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Related topic: Fluconazole, Prednisone

Review: Prednisone and Fluconazole

This review analyzes the effectiveness and drug interactions between Prednisone and Fluconazole. It is created by eHealthMe based on 3,221 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 27, 2014: 3,221 people who reported to have interactions when taking Prednisone, Fluconazole are studied

Trend of Prednisone, Fluconazole's drug interactions, side effects and effectiveness reports (4445871)

Drug combinations in study:
- Prednisone (prednisone)
- Fluconazole (fluconazole)

eHealthMe real world results:

Most common interactions experienced by people in the use of Prednisone, Fluconazole:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)1,127
Dyspnoea (difficult or laboured respiration)992
Arthralgia (joint pain)860
Anaemia (lack of blood)591
Nausea (feeling of having an urge to vomit)536
Fatigue (feeling of tiredness)470
Osteonecrosis Of Jaw (death of bone of jaw)437

Most common interactions experienced by people in long term use of Prednisone, Fluconazole:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)16
Encephalopathy (functioning of the brain is affected by some agent or condition)10
Oral Candidiasis (fungal infection of mouth)10
Protein Urine Present10
Generalised Oedema (swelling all over the body)10
Confusional State8
Conjunctivitis (pink eye)6

How effective are the drugs:

not at allsomewhatmoderatehighvery high

Top conditions involved for these people * :

  1. Diffuse large b-cell lymphoma
  2. Rheumatoid arthritis
  3. Prophylaxis
  4. Pain
  5. Multiple myeloma

Top co-used drugs for these people * :

  1. Diflucan
  2. Acyclovir
  3. Heparin sodium injection
  4. Nexium
  5. Aspirin

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Prednisone (prednisone) is often used to treat rheumatoid arthritis. Fluconazole (fluconazole) is often used to treat vaginal yeast infection. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (5 months ago):

  • Hives started on left temple and right lower jaw bone. Next day started underneath my chin. Had some small bumps...itched, hurt. Two days later rash/hives spread to arms, hands, chest and around waist. I had small areas on both hands that resembled blisters. Tried Prednisone and after first round of 40mg for five days, ended up in a Prednisone shot and put me on a step down Prednisone starting at 60mg. Second day in I started having GI bleeding through my bowels and had to stop Prednisone. Went to dermatologist and she gave me another type of steroid shot, put me on Betamethasone Dipropionate Lotion .05% and Hydroxyzine 10mg. The hives and rash has pretty much gone away, however I had darkened areas on face where all of it started. My waist still has dark red look to it. It doesn't itch or hurt anymore. I never scratched my face at all in fear of scaring, but did all other areas of my body. I was reading on line trying to research what could have caused reaction. I was taken off all meds and have not started back on any of them. I am currently using the Betamethasone lotion.


  • From this study (6 months ago):

  • Took one pill Diflucan and it knocked my rash out in about 20 ninutes, about 10 minutes later i broke out in boils on Right ankle and right foot, both hands and elbows, on face but not as much. I showered once and between thigh area boiled before this happened I heard sizzling in shower.
    But after the diflucan it dissapeard, so went to ER because I had boils in places I had in the past around the time I was on the medication, I wouldnt have taken it, but has been years, and wasnt thinking. So the ER gives me prednisone for 10 days. On my last day I took it, I was back in ER for severe chest pain which hurt my collarbone. Got several answers as to why this happened, maybe someone experienced a similar situation. I also have several medical conditions that are painful.


  • From this study (7 months ago):

  • This will be the third day taking the drugs.


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Fluconazole side effects
- Prednisone side effects



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