eHealthMe - FDA and Social Media, Personalized eHealthMe - a cloud computing service for drugs

FDA and Social Media, Personalized

Advanced tools
Drugs A-Z       Conditions A-Z       Side effects A-Z       Symptoms A-Z

Home > Plaquenil > Naproxen > Plaquenil and Naproxen

Review: Plaquenil and Naproxen

This review analyzes the effectiveness and drug interactions between Plaquenil and Naproxen. It is created by eHealthMe based on reports of 755 people who take the same drugs from FDA and social media, and is updated regularly.

What are the drugs

Plaquenil (what 15,492 Plaquenil users reported?) has active ingredients of hydroxychloroquine sulfate. It is used in systemic lupus erythematosus.

Naproxen (what 21,898 Naproxen users reported?) has active ingredients of naproxen. It is used in pain.

On Sep, 13, 2014: 755 people who take Plaquenil, Naproxen are studied

Plaquenil, Naproxen outcomes

Drug combinations in study:
- Plaquenil (hydroxychloroquine sulfate)
- Naproxen (naproxen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Plaquenil is effective0.00%
(0 of 2 people)
(2 of 6 people)
(0 of 4 people)
(2 of 5 people)
(1 of 7 people)
(0 of 4 people)
(1 of 1 people)
Naproxen is effective0.00%
(0 of 2 people)
(2 of 5 people)
(0 of 3 people)
(1 of 5 people)
(1 of 6 people)
(1 of 4 people)
(2 of 3 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
EosinophiliaSmall Cell Lung Cancer Stage UnspecifiedGastrointestinal HaemorrhageAtrial FibrillationRetinal DetachmentMalaiseItchingNausea
HypersensitivityAtrial FibrillationSpondylosisCoronary Artery DiseaseGoiterCoughHyperlipidaemiaPain
Blood Alkaline Phosphatase IncreasedCardiac Failure CongestiveDegenerative Joint DiseaseChest PainItchingNight SweatsGoiterArthralgia
Aspartate Aminotransferase IncreasedTachycardiaOsteoarthritisDyspnoeaBradycardiaPolypFatigueHeadache
Alanine Aminotransferase IncreasedRetroperitoneal FibrosisFibromyalgiaThrombophlebitisFatigueRetroperitoneal FibrosisThroat TightnessDyspnoea
RashPolypOtotoxicityDuodenal UlcerShortness Of BreathBurning Mouth SyndromeShortness Of BreathFatigue
HyperlipidaemiaCoughPalpitationsMood AlteredThroat TightnessFibromyalgiaProteinuriaUrinary Tract Infection
PalpitationsMalaiseSkin ReactionGastrointestinal Haemorrhage NosWeightSpondylosisDrug Ineffective
Muscle PainNight SweatsMuscle PainPyloric UlcerDegenerative Joint DiseaseRheumatoid Arthritis
Skin ReactionBurning Mouth SyndromeEmotional DistressOsteoarthritisPain In Extremity

Drug effectiveness by gender :

Plaquenil is effective23.08%
(6 of 26 people)
(0 of 3 people)
Naproxen is effective26.92%
(7 of 26 people)
(0 of 3 people)

Most common drug interactions by gender * :

PainDrug Ineffective
ArthralgiaRheumatoid Arthritis
Urinary Tract InfectionOedema Peripheral
Pain In ExtremityChest Pain
VomitingAtrial Fibrillation
DyspnoeaJoint Swelling
Rheumatoid ArthritisCoronary Artery Disease

Drug effectiveness by age :

Plaquenil is effectiven/an/a0.00%
(0 of 4 people)
(2 of 7 people)
(1 of 8 people)
(2 of 5 people)
(1 of 14 people)
(0 of 10 people)
Naproxen is effectiven/an/a25.00%
(1 of 4 people)
(1 of 7 people)
(2 of 20 people)
(2 of 5 people)
(1 of 12 people)
(0 of 10 people)

Most common drug interactions by age * :

n/aUpper Respiratory Tract Infection NosDermatitis NosPyrexiaNauseaPain In ExtremityUrinary Tract InfectionPneumonia
Autoimmune HepatitisNauseaProteinuriaHeadacheBack PainRheumatoid ArthritisDyspnoea
PyrexiaVomiting NosDiarrhoea NosPainHeadacheNauseaArthralgia
Infection NosChest PainAtelectasisArthralgiaPainVomitingDysphagia
Chest PainSystemic Lupus ErythematosusDyspnoeaAlopeciaAnxietyArthralgiaPain
Muscle CrampsSweating IncreasedAnaemiaNeck PainInjection Site Reaction NosFatiguePulmonary Fibrosis
Abdominal Pain NosArthralgiaDrug IneffectiveTemporomandibular Joint SyndromeDyspnoeaOsteomyelitisFall
Drug IneffectiveLung InfiltrationDepressionFallDrug IneffectivePain In Extremity
Renal Papillary NecrosisPleuritic PainUrinary Tract InfectionMental Status ChangesPainParaesthesia
Urinary Tract InfectionFatigueConvulsionMusculoskeletal StiffnessFractureUpper Respiratory Tract Infection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Plaquenil and Naproxen?

Get connected! Join a mobile support group:
- group for people who take Plaquenil and Naproxen
- group for people who take Naproxen
- group for people who take Plaquenil

Comments from related studies:

  • From this study (13 months ago):

  • I am having most of the symptoms of Hypothyroid, weight gain, very dry skin & hair, easily stressed, palpitations yet my doctor tells me my bloods are normal. No one seems to know why I am feeling so bad all the time.


  • From this study (1 year ago):

  • eosinophilia bowel problems with pain lethargic


  • From this study (2 years ago):

  • For years my high blood pressure was under control with 80MG of Lisinopril. I stopped smoking 11-01-2011 and started getting headaches. I also stopped taking the RA medications. I ended up in the hospital with BP of 212 over 152. in Dec. 2011. Now May 2012), I monitor my BP. Three weeks after stopping Prednisone again the headaches and High Blood Pressure is back. I go off the prednisone because I cannot lose weight which makes my diabetes worse and also makes my hypertension worse.


Can you answer these questions (what is this?):

More questions for: Naproxen, Plaquenil

You may be interested at these reviews (what is this?):

  • Eczema and birth control-microgestin
    I started getting eczema over the last year and recently decided it may be from the birth control as well, which I started taking @ 2 months before I got the eczema and skin started breaking out...weight gain, etc. I am on singulair, westcort cream, moisture/kenalog, exederm cream, cerevue wash, cet ...

  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Horrific nightmares taking naproxen
    I've Taking naproxen 500mg twice a day for 3 weeks on a course for 6 months, I've been having horrific dreams worse than horrer movies, the most recent is involving my ex & current partner where I had a psychotic stalker (my ex) switched around because in the dream I dump my partner for my ex, well ...

More reviews for: Naproxen, Plaquenil

Complete drug side effects:

On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Naproxen (naproxen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

About - Terms of service - Privacy policy - Press - Advertise - Apps - Testimonials - Contact us

© 2014 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.