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Review: Dexamethasone and Promethazine

This review analyzes the effectiveness and drug interactions between Dexamethasone and Promethazine. It is created by eHealthMe based on 1,111 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 5, 2014: 1,111 people who reported to have interactions when taking Dexamethasone, Promethazine Hydrochloride are studied

Trend of Dexamethasone, Promethazine Hydrochloride's drug interactions, side effects and effectiveness reports (18467432)

Drug combinations in study:
- Dexamethasone (dexamethasone)
- Promethazine Hydrochloride (promethazine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Dexamethasone, Promethazine Hydrochloride:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety1,111
Asthenia (weakness)1,005
Pain988
Dyspnoea (difficult or laboured respiration)940
Osteonecrosis Of Jaw (death of bone of jaw)816
Nausea (feeling of having an urge to vomit)744
Anaemia (lack of blood)715
Back Pain698
Bone Disorder588
Osteomyelitis (infection of bone)582

Most common interactions experienced by people in long term use of Dexamethasone, Promethazine Hydrochloride:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Vomiting5
Nausea (feeling of having an urge to vomit)5
Food Intolerance (inability to have food)5
Pain5
Cholecystitis Chronic (long lasting infection of gallbladder)5
Gallbladder Disorder5
Abdominal Pain5
Dry Mouth4
Weight Increased4
Cardiac Valve Disease (heart valve disease)4

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Dexamethasone0.00%0.00%100.00%0.00%0.00%
Promethazine Hydrochloride0.00%100.00%0.00%0.00%0.00%

Top conditions involved for these people * :

  1. Nausea
  2. Pain
  3. Multiple myeloma
  4. Premedication
  5. Metastases to bone

Top co-used drugs for these people * :

  1. Decadron
  2. Phenergan
  3. Zofran
  4. Zometa
  5. Phenergan hcl

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Dexamethasone, Promethazine Hydrochloride

You can also:

Complete drug side effects:

On eHealthMe, Dexamethasone (dexamethasone) is often used to treat multiple myeloma. Promethazine Hydrochloride (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (3 weeks ago):

  • Developed symptoms of hyperventation syndrome (need to take frequent deep satisfying deep breaths- not rapid breathing) after hospital stay for flu and possible meningitis. My chest x ray and CBC is normal. One doc tried to tell me this was PTSD/anxiety from post hospitalization. It is not. I am not anxious except for fact that I cannot breath right. I do not have pneumonia. I have never had this before, but I'm even short of breath while talking to people and distracted - still needing to take deep breaths mid conversation. I have never had some of the above drugs before and wondered if they could have anything to do with it. Thank you.

    Reply

    srandall on Mar, 13, 2014:

    I am a Caucasian female age 42. On vanco 3rd time for 3weeks this time. First week this time can't breathe normally, stays n cat scan clear, ringing, popping in ears n loss of hearing, frequent urination and way more urine volume. Dr Denys any of these symptoms from vanco as he gives lectures on vanco. I also had kidney function decreases n he says he would prescribe even if kidneys in half failure because vanco is the best! Sending him documents from Mayo saying after 10 days on vanco patients need to be monitored for hearing, kidney and shallow breathing. Maybe he can add to his lectures.

    Reply

  • From this study (2 years ago):

  • Tceleste on Nov, 25, 2011:

    I became very agitated on taxol and carboplatin. I also take Ativan rarely. I take zofran, claritin and Neulasta. I take Mobic (meloxicam) and percocet for pain. I have continuously moved even when I am so tired I can barely chew. It is not a seizure type movement. I am either cleaning, organizing or planning to clean and organize. I feel as though I have been given a nesting hormone, when in fact all estrogen has been taken from me and I had both ovaries and my complete omentum removed. My son commented on me as well as several friends. The thing I think about is that for at least 2 and a half years I was very sick. By the time I was diagnosed I was already Stage IIIb. I feel like my old normal energy is returning since I had so much cancer removed by surgery and now the chemo is working because my hair is falling out, which to me is reassuring. I have to disclipine myself to rest and not be always organizing my house. I think the lady who helps me clean is going to fire me because by the time she gets here there is little to do. If I were not as disclipined as I am about making myself rest, this could be a bigger problem.

    Tceleste

    Reply

  • From this study (3 years ago):

  • I have advanced Rheumatoid Arthritis. My Left wrist swelled painfully. Had a negative X-ray so Dr (fully informed for current drug regimens and allergies--Aspirin, Penicillin, Thoradamides, Ornate, Iodine, Latex) Within 5-10 min of getting 2 shots containing: Nubain, Phenergan, and Decadron, I presented with Severe Dystonia, in all parts of my body, in the car on the way home with my 22 yr old son driving. For the next 7 hours he watched me flail, scream in the most terrifying sounds he says he’s ever heard and survive severe Faecal incontinence, severe vomiting, and pain of 9 to 10 without relief. The Drs in Hospital who figured it out had were ready to intubate me and force a chemical coma so my body wouldn’t syrcome. By Gods grace things turned around. 7 hours later I awoke to my sons reassuring face, and a Dr saying that he hopes I never remember it all, it was so painful for him to watch. My heart could have stopped; I just came out of Congestive heart failure in January. I’m on 3L O2 24/7 and my lungs are ready to give out. Why are these drugs even given together?

    By Kathleen O’Donnell
    mrsodee@hotmail.com
    replies welcomed

    Reply

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- Dexamethasone side effects
- Promethazine Hydrochloride side effects

 

 

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