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Review: taking Promethazine and Mucinex D together

Summary: drug interactions are reported among people who take Promethazine and Mucinex D together.

This review analyzes the effectiveness and drug interactions between Promethazine and Mucinex D. It is created by eHealthMe based on reports of 9 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Promethazine and Mucinex D >>>

On Mar, 28, 2015: 9 people who take Promethazine, Mucinex D are studied

Promethazine, Mucinex D outcomes

Drug combinations in study:
- Promethazine (promethazine hydrochloride)
- Mucinex D (guaifenesin; pseudoephedrine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Promethazine is effectiven/a0.00%
(0 of 1 people)
Mucinex D is effectiven/a100.00%
(1 of 1 people)

Drug effectiveness by gender :

Promethazine is effective0.00%
(0 of 1 people)
Mucinex D is effective100.00%
(1 of 1 people)

Drug effectiveness by age :

Promethazine is effectiven/an/an/an/a0.00%
(0 of 1 people)
Mucinex D is effectiven/an/an/an/a100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
CholelithiasisNasal Congestion
Abdominal Pain UpperCholecystitis Chronic
AstheniaAbdominal Pain
Meningitis Cryptococcal

Most common drug interactions by gender * :

CholelithiasisLiver Function Tests Nos Abnormal
InjuryRespiratory Distress
Abdominal PainHepatic Failure
VomitingHaemoglobin Decreased
ArthralgiaBlood Urea Increased
Cholecystitis ChronicDepression Aggravated
PainBlood Creatinine Increased
Meningitis Cryptococcal
Nasal Congestion

Most common drug interactions by age * :

n/an/an/aPyrexiaCholecystitis ChronicNasal Congestionn/aLiver Function Tests Nos Abnormal
CholelithiasisPainArthralgiaRespiratory Distress
Vena Cava ThrombosisAbdominal PainMeningitis CryptococcalHepatic Failure
Deep Vein ThrombosisInjuryCoughHaemoglobin Decreased
VomitingCholelithiasisRigorsBlood Urea Increased
Abdominal Pain UpperVomitingRespiratory Tract CongestionDepression Aggravated
CholecystitisWhite Blood Cells Urine PositiveBlood Creatinine Increased
AstheniaWhite Blood Cell Count Increased
NauseaBlood Urine Present

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Promethazine and Mucinex D?




You are not alone! Join a related support group:
- support group for people who take Mucinex D
- support group for people who take Promethazine

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Promethazine (promethazine hydrochloride) is often used to treat nausea. Mucinex D (guaifenesin; pseudoephedrine hydrochloride) is often used to treat sinus congestion. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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