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Review: taking Oxycodone and Benadryl together

Summary: drug interactions are reported among people who take Oxycodone and Benadryl together.

This review analyzes the effectiveness and drug interactions between Oxycodone and Benadryl. It is created by eHealthMe based on reports of 1,817 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Oxycodone and Benadryl >>>

What are the drugs

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from 555 Oxycodone hydrochloride users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,395 Benadryl users)

On Feb, 25, 2015: 1,817 people who take Oxycodone Hydrochloride, Benadryl are studied

Oxycodone Hydrochloride, Benadryl outcomes

Drug combinations in study:
- Oxycodone Hydrochloride (oxycodone hydrochloride)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Oxycodone Hydrochloride is effective20.00%
(1 of 5 people)
100.00%
(2 of 2 people)
50.00%
(1 of 2 people)
100.00%
(3 of 3 people)
75.00%
(3 of 4 people)
100.00%
(3 of 3 people)
33.33%
(1 of 3 people)
n/a
Benadryl is effective20.00%
(1 of 5 people)
20.00%
(1 of 5 people)
n/an/a20.00%
(1 of 5 people)
60.00%
(3 of 5 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)

Drug effectiveness by gender :

FemaleMale
Oxycodone Hydrochloride is effective75.00%
(9 of 12 people)
44.44%
(4 of 9 people)
Benadryl is effective36.36%
(4 of 11 people)
30.00%
(3 of 10 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Oxycodone Hydrochloride is effectiven/an/an/a50.00%
(3 of 6 people)
15.38%
(4 of 26 people)
80.00%
(4 of 5 people)
7.14%
(2 of 28 people)
0.00%
(0 of 3 people)
Benadryl is effectiven/an/a0.00%
(0 of 1 people)
28.57%
(2 of 7 people)
9.09%
(2 of 22 people)
60.00%
(3 of 5 people)
0.00%
(0 of 28 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConstipationAnxietyAnxietyDrug DependenceDrug DependenceNauseaHot FlashesPain
Febrile NeutropeniaConstipationNauseaComaDepressionInsomniaSweating IncreasedAnxiety
NauseaPainMemory ImpairmentPyrexiaDrug Withdrawal SyndromeHyperhidrosisItchingNausea
DeathDepressionHeadacheNauseaInsomniaHeadacheDermatitis AcneiformBack Pain
PyrexiaDrug DependenceDrug Withdrawal SyndromeDepressionFallNervousnessPain ExacerbatedVomiting
MalaiseDrug Withdrawal SyndromeSomnolenceContusionConstipationOedema PeripheralLow Blood PressureArthralgia
HypersensitivityAtelectasisFallRespiratory FailureAstheniaWeight DecreasedAngerOsteonecrosis Of Jaw
RhinorrhoeaPneumoniaSedationHepatic SteatosisHeadacheTremorStressPyrexia
Renal FailureHaemangioma Of LiverComaHepatic FibrosisAnxietyPain In ExtremityDemerol OverdoseDyspnoea
PruritusPulmonary GranulomaPanic AttackCardiac ArrestNauseaDrug Withdrawal SyndromeFall

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyAnxiety
NauseaBack Pain
ArthralgiaNausea
Osteonecrosis Of JawVomiting
VomitingDepression
DiarrhoeaPneumonia
Back PainPyrexia
FallArthralgia
OsteoarthritisAsthenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aRespiratory ArrestVomitingAccidental OverdoseFatiguePainAnxietyNausea
Accidental Drug Intake By ChildPainMultiple Drug OverdosePainAnxietyPainVomiting
Cardiac ArrestPyrexiaCardiac ArrestDiarrhoeaBack PainNauseaPain
Drug ToxicityBlood Culture PositiveNauseaBack PainDepressionFallPneumonia
Bone PainStaphylococcal InfectionRespiratory ArrestPyrexiaAstheniaOsteoarthritisFall
AnorexiaGastrointestinal HaemorrhageVomitingArthralgiaNauseaOsteonecrosis Of JawOsteoarthritis
Diarrhoea NosParaesthesiaPainVomitingHeadachePyrexiaOsteonecrosis Of Jaw
DeathChillsDiarrhoeaDyspnoeaPain In ExtremityVomitingDiarrhoea
Viral Infection NosInfectionPulmonary EmbolismDepressionVomitingInjuryAnaemia
Abdominal Pain NosDevice Related InfectionCompleted SuicideAnxietyPain In JawInsomniaPyrexia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Oxycodone and Benadryl on

Do you take Oxycodone and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Oxycodone and Benadryl
- support group for people who take Benadryl
- support group for people who take Oxycodone Hydrochloride

Can you answer these questions (Ask a question):

  • I injected suboxone and now i feel weird this is not the first time i done it but the first time my arm is numb all over dizziness purple pinkish splotches all over my arm wat is wrong
    I shot an eighth of suboxone today and now my arm is purplish and red blotches there was no pain during or after injection only numbness dizziness and I can't get my nail nd to go to white it stays red this has never happened before.
  • What are safe alternatives to oxycontin? since moving to florida., no pharmacy stocks or can order it. suggestions?
    I've been on OxyContin for several years with pretty good results managing severe pain. Since moving south I'm finding that pharmacies cannot/will not carry it. Sent ex fr. Local md to mail order--one week later, still waiting.
    I'm desperate to find an effective alternative. Ideas?
  • I tested positive for methadone, i have never taken this drug (1 answer)
    I tested positive for methadone, I have never taken this drug. My Dr said I had to have taken it because it was there and that a false positive is out of the question. Could my meds cause methadone to show up on a urine drug test
  • I amwondering if i have myathesia gravis (1 answer)
    I am thinking that after a long bout of going nowhere with Drs. That I might have Myathesia Gravis. My Grandmother had it and I am thinking that my brother had it when he was born.He failed to thrive at first as he was unable to suck very well. He did make it though with a forced feeding of milk and bananas. He was sickly all his life though and recently died of cancer. I noticed that my eye is drooping on the left side. I have periods of extream fatigue, my left arm is tingly and I can't seem to feed myself without changing to my right hand. I have spinal stenosis and severe pain in my hip area but my right big toe seems to be tingly from time to time. I also have a swallow problem that causes me to choke or throw up the food or drink. Pills stay part way down a lot. My G.I. guy wants to strech my esophegus. I tend to eat soft foods and stay away from steak or anything chewy. I have congestive heart failure, sudden cardiac death, syncope all of which I greatfully managed to survive. I have fibromyalgia, and some nodules on my chest wall ( i forget what that is called) I have had 5 or 6 bouts with Costochrondritus which was way worse than actually having my heart stop. Costo hurts like a beech! I am frequently short of breath, exercize intolerant and have trouble holding my water.I have good dsys and bad days. Also my left hand and the base of my scalp goes all numb and tingly sometimes. There is also a terrible electric shock type feeling in my mid back area that makes me completely stop in my tracks and feel like I have been hit with a 350 lb pro football player. I have been hypokalimic after taking water pills (Ferosimide) i have taken prendisone for the Chosto and feel better immediatly, but I have mental reactions to too much Prendisone. I am very allergic to NSAID'S and pennicillian. Anyone got any ideas that the Drs have maybe not thought of... I would sure like to get better and go dance but the last time I danced I lasted 3 minutes before I had to fall into a chair.
  • Does benadryl work for pet dander? (1 answer)
    hi I have been taking Benadryl or pet dander? It seemed to work well even if I only take one tablet. Does anyone also find that taking one tablet does not make you drowsy? How often should I take one tablet of Benadryl which is 25 mg? has anyone found any other allergy medication that work or pet dander? Thank you very much.

More questions for: Benadryl, Oxycodone Hydrochloride

You may be interested at these reviews (Write a review):

  • Diphenhydramine and mental acuity
    For at least 10 years, I have taken diphenhydramine 50 mg. at bedtime for insomnia and allergies. The results have been that I sleep well with no hangover or any cognitive impairment. If I experience vertigo from allergies, I may take an additional 50 mg. but never exceeding 100 mg in a 24 hour period.

    After reading the report regarding an Alzheimer's study finding that after taking as little as 4mg diphenhydramine daily for more than 3 years, dementia rates were high.

    I stopped the diphenhydramine one night. I experienced symptoms of deep brain pulsating pain and severe insomnia. After 4 hours, I took 50 mg diphenhydramine and slept very well. The next night I took 37.5 mg. diphenhydramine, slept very well. However, some of my tasks require layers of mental challenges in which I became slower.

    My question is how did the study recipients obtain 4 mg doses of diphenhydramine when the standard over-the-counter (OTC) availability in tablets is 25 mg? How reliable is the information submitted from the study subjects? What manufacturer's diphendramine was used, or were there several?

    I felt sharper mentally when on 50 mg daily than so far on 37.5 mg.
  • Oxycontin induced low blood pressure.
    Have taken for 10+ years (Oxycontin). Recently had dose raised by 50%. I now take 140mg 3xdaily and 60mg (immediate Release) x4 daily as needed. Almost immediately after changing dosing (3-5 days later) I began to feel dizzy and light headed. BP began to lower and is now at 89/58. I have been treated in the past for having high BP so this is significantly lower than usual. The ONLY other change in diet, medication and lifestyle is at the same time I stopped consuming regular Coke and have switched to Diet Dr. pepper. Same caffeine levels but not same sugar levels.
  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless
  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

More reviews for: Benadryl, Oxycodone Hydrochloride

Comments from related studies:

  • From this study (5 months ago):

  • Possible stomach blockage, pharmaceutical bezoar.
    Oxycontin 30 mg every 12 hours is far less effective than oxycodone 15 mg every 6 hours.

    Reply

  • From this study (9 months ago):

  • 27 L knee operations, three massive L knee infections resulting in a third and final arthoplasty revision. Extensive soft tissue damage resulting in perminante subqutanious sutuers and locking full leg brace, also perminante.

    Daily swelling in the knee joint (4 to 6 cm daily). Constant pain as well as additional pain when walking.

    Reply

  • From this study (1 year ago):

  • Past distal injuries returning with increased pressure symptoms. Eye pain with movement. Increased pressure and pain with neck movement. Connective tissue disease - Ehlers Danlos Syndrome.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Oxycodone Hydrochloride (oxycodone hydrochloride) is often used to treat pain. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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