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Review: Pepcid and Zantac

This review analyzes the effectiveness and drug interactions between Pepcid and Zantac. It is created by eHealthMe based on reports of 1,308 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Pepcid and Zantac >>>

What are the drugs

Pepcid (latest outcomes from 22,823 users) has active ingredients of famotidine. It is often used in gastroesophageal reflux disease.

Zantac (latest outcomes from 35,508 users) has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease.

On Sep, 21, 2014: 1,307 people who take Pepcid, Zantac are studied

Pepcid, Zantac outcomes

Drug combinations in study:
- Pepcid (famotidine)
- Zantac (ranitidine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pepcid is effectiven/an/an/an/a0.00%
(0 of 1 people)
Zantac is effective0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DehydrationAnaemiaHepatic FailureLeukopeniaDepressionOesophagitisAbdominal AbscessPain
SepsisCerebral HaemorrhageMetastases To LiverAnxietyPyrexiaHilar LymphadenopathyAneurysm RupturedNausea
HypotensionEnterocolitisOral SurgeryGallbladder DisorderChillsFatigueBronchial HaemorrhageAnxiety
HyperbilirubinaemiaHepatic Function AbnormalHaemoglobin DecreasedCholecystitis ChronicVitamin D DeficiencyPleurisySepsisFatigue
Mucosal InflammationRenal Failure AcuteHaematocrit DecreasedAbdominal PainCalcium DeficiencyPneumonitisSplenic HaemorrhageVomiting
Cystitis HaemorrhagicBlood Lactic Acid IncreasedPainAnhedoniaDyspepsiaUrinary IncontinenceDyspnoea
Cytomegalovirus InfectionLymphadenopathyGingivitisHeart Rate IrregularOsteoporosisTremorAnaemia
Renal FailureMedullary Thyroid CancerGamma-glutamyltransferase IncreasedLymphoceleDysphagiaPneumothoraxDepression
Drug IneffectiveHaemoglobin DecreasedOsteomyelitisRelapsing-remitting Multiple SclerosisPoor Quality SleepDysphagiaGastrooesophageal Reflux Disease
Bk Virus InfectionThyroidectomyAspartate Aminotransferase IncreasedNeutropeniaGastric DisorderDysarthriaPyrexia

Drug effectiveness by gender :

Pepcid is effective0.00%
(0 of 1 people)
Zantac is effective0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions by gender * :

Back PainFatigue
Weight DecreasedInjury
Oedema PeripheralDyspnoea

Drug effectiveness by age :

Pepcid is effectiven/an/an/an/a0.00%
(0 of 1 people)
Zantac is effectiven/an/an/an/a0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions by age * :

PyrexiaDeathElectrocardiogram Qt ProlongedCholecystitis ChronicConvulsionArthralgiaDepressionPain
PneumoniaOesophagitisHaemolytic AnaemiaVomitingPainNauseaPainNausea
PainOverdoseBlood Bilirubin IncreasedPainOsteopeniaType 2 Diabetes MellitusArthralgiaAnxiety
Failure To ThriveVomiting ProjectileAspartate Aminotransferase IncreasedNauseaAstheniaChest PainOsteonecrosis Of JawBone Disorder
Incision Site InfectionStreptococcal Infection NosPainAnxietyInsomniaFatigueAnxietyPyrexia
IrritabilityIrritabilityAlanine Aminotransferase IncreasedDiarrhoeaDepressionPainNauseaWeight Decreased
HypotensionKidney Infection NosAbdominal PainJaundiceWeight DecreasedVomitingBack PainAnaemia
Fluid OverloadRenal Failure NosAgitationInjuryDysphagiaDyspnoeaFatigueRenal Failure Acute
HypertensionApnoeaVomitingHeadacheDrug DependenceDepressionDyspnoeaPneumonia
LethargyCholecystitis ChronicLymphadenopathyNauseaHeadacheInjuryDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Pepcid and Zantac?

Can you answer these questions (what is this?):

More questions for: Pepcid, Zantac

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Complete drug side effects:

On eHealthMe, Pepcid (famotidine) is often used to treat gastroesophageal reflux disease. Zantac (ranitidine hydrochloride) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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