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Review: Doxycycline and Prograf

Summary: drug interactions are reported among people who take Doxycycline and Prograf together.

This review analyzes the effectiveness and drug interactions between Doxycycline and Prograf. It is created by eHealthMe based on reports of 103 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Doxycycline and Prograf >>>

What are the drugs

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. (view latest outcomes from 13,672 users)

Prograf has active ingredients of tacrolimus. It is often used in liver transplant. (latest outcomes from Prograf 20,081 users)

On Dec, 20, 2014: 103 people who take Doxycycline, Prograf are studied

Doxycycline, Prograf outcomes

Drug combinations in study:
- Doxycycline (doxycycline hyclate)
- Prograf (tacrolimus)

Drug effectiveness over time :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Stenotrophomonas InfectionStenotrophomonas InfectionIntervertebral Disc ProtrusionPostoperative IleusCardiac Arrestn/an/aAnaemia
Engraft FailurePulmonary HaemorrhageOsteopeniaRenal Failure AcuteMemory ImpairmentHypoaesthesia
Pulmonary HaemorrhageEngraft FailureOvarian CystDevice Related InfectionConfusional StateIntervertebral Disc Protrusion
Muscular WeaknessBiopsy Breast AbnormalOsteoarthritis
ExostosisBreast Cancer FemaleAbscess
Blood Creatinine IncreasedAnaemiaDyspnoea
Post Procedural HaemorrhageEyelid OedemaOpen Wound
AbscessHaemorrhoidsGingival Disorder
Skin UlcerOsteoarthritisFlank Pain
DiarrhoeaNeck PainPain In Jaw

Drug effectiveness by gender :


Most common drug interactions by gender * :

Intervertebral Disc ProtrusionHypoaesthesia
Biopsy Breast AbnormalGingival Disorder
Breast Cancer FemaleFlank Pain
OsteopeniaAortic Aneurysm
Ovarian CystImpaired Healing
PainTooth Disorder
AlopeciaPain In Jaw
Weight IncreasedAnaemia
OsteoarthritisOpen Wound

Drug effectiveness by age :


Most common drug interactions by age * :

n/an/an/aHodgkin's DiseaseIntervertebral Disc ProtrusionHypoaesthesiaAspergillosisOsteonecrosis Of Jaw
HypoaesthesiaOvarian CystStress Urinary IncontinenceComplications Of Transplanted KidneyOsteomyelitis
Joint DislocationOsteopeniaAdenomyosisSkin CancerAnaemia
LymphadenopathyAnaemiaSerositisStenotrophomonas InfectionOpen Wound
Foreign Body In EyeBiopsy Breast AbnormalMemory ImpairmentEngraft FailurePain In Jaw
DyspnoeaBreast Cancer FemaleConfusional StatePulmonary HaemorrhageImpaired Healing
AmnesiaOsteoarthritisDizzinessPemphigoidBack Pain
Chest PainErythema Of EyelidCardiac ArrestSepsisTooth Disorder
Corneal AbrasionNeck PainInjuryKidney Transplant RejectionAortic Aneurysm
Neuropathy PeripheralHaemorrhoidsRhinitis AllergicDiabetes MellitusFlank Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Doxycycline and Prograf?

You are not alone! Join a related mobile support group:
- support group for people who take Doxycycline and Prograf
- support group for people who take Doxycycline
- support group for people who take Prograf

Can you answer these questions (Ask a question):

More questions for: Doxycycline, Prograf

You may be interested at these reviews (Write a review):

  • My experience with lyme
    My final semester at college-

    Woke up to extreme inflammation in what was determined to be a portion of my trapezius on the left side length of my next. It was accompanied by severely swollen lymph nodes throughout my entire body. I went about my day with what to me was seemingly a bad neck cramp and oncoming cold. In the afternoon I decided to participate in Track practice and what occurred after I am unsure about in terms of its relation to me performing physically or an autoimmune response against my peripheral nervous system. The next morning I woke up the left side of my trapezius was completely dysfunctional from its attachment to my cranium all the way down to the mid point of my back. It was accompanied by inflammation and sore pain at the point where the next connects to the shoulder girdle. Over the course of the next 8 months I went undiagnosed with Lyme, having seen neurologists and orthopedics in an attempt to find a solution. Reflecting on the first three months, I experienced significant effects on my emotional stability and cognitive capability. I would have severe mood swings--rage, depression, excitement-- and I would have difficulty with memory and train of thought- all of which can be confirmed by multitude of classmates. By the 8 month mark I had began to feel mild joint pain, particularly in areas I had formerly injured in athletic activity (ankles, lower back). At this point, my accessory nerve had not regenerated in terms of the portion affecting my trapezius, didn't regain any lost muscle function. I saw my physician, who discovered the Lyme infection. I took doxycycline over the next 3 months and saw significant improvement in my trapezius, which was accompanied by a decrease in lymph node size, as proven by comparison of MRIs. My fatigue dissipated and my moods/cognition returned to normal. I've regained about 70% of the function I formerly had with my trapezius (as compared to 0% prior to treatment). I wanted to write this because I have yet to see a similar case, understand the ambiguity of Lyme disease and the array of conditions it causes.
  • Symptons from taking doxycyclin
    I recently went in for a physical, everything was normal except my Creatinine levels. I had severe symptoms from burning hands/knuckles to feeling very tingly like cold needles. Also, burned very easily from sun even with 50 sun screen applied. Should I be worried about the Creatinine levels be abnormally high?
  • Rituxan mental changes (1 response)
    Within a month my daughter has had altered mental health symptoms such as confusion 'ADD symptoms' decrease in vision, trouble concentrating, frequent headaches and sharp head pain, forgetfulness, blanks out much more and 'feels off'
    it has now been about 5 months since last rituxan
  • Low platelet blood count
    Kidney transplant had been performed 10 years ago.Mycophenolate mofetil was introduced 5 years ago to replace azathioprine.It has caused various undesirable side effects like severe diarrhea,nausea,nose and gum bleeding and low platelet count.Most of them were reduced as soon as the dose decreased except from the low platelet count which seriously concerns me as it has gone almost down the lowest limit.
  • Suicide attempted at first then sadly completed from prograf
    The mother of my 12 year old son had a very successful career and recently received her 3rd kidney transplant after the previous kidney which lasted over 20 years had eventually succumbed to a chronic kidney disease. She had a very successful career as an RN and then a Nurse Anesthetist. Had a bright future and retirement and college plans etc. for herself and our son. House and vehicles paid off etc.

    She received a transplant which she waited 5 years on dialysis for. Still strong in her career and household and my sons care during those 5 years as well. Once she received her transplant and was prescribed Prograf 1 year ago her life changed dramatically. Confusion, severe depression, loss of focus crying several times a day. She pleaded about every month or so with the doctor to greatly reduce the Prograf or put her back on Immuran which worked well for her the previous 20 plus years. The doctor repeatedly told her there are no mental side effects associated with Prograf and that is was her and her kidney is fine. She went to see a therapist which did not help. She kept pleading the doctor for help including her family and loved ones pleading for her as well explaining how it dramatically changed her mentally. Sadly she began thinking her mind was irrecoverable from the damage from Prograf and started to think she would be a burden to her son and her family. The very ones she has always helped all these years. 6 weeks ago she attempted suicide driving her vehicle into a creek. She was admitted to a psychiatric hospital. A few days later released. She again pleaded with the doctor along with family members explaining how bad it is getting. Also visited a renal doctor locally she knew for her entire career. It was hard to do this as she was embarrassed about her condition but was desperate for help. Unfortunately that doctor to all of our surprise told her to go back to the first doctor and to persist with them. Sadly this was the last straw, she gave up, thinking she was mentally damaged for life despite all of us begging her to hold on til we found a doctor willing to help with something other than Prograf. She committed suicide a few days later. Leaving her son whom she loved and treasured more than anything. She left two suicide notes, one to her son explaining she was only going to hinder his life as she was now incapable of any kind of adult life and especially caring for him. She apologized of course but told him how absolutely special he is and to never ever change. She expressed her pride in him etc. and said she will always be watching him and keep sending signs of this. We believe she does.

More reviews for: Doxycycline, Prograf

Complete drug side effects:

On eHealthMe, Doxycycline (doxycycline hyclate) is often used to treat acne. Prograf (tacrolimus) is often used to treat liver transplant. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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