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Review: Propranolol and Zanaflex

This review analyzes the effectiveness and drug interactions between Propranolol and Zanaflex. It is created by eHealthMe based on reports of 258 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Propranolol and Zanaflex >>>

What are the drugs

Propranolol hydrochloride (latest outcomes from 3,288 users) has active ingredients of propranolol hydrochloride. It is often used in stress and anxiety.

Zanaflex (latest outcomes from 7,296 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

On Sep, 15, 2014: 258 people who take Propranolol Hydrochloride, Zanaflex are studied

Propranolol Hydrochloride, Zanaflex outcomes

Drug combinations in study:
- Propranolol Hydrochloride (propranolol hydrochloride)
- Zanaflex (tizanidine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Propranolol Hydrochloride is effective0.00%
(0 of 1 people)
(2 of 5 people)
(2 of 2 people)
(0 of 4 people)
(2 of 2 people)
(0 of 1 people)
Zanaflex is effective50.00%
(1 of 2 people)
(0 of 1 people)
(2 of 5 people)
(0 of 3 people)
(2 of 5 people)
(0 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypotensionInjuryDrowsinessRapid Deep Breathing (hyperventilation)Heart Rate Decreasedn/aRapid Deep Breathing (hyperventilation)Pain
DysphagiaAnhedoniaFlatulenceDeathMigraineExhaustion, Fatigue, Lethargy, Tiredness, WearinessDepression
Spinal OsteoarthritisPainFatigueRheumatoid ArthritisHeadacheWeight Gain - UnintentionalNausea
Muscle SpasmsPathological GamblingSeromaDehydrationGlomerular Filtration Rate DecreasedHeadache
Tongue SpasmAnxietyShort-term Memory LossExhaustion, Fatigue, Lethargy, Tiredness, WearinessDiverticulitisAnxiety
Muscle TwitchingObsessive-compulsive DisorderShort-term Memory LossGastric UlcerArthralgia
Loss Of ConsciousnessFearConfusionNauseaAgitation
Blood Pressure IncreasedDepressionWeight Gain - UnintentionalUrticariaInsomnia
OverdoseEmotional DistressFatigueVulvovaginal Burning SensationHypertension
Sinus ArrestDeep Vein ThrombosisWeight DecreasedVomiting

Drug effectiveness by gender :

Propranolol Hydrochloride is effective27.27%
(3 of 11 people)
(3 of 4 people)
Zanaflex is effective23.08%
(3 of 13 people)
(2 of 5 people)

Most common drug interactions by gender * :

HeadacheDrug Dependence
PyrexiaDrug Withdrawal Syndrome
ArthralgiaDisturbance In Attention

Drug effectiveness by age :

Propranolol Hydrochloride is effectiven/an/an/a100.00%
(3 of 3 people)
(2 of 15 people)
(0 of 3 people)
(1 of 5 people)
(0 of 3 people)
Zanaflex is effectiven/an/an/a75.00%
(3 of 4 people)
(0 of 15 people)
(1 of 4 people)
(1 of 6 people)
(0 of 3 people)

Most common drug interactions by age * :

WeaknessWeight IncreasedHeadacheHeadachePainGlomerular Filtration Rate Decreased
Urinary Tract InfectionDepressionArthralgiaNauseaDepressionBlood Triglycerides Abnormal
Difficulty In WalkingTremorAnxietyArthralgiaDrug IneffectiveHeart Rate Decreased
OverdoseHypertensionVision BlurredDrug DependenceCarpal Tunnel SyndromeDiverticulitis
Drug Administration ErrorHeart Rate IrregularMigraineConstipationDehydrationDiarrhoea
General Physical Health DeteriorationChest PainNauseaFallWeight IncreasedColitis Ulcerative
FatigueMalaiseAccidental OverdoseVomitingAngina PectorisDehydration
FibromyalgiaDrug DependenceOedema PeripheralOsteoporosisMigraine

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Propranolol and Zanaflex?

Get connected! Join a mobile support group:
- group for people who take Propranolol and Zanaflex
- group for people who take Propranolol Hydrochloride
- group for people who take Zanaflex

Comments from related studies:

  • From this study (5 months ago):

  • Cerebral palsy- hemiplegic/temporal lobe seizures, migraines, insomnia, depressed, sad, in pain all day. I have no intention of intention of wanting to do anything except stay in bed and sleep and I'm never hungry.


  • From this study (2 years ago):

  • Have started getting petechiae and blood blisters on my forearms.


  • From this study (2 years ago):

  • heroin & alcohol addiction problems - not currently using. overusing lorazepam, extremely sedated. disoriented.


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Complete drug side effects:

On eHealthMe, Propranolol Hydrochloride (propranolol hydrochloride) is often used to treat migraine. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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