and better than most for my age. Also I take no medications with the side effects that cause memory problems. In addition when my MD prescribes new medication I always read the info that accompanies them, do research online and pay attention to all warnings and side effect info. The few times I have had side effects they have only been GI problems and I have consulted my MD regarding those and work with my MD for an alternative medication. My friend NEVER EVER reads any of the accompanying material that comes with her prescriptions. Also she never looks up her medications online to get additional information, including possible side effects. I worry about her very much and fear she now has an addiction to Percocet. Several years ago she asked her MD for Chantix to stop smoking, never reading the info supplied with the prescription. I urged to read the info and side effects. She declined, telling me she knew what she was doing. After two weeks of using Chantix she had a mental break down and ended up on the psych ward of our local hospital for 3 weeks. That medication was the first that began to cause her to have memory problems. She accepted that fact for about a month then dismissed it claiming her memory problems were over. They weren't because she was still taking Percocet. I understand no one wants to be told by a friend they suspect that person has memory problems, but I haven't done so to be mean or cruel, but only out of great love and concern. At this point with all the Percocet she takes daily she really is at a level to be considered an addict and I fear soon she will convince her MD to increase the dosage because it no longer controls her pain. I've written this review as a cautionary tale to inform others to be vigilant with their family, friends and loved ones as Percocet can and does cause short and long term memory loss. Although all my efforts to assist and speak to my friend have failed, please don't give up on those in your life who you notice are experiencing memory loss signs that take Percocet. If possible speak to them or their MD. Oh, and be prepared to be yelled at that you are the one with memory problems or to be told to mind your own business. And please, please read the information that accompanies all of your medications.
  • Seizure patient was on depakote for 16 years now on keppra 1500 mg.
    I am 28 years old and been off depakote for 5 months. I started keppra to control my seizure disorder, which works great. But for the past year I have developed osteoarthritis in my thoracic, si joints, and lumbar. I get alot of muscle hypersensitivity and pain. Can any of this be due to long term effects of seizure meds?
  • Why does my urine smell bad?
    urine has very strong fowel odor. smells like rotting meat. very concentrated and cloudy and dark color.
  • Which issue has caused my periodontitis, my fibromyalgia or spinal stenosis? (2 responses)
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    Also since 2010, I was diagnosed with Periodontitis and have been losing all of My teeth in the top of My mouth.
    I am 44 yrs old now, have been on disability for the last 4 years. I am down to 6 teeth in the top of My mouth, since having 1 removed just last week. They are telling Me that 3 more need to come out, and I am trying not to sink into total depression, especially since these are now My front teeth. I have a appointment today for a Denture Exam.

    I started researching today to see if this Periodontitis is related to either My Spinal Stenosis or My Fibromyalgia. Especially since I once again looked up the definition for Periodontitis. Which States;

    **Periodontal Disease and Bone Health. Periodontitis is a chronic infection that affects the gums and the bones that support the teeth. Bacteria and the body's own immune system break down the bone and connective tissue that hold teeth in place.

    Of course with My disease of Spinal Stenosis and the bone loss as well as the nerve narrowing, I thought the breaking down of the bone in the gums might have a connection. Research didnt find any linking.

    Now with Fibromyalgia, research showed 6 out of 17 thousand that they found. LOL Wow.. Well I guess I am "Number 7". Lucky Me! But it does make more sense now that looking at the definition. It is a Chronic infection (which Fibromyalia does create these) that effects the gums and bones. Bacteria and The Body's own Immune System break down the bone and connective tissue that hold the teeth. Which with Fibromyalgia, our Immune System is always all kinds of "Crazy"!

    Oh course you can not have any of these diseases, or any other health issues and wind up with Periodontitis. It happens. But I know from lots of reading, researching and living with Fibromyalgia, that it is "Very Possible"!

    I would sure like to know what others with these 2 diseases are experiencing.
    Have a Blessed Day.
  • Eczema and birth control-microgestin
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More reviews for: Depakote, Oxycodone 5/apap 500

Comments from related studies:

  • From this study (2 years ago):

  • I was in a car accident in 2000. My lower back was trashed, and had to be reconstructed basically. I have fusions and titanium, all of this as causd many other health problems to arise over the last 10 years. But, I live a pretty normal life, most people don't even know there is anything wrong with me. : )

    Ultracet and Ultram, any drug from that family can be very dangerous, I had a serious reaction with Ultracet. I had 3 seizures before we figured out what was happening to me.

    Solu-Medrol was used in the hospital through my IV, for a complicated migraine problem. I do not know if I had some kind of allergic reaction to it, or if that drug just does that to people, but, I was ripping the IV out of my arm! I couldn't stand it! It felt like fire ants were under every inch of my skin crawling and biting me all the way down and back up my arms and legs! It took hours to stop, and it did not help the migraine either.

    Reply

    Allergic... on Mar, 6, 2013:

    allergic reaction to vancomycin and sulfamethoxazole....
    I was given vancomycin through an iv 2 days ago. Today I decided to take some sulfamethoxazole and the allergic reaction is unbearable. It's been 4 hrs and the burning aching hasn't stopped. How did u manage to stop the allergic reaction. I'm wondering if I should wait it out or go into er.

    Reply

  • From this study (2 years ago):

  • I was wondering if all of these together could have an adverse effect on my liver?

    Reply

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Complete drug side effects:

On eHealthMe, Oxycodone 5/apap 500 (acetaminophen; oxycodone hydrochloride) is often used to treat pain. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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