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Review: taking Dexamethasone and Promethazine together

Summary: drug interactions are reported among people who take Dexamethasone and Promethazine together.

This review analyzes the effectiveness and drug interactions between Dexamethasone and Promethazine. It is created by eHealthMe based on reports of 1,114 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. (latest outcomes from 53,459 Dexamethasone users)

Promethazine hydrochloride has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from 452 Promethazine hydrochloride users)

On Feb, 1, 2015: 1,114 people who take Dexamethasone, Promethazine Hydrochloride are studied

Dexamethasone, Promethazine Hydrochloride outcomes

Drug combinations in study:
- Dexamethasone (dexamethasone)
- Promethazine Hydrochloride (promethazine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dexamethasone is effective0.00%
(0 of 2 people)
(1 of 1 people)
Promethazine Hydrochloride is effective0.00%
(0 of 2 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaAstheniaNormochromic Normocytic AnaemiaAbdominal PainPulmonary Hypertensionn/an/aPain
DyspnoeaPneumoniaNeuritisFood IntoleranceWeight IncreasedAnxiety
VomitingMalignant Neoplasm ProgressionOedema PeripheralVomitingEjection Fraction DecreasedNausea
Renal ImpairmentFailure To ThriveActinomycosisCholecystitis ChronicDry MouthOsteonecrosis Of Jaw
FatigueAcute Respiratory FailureOsteomyelitisNauseaAlveolitis AllergicAnaemia
PainDyspnoeaOsteitisPainCardiac Valve DiseaseBack Pain
Anti-erythropoietin Antibody PositiveSepsisMouth UlcerationGallbladder DisorderCardiac FailureDyspnoea
Perinephric AbscessVomitingMean Cell Volume IncreasedHypersensitivityAsthenia
NephrolithiasisBack PainKlebsiella InfectionBone Disorder
DepressionOedema PeripheralInflammationFatigue

Drug effectiveness by gender :

Dexamethasone is effective33.33%
(1 of 3 people)
Promethazine Hydrochloride is effective0.00%
(0 of 3 people)

Most common drug interactions by gender * :

Osteonecrosis Of JawNausea
Back PainDehydration
DyspnoeaOsteonecrosis Of Jaw
Bone DisorderPneumonia

Drug effectiveness by age :

Dexamethasone is effectiven/an/an/an/an/a0.00%
(0 of 10 people)
(1 of 1 people)
Promethazine Hydrochloride is effectiven/an/an/an/an/a0.00%
(0 of 10 people)
(0 of 1 people)

Most common drug interactions by age * :

n/aCataract UnilateralDrug Clearance DecreasedAstheniaNauseaPainPainPain
Multi-organ FailurePainAnaemiaHypoaesthesiaAnxietyAnxietyAnxiety
Hydrocephalus NosInjuryUrinary Tract InfectionParaesthesiaNauseaAnaemiaBack Pain
Blindness CorticalPulmonary EmbolismNauseaLymphadenopathyOsteonecrosis Of JawNauseaAnaemia
Respiratory Failure (excl Neonatal)AnxietyConjunctivitis ViralNeuropathy PeripheralBack PainNeuropathy PeripheralOsteonecrosis Of Jaw
Retinal DetachmentWeight IncreasedDeep Vein ThrombosisMetastases To Central Nervous SystemVomitingOsteonecrosis Of JawDyspnoea
NauseaChemical Burn Of SkinInsomniaAlanine Aminotransferase IncreasedInjuryInjuryFall
Wound Infection NecPost-traumatic Stress DisorderDyspnoeaAspartate Aminotransferase IncreasedDyspnoeaHeadacheBone Disorder
CellulitisDepressionPainDrug DependencePyrexiaDental CariesFatigue
Haemorrhage NosBlisterVomitingMucosal InflammationDepressionDiarrhoeaOsteomyelitis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Dexamethasone and Promethazine?

You are not alone! Join a related mobile support group:
- support group for people who take Dexamethasone and Promethazine
- support group for people who take Dexamethasone
- support group for people who take Promethazine Hydrochloride

Can you answer these questions (Ask a question):

More questions for: Dexamethasone, Promethazine Hydrochloride

You may be interested at these reviews (Write a review):

  • Roaring in the ears from tramadol (taken with dexamethasone)
    It seems the roaring in my right ear happens more around taking the tramadol (2-3/day). Of course, I have a (5) day regiment of dexamethasone at (2/day) so maybe there's a connection. This was prescribed by my GP ( highly regarded) for severe lower back bulging disc pain and down left leg. Also prescribed tizanidine for muscle spasms and gabapentin for, maybe nerve swelling? Both at 2/day but I take less of these two.

    Back pain much better but have the roaring in right ear and can't sleep much. Also doing the Dr recommended exercises daily. Will follow up with chiropractic if this doesn't get me there.

    This is a chronic condition, maybe 20 years, no specific injury, just an accumulation of doing dumb things in my youth.
  • Fibromyalgia & related health issues (3 responses)
    Fibromyalgia dx after pregnancy of only child at 42/other dx followed and seem to be in conjunction. heart issues did not appear until after the use of fibro meds- cymbalta, lyrica, neurontin, and more. had 1 seizure believed to be related to seretonin syndrome/years and years of mistreatment by doctors. unable to recall how many docs and meds through the years. one other very significant issue- after tooth extraction had puncture to left maxillary sinus-after YEARS of neglect by docs, found max. & ethmoid sinus completely opaque on CAT scan. Had surgery. Now, years later, have mucous plug that sporadically comes out upon sneezing. Fairly recent CAT scan shows sinuses again completely opaque. Certain needs further attention, but basically afraid to go through surgery again. Also- may have had heart attack. ER visit said no, but shortly after, had abnormal ekg. Again, neglect from docs. Am now active advocate for fm/chronic pain patients. Disgusted by the whole lack of interest of medical community. Looking for answers through my own research to try to find a way to improve quality of life...
  • Husband died from depakene
    My husband took Depakene and Mysoline (Phenobarital) for 28 years. No hospital or physician checked his ammonia levels during these years. Ammonia levels needed to be checked every 6 months when taking Valproic Acid.

    As the result of no ammonia levels taken, he suffered from moderate severe atrophy of the brain, metabolic system was destroyed, regular system destroyed, 25 diagnoses due to the side effects of Depakene and died one year ago of mitochondrial encephalopathy.

More reviews for: Dexamethasone, Promethazine Hydrochloride

Comments from related studies:

  • From this study (12 months ago):

  • Developed symptoms of hyperventation syndrome (need to take frequent deep satisfying deep breaths- not rapid breathing) after hospital stay for flu and possible meningitis. My chest x ray and CBC is normal. One doc tried to tell me this was PTSD/anxiety from post hospitalization. It is not. I am not anxious except for fact that I cannot breath right. I do not have pneumonia. I have never had this before, but I'm even short of breath while talking to people and distracted - still needing to take deep breaths mid conversation. I have never had some of the above drugs before and wondered if they could have anything to do with it. Thank you.


    srandall on Mar, 13, 2014:

    I am a Caucasian female age 42. On vanco 3rd time for 3weeks this time. First week this time can't breathe normally, stays n cat scan clear, ringing, popping in ears n loss of hearing, frequent urination and way more urine volume. Dr Denys any of these symptoms from vanco as he gives lectures on vanco. I also had kidney function decreases n he says he would prescribe even if kidneys in half failure because vanco is the best! Sending him documents from Mayo saying after 10 days on vanco patients need to be monitored for hearing, kidney and shallow breathing. Maybe he can add to his lectures.


  • From this study (3 years ago):

  • Tceleste on Nov, 25, 2011:

    I became very agitated on taxol and carboplatin. I also take Ativan rarely. I take zofran, claritin and Neulasta. I take Mobic (meloxicam) and percocet for pain. I have continuously moved even when I am so tired I can barely chew. It is not a seizure type movement. I am either cleaning, organizing or planning to clean and organize. I feel as though I have been given a nesting hormone, when in fact all estrogen has been taken from me and I had both ovaries and my complete omentum removed. My son commented on me as well as several friends. The thing I think about is that for at least 2 and a half years I was very sick. By the time I was diagnosed I was already Stage IIIb. I feel like my old normal energy is returning since I had so much cancer removed by surgery and now the chemo is working because my hair is falling out, which to me is reassuring. I have to disclipine myself to rest and not be always organizing my house. I think the lady who helps me clean is going to fire me because by the time she gets here there is little to do. If I were not as disclipined as I am about making myself rest, this could be a bigger problem.



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Complete drug side effects:

On eHealthMe, Dexamethasone (dexamethasone) is often used to treat multiple myeloma. Promethazine Hydrochloride (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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