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Review: Prednisone and Vicodin

This review analyzes the effectiveness and drug interactions between Prednisone and Vicodin. It is created by eHealthMe based on reports of 8,154 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Prednisone and Vicodin >>>

What are the drugs

Prednisone (what 149,890 Prednisone users reported?) has active ingredients of prednisone. It is used in rheumatoid arthritis.

Vicodin (what 35,288 Vicodin users reported?) has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain.

On Aug, 17, 2014: 8,154 people who take Prednisone, Vicodin are studied

Prednisone, Vicodin outcomes

Drug combinations in study:
- Prednisone (prednisone)
- Vicodin (acetaminophen; hydrocodone bitartrate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Prednisone is effective27.50%
(11 of 40 people)
(8 of 27 people)
(0 of 4 people)
(5 of 12 people)
(4 of 14 people)
(10 of 15 people)
(5 of 8 people)
Vicodin is effective34.38%
(11 of 32 people)
(7 of 19 people)
(7 of 15 people)
(8 of 18 people)
(4 of 22 people)
(2 of 10 people)
(3 of 8 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainHeadachePainOsteonecrosisCellulitisAnxietyAbdominal TendernessPain
DyspnoeaPneumoniaSkin TightnessDizzinessAnxietyDepressionInjection Site AbscessAnxiety
HeadachePainNephrogenic Systemic FibrosisCerebrovascular AccidentDepressionCellulitisConstipationNausea
AnaemiaDyspnoeaActivities Of Daily Living ImpairedAnxietyDeep Vein ThrombosisPostoperative Wound ComplicationNauseaDyspnoea
InjuryPain In ExtremityParaesthesiaHypotensionOsteomyelitisEndocarditis BacterialPneumonitisArthralgia
AnxietyNauseaDeformityOsteomyelitisLoss Of ConsciousnessEmotional DistressHypoxiaFatigue
NauseaFebrile NeutropeniaInjuryEye DisorderBack PainRenal Failure AcuteGait DisturbanceBack Pain
Pain In ExtremityConstipationBack PainGait DisturbanceDizzinessImpaired HealingLung InfiltrationAsthenia
PneumoniaSepsisHypoaesthesiaMyocardial IschaemiaNeck PainSepsisFaeces DiscolouredOedema Peripheral
FatigueVisual DisturbanceAstheniaAtrial FibrillationEndocarditis BacterialImmunosuppressionAbdominal DiscomfortAnaemia

Drug effectiveness by gender :

Prednisone is effective38.89%
(35 of 90 people)
(8 of 30 people)
Vicodin is effective32.61%
(30 of 92 people)
(12 of 33 people)

Most common drug interactions by gender * :

Oedema PeripheralBack Pain
Back PainPneumonia

Drug effectiveness by age :

Prednisone is effectiven/an/a33.33%
(1 of 3 people)
(3 of 12 people)
(5 of 20 people)
(8 of 45 people)
(12 of 96 people)
(14 of 33 people)
Vicodin is effectiven/an/a25.00%
(1 of 4 people)
(6 of 15 people)
(7 of 19 people)
(8 of 46 people)
(11 of 97 people)
(9 of 33 people)

Most common drug interactions by age * :

Congenital Cystic Kidney DiseaseInflammatory Bowel DiseaseCholecystitis ChronicPainArthralgiaPainPainPain
Premature BabyCrohn's DiseaseNauseaDeep Vein ThrombosisNauseaAnxietyAnxietyAnxiety
Meningitis NeonatalPostoperative IleusVomitingAnxietyPainHeadacheNauseaDyspnoea
ThrombocytopeniaWeight DecreasedAbdominal Pain UpperDyspnoeaAnxietyFatigueOedema PeripheralPneumonia
Respiratory DistressGastrointestinal Stoma ComplicationPainNauseaPyrexiaDepressionArthralgiaAsthenia
Maternal Drugs Affecting FoetusHyponatraemiaAnxietyPulmonary EmbolismDyspnoeaNauseaFatigueNausea
Neonatal Respiratory Distress SyndromeInfusion Related ReactionCholelithiasisFatigueBack PainBack PainAnaemiaFall
Foetal Growth RetardationHeart Rate AbnormalGallbladder DisorderInjuryChest PainArthralgiaBack PainBack Pain
PancreatitisDrug HypersensitivityAbdominal PainHeadacheAbdominal PainAstheniaDiarrhoeaFatigue
GastritisRespiratory ArrestPulmonary EmbolismVomitingDepressionDyspnoeaBone DisorderAnaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Prednisone and Vicodin
- group for people who take Prednisone
- group for people who take Vicodin

Comments from related studies:

  • From this study (6 days ago):

  • Steroid dependent asthmatic,sight deterioration after glaucoma surgery in both eyss.Joints deterioration i believe from steroids,Ehasted after walking 10 steps.Heart rate climbs to 160-170 after getting up and walking 10 steps.Sitting rate 110 bpm.Weight 220 height 5'10".weight was 180 before using steroids.


  • From this study (3 weeks ago):

  • I went to a Rheumatologist and he said I have Hashimoto disease and said its not serious enough to take meds for. The test is - Thyroid Peroxidase Antiboties - my number is 363. It says that is should be <9. I was wondering if these medications I am on could be causing abnormal reading. I do have severe inflammation due to serious injuries.


  • From this study (4 weeks ago):

  • I believe alot of my symptoms are related but after seeing 7 different specialists and them running many different tests I still don't have a diagnosis. Many of the tests are abnormal but nothing seems to fit completely together. My gastroenterologist is referring me to a surgeon for severe gastro reflux that can't be controlled with medication. I can't take the ferrous sulfate because of nausea.


    rossta75 on Jul, 21, 2014:

    I'm not sure what state you live in but I have researched this same issue and THC the active ingredient in Marijuana and a few other active chemicals will calm the stomach and increase appetite. I'm not a user but I am considering it under medical advice.


Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Can i connect by email with other patients that have hypoglycemia and stevens-johnson syndrome?
    I have had hypoglycemia since childhood, and I have managed it easily until just this weekend. I got S-J two years ago from Bactrim. As I have healed from S-J very slowly and painfully, I was exercising hard, and working hard and slipped a little on not eating enough protein. I started dropping into ...

  • Can my symptoms actually pinpoint a cause/condition?
    I would just like insight on this. I'm on pain management right now, but it's just to manage the pain. Every thing else has really been not taken serious by any physican it office I've been to. Is this normal stuff many woman go through? I'm just sick of feeling like this between the constant pain & ...

  • Does anyone else (besides me) get 'good energy' from taking acetaminophen 325mg ?
    30 minutes after taking one 10mg Vicodin (Hydrocodone)and 325 mg Acetaminophen I get a gradual increase of energy which lasts up to 2 hours. I like this effect because I have COPD and degenerative disk disease and the energy allows me to get more accomplished on my daily 'to-do' list than if I hadn' ...

More questions for: Prednisone, Vicodin

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  • Prednisone mixed results-it lets me breath
    have been on prednisone now for 3 years straight. Am taking 30mg a day just to breath. every time i have tried to taper off i have ended up in the emergency room unable to breath. That has been 7 times in the last year. I am 49 years old and was in good health 3-4 years ago. got a cough and it has b ...

  • Prednisone side effects
    Took this for 6 days, tapering at the end to treat a rash caused by a spider bite. The heartburn started on day 1 but the other symptoms didn't begin until day 4. None we're severe but they weren't fun either. The blurred vision was worst.

  • Xanax bed wetting will it stop and do i wear diapers or die
    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts. Just want to bleed out and not hur ...

More reviews for: Prednisone, Vicodin

Complete drug side effects:

On eHealthMe, Prednisone (prednisone) is often used to treat rheumatoid arthritis. Vicodin (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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