From FDA reports: drug interactions between Prevacid and Hydrochlorothiazide
This is a real world study of Prevacid and Hydrochlorothiazide drug interactions. The study is created by eHealthMe based on 2,174 reports from FDA.
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What are the drugs
Prevacid has active ingredients of lansoprazole. It is used in gastroesophageal reflux disease, gastric ulcer, gastroesophageal reflux in infants, gastritis, reflux gastritis, indigestion.
Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is used in high blood pressure, fluid retention, swelling, foot, leg, and ankle swelling, diuretic effect, diuretic therapy.
On Jun, 8, 2013: 2,174 people who reported to have interactions when taking Prevacid, Hydrochlorothiazide are studied

Drug combinations in study:
- Prevacid (lansoprazole)
- Hydrochlorothiazide (hydrochlorothiazide)
Most common interactions experienced by people in the use of Prevacid, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Dyspnoea | 426 |
| 2 | Anxiety | 369 |
| 3 | Hypertension | 363 |
| 4 | Diarrhoea | 332 |
| 5 | Nausea | 276 |
| 6 | Chest Pain | 245 |
| 7 | Pain | 227 |
| 8 | Fatigue | 199 |
| 9 | Anaemia | 189 |
| 10 | Gastrooesophageal Reflux Disease | 142 |
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Most common interactions experienced by people in long term use of Prevacid, Hydrochlorothiazide:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Dyspnoea | 18 |
| 2 | Deep Vein Thrombosis | 16 |
| 3 | Pulmonary Embolism | 8 |
| 4 | Blood Glucose Increased | 7 |
| 5 | Pain In Extremity | 6 |
| 6 | Insomnia | 6 |
| 7 | Fatigue | 6 |
| 8 | Emotional Distress | 6 |
| 9 | Depression | 5 |
| 10 | Oedema Peripheral | 5 |
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Top conditions involved for these people * :
- Hypertension
- Gastrooesophageal reflux disease
- Pain
- Rheumatoid arthritis
- Depression
Top co-used drugs for these people * :
- Aspirin
- Seroquel
- Lipitor
- Vioxx
- Lisinopril
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Next: personalize this study to your gender and age OR ask a question from Patients Like You
Side effects in real world:
On eHealthMe, Prevacid (lansoprazole) is often used to treat gastroesophageal reflux disease. Hydrochlorothiazide (hydrochlorothiazide) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
Other drugs that are used to treat the same conditions:
Related personalized Q&As (what is this?):
- Has taking prevacid caused me to have gall bladder pain
(for a 71 year old man who has Gallbladder Pain, and takes Prevacid)
Have taken Prevacid for 1 month. Sever Pain in right side unable to get comfortable. Not kidney stone. Doc did Urine test, clear. Today I did not take a Prevacid & pain is receding rapidly. Ultrasound scheduled for Monday.(Members of the personal health network: 374)
- Is there anything i can take for sunblock while taking hydroclorothizide?
(for a 57 year old man who has Red Itchy Rash That Develops From The Sun Using Sunblock And Taking Hydrochlorothiazide, and takes Hydrochlorothiazide, Requip, Carvedilol, Gabapentin, Zolpidem Tartrate)
I develop a red itchy rash while in the sun using sunblock and taking Hydro. I would like to have some sort of protection from the sun , as I tend to be outside a lot. Any help or suggestion would be appreciated. Thanks!(Members of the personal health network: 3,329)
- Is it safe to take verapamil, clariyhromycin, flagyl and prilosec at the same time?
(for a 66 year old woman who has High Blood Pressure, Paroxysmal Supraventricular Tachycardia (PSVT), and takes Hydrochlorothiazide, Verapamil Hydrochloride)
I have been diagnosed with h pylori and was prescribed clarithromycin, flagyl and prilosec for 2 weeks. I have read that this treatment is very difficult. I am worried about mixing these drugs with the verapamil and hydrochlorothiazide. Not sure what to do. Has anyone had this problem.(Members of the personal health network: 6,735)
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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