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Review: Percocet and Skelaxin

This review analyzes the effectiveness and drug interactions between Percocet and Skelaxin. It is created by eHealthMe based on 652 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 16, 2014: 652 people who take Percocet, Skelaxin are studied

Percocet, Skelaxin outcomes

Drug combinations in study:
- Percocet (acetaminophen; oxycodone hydrochloride)
- Skelaxin (metaxalone)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Percocet is effective33.33%
(2 of 6 people)
33.33%
(1 of 3 people)
40.00%
(2 of 5 people)
57.14%
(4 of 7 people)
0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
n/a100.00%
(1 of 1 people)
Skelaxin is effective0.00%
(0 of 6 people)
0.00%
(0 of 7 people)
0.00%
(0 of 4 people)
33.33%
(1 of 3 people)
50.00%
(1 of 2 people)
50.00%
(1 of 2 people)
n/a100.00%
(1 of 1 people)

Drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dizziness
(5 reports)

Coma
(5 reports)

Deafness
(5 reports)

Burning Sensation
(5 reports)

Sleep Talking
(4 reports)

Weight Decreased
(4 reports)

Abdominal Discomfort
(4 reports)

Intervertebral Disc Protrusion
(4 reports)

Sleep Disorder
(4 reports)

Insomnia
(4 reports)

Anxiety
(2 reports)

Constipation
(2 reports)

Agitation
(1 report)

Impaired Memory
(1 report)

Dry Mouth
(1 report)

Loss Of Appetite
(1 report)

Occipital Neuralgia
(1 report)

Urinary Hesitation
(1 report)

Testicular Disorder
(1 report)

Urinary Retention
(1 report)

Anxiety
(3 reports)

Depression
(3 reports)

Deep Vein Thrombosis
(2 reports)

Pulmonary Embolism
(2 reports)

Mood Swings
(1 report)

Intentional Overdose
(1 report)

Hallucination
(1 report)

Aggression
(1 report)

Weight Increased
(1 report)

Pain
(1 report)

Respiratory Distress
(2 reports)

Drug Withdrawal Syndrome
(2 reports)

Agitation
(2 reports)

Mental Status Changes
(1 report)

Loss Of Consciousness
(1 report)

Disorientation
(1 report)

Bundle Branch Block Left
(1 report)

Bundle Branch Block Right
(1 report)

Muscle Spasms
(1 report)

Overdose
(1 report)

Amnesia
(2 reports)

Depression
(2 reports)

Anxiety
(2 reports)

Aggression
(2 reports)

Decreased Appetite
(1 report)

Paranoia
(1 report)

Alopecia
(1 report)

Acne
(1 report)

Fat Tissue Increased
(1 report)

Confusional State
(1 report)

Gallbladder Disorder
(3 reports)

Pain
(3 reports)

Pancreatitis
(3 reports)

Cholecystitis Chronic
(3 reports)

Sphincter Of Oddi Dysfunction
(3 reports)

n/aPain
(220 reports)

Anxiety
(184 reports)

Back Pain
(143 reports)

Emotional Distress
(134 reports)

Hypertension
(110 reports)

Osteonecrosis Of Jaw
(107 reports)

Bone Disorder
(98 reports)

Nausea
(97 reports)

Injury
(97 reports)

Osteomyelitis
(95 reports)

Drug effectiveness by gender :

FemaleMale
Percocet is effective44.44%
(8 of 18 people)
37.50%
(3 of 8 people)
Skelaxin is effective16.67%
(3 of 18 people)
14.29%
(1 of 7 people)

Drug interactions by gender * :

FemaleMale
Pain
(219 reports)

Anxiety
(180 reports)

Back Pain
(129 reports)

Hypertension
(124 reports)

Nausea
(121 reports)

Emotional Distress
(117 reports)

Depression
(109 reports)

Fatigue
(102 reports)

Spinal Osteoarthritis
(100 reports)

Pain In Extremity
(99 reports)

Anxiety
(43 reports)

Pain
(37 reports)

Back Pain
(35 reports)

Arthralgia
(33 reports)

Dyspnoea
(33 reports)

Insomnia
(32 reports)

Nausea
(31 reports)

Fatigue
(30 reports)

Headache
(29 reports)

Drug Withdrawal Syndrome
(29 reports)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Percocet is effectiven/an/an/a25.00%
(2 of 8 people)
14.29%
(4 of 28 people)
50.00%
(2 of 4 people)
25.00%
(1 of 4 people)
66.67%
(2 of 3 people)
Skelaxin is effectiven/an/an/a12.50%
(1 of 8 people)
7.14%
(2 of 28 people)
25.00%
(1 of 4 people)
0.00%
(0 of 4 people)
0.00%
(0 of 2 people)

Drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes Mellitus
(1 report)

n/aPain
(6 reports)

Cholecystitis Chronic
(5 reports)

Emotional Distress
(3 reports)

Sphincter Of Oddi Dysfunction
(3 reports)

Gallbladder Disorder
(3 reports)

Pancreatitis
(3 reports)

Weight Increased
(3 reports)

Dyspnoea
(2 reports)

Cholelithiasis
(2 reports)

Back Pain
(2 reports)

Cholecystitis
(12 reports)

Insomnia
(9 reports)

Urinary Tract Infection
(8 reports)

Influenza Like Illness
(8 reports)

Cardiac Failure Congestive
(8 reports)

Bronchitis
(8 reports)

Blood Cholesterol Increased
(7 reports)

Presyncope
(7 reports)

Multi-organ Failure
(7 reports)

Mass
(7 reports)

Anxiety
(32 reports)

Drug Withdrawal Syndrome
(28 reports)

Pain
(27 reports)

Depression
(26 reports)

Headache
(25 reports)

Arthralgia
(25 reports)

Drug Dependence
(22 reports)

Pyrexia
(22 reports)

Dyspnoea
(22 reports)

Agitation
(21 reports)

Pain
(103 reports)

Depression
(78 reports)

Anxiety
(76 reports)

Hypoaesthesia
(70 reports)

Back Pain
(68 reports)

Nausea
(58 reports)

Oedema Peripheral
(51 reports)

Muscle Spasms
(51 reports)

Osteomyelitis
(50 reports)

Arthralgia
(46 reports)

Pain
(43 reports)

Emotional Distress
(41 reports)

Fall
(39 reports)

Nausea
(38 reports)

Diarrhoea
(35 reports)

Anxiety
(34 reports)

Anaemia
(34 reports)

Hypertension
(29 reports)

Anhedonia
(29 reports)

Rash
(27 reports)

Anxiety
(69 reports)

Pain
(65 reports)

Back Pain
(56 reports)

Dyspnoea
(49 reports)

Emotional Distress
(47 reports)

Anhedonia
(45 reports)

Fall
(43 reports)

Osteomyelitis
(42 reports)

Spinal Osteoarthritis
(42 reports)

Diarrhoea
(41 reports)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Percocet, Skelaxin

You can also:

Complete drug side effects:

On eHealthMe, Percocet (acetaminophen; oxycodone hydrochloride) is often used to treat pain. Skelaxin (metaxalone) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

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