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Home > Ritalin > Benadryl > Ritalin and Benadryl

Review: Ritalin and Benadryl

This review analyzes the effectiveness and drug interactions between Ritalin and Benadryl. It is created by eHealthMe based on reports of 325 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Ritalin and Benadryl >>>

What are the drugs

Ritalin (latest outcomes from 11,193 users) has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder.

Trend of ritalin reports

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Trend of benadryl reports

On Oct, 26, 2014: 325 people who take Ritalin, Benadryl are studied

Ritalin, Benadryl outcomes

Drug combinations in study:
- Ritalin (methylphenidate hydrochloride)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Ritalin is effective50.00%
(2 of 4 people)
(4 of 8 people)
(2 of 2 people)
(4 of 8 people)
(4 of 4 people)
(2 of 3 people)
(1 of 1 people)
Benadryl is effective25.00%
(3 of 12 people)
(2 of 2 people)
(0 of 3 people)
(3 of 3 people)
(0 of 1 people)
(1 of 1 people)
(0 of 2 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConvulsionDisease RecurrenceSuicidal IdeationIrritabilityDrug Effect DecreasedAortic Valve StenosisFeeling AbnormalChest Pain
AggressionUrticariaVomitingInsomniaFatigueExhaustion, Fatigue, Lethargy, Tiredness, WearinessDisabilityBack Pain
Foaming At MouthMalignant HypertensionTardive DyskinesiaObsessive-compulsive DisorderDry ThroatDizzinessBipolar DisorderDyspnoea
AgitationVomitingAnhedoniaAnhedoniaCoughHeadacheSuicidal BehaviourFatigue
Tardive DyskinesiaCarpal Tunnel SyndromePsychomotor HyperactivityFluid RetentionDry MouthHypertensionOsteonecrosis Of Jaw
DizzinessGastrointestinal HaemorrhageManiaTardive DyskinesiaDecreased AppetiteLearning DisabilitySuicidal Ideation
ApnoeaActivated Partial Thromboplastin Time ProlongedNervousnessDecreased InterestMood SwingsPain In Extremity
Exhaustion, Fatigue, Lethargy, Tiredness, WearinessRenal Artery StenosisDisorientationNasal UlcerMental DisorderDepression
HeadacheSleep DisorderNumbness And TinglingRespiratory FailureCryingFall
BronchospasmUmbilical HerniaDepressionType 2 Diabetes MellitusDepressed MoodMetastases To Bone

Drug effectiveness by gender :

Ritalin is effective76.92%
(10 of 13 people)
(9 of 17 people)
Benadryl is effective66.67%
(8 of 12 people)
(2 of 13 people)

Most common drug interactions by gender * :

FatigueBipolar Disorder
Chest PainDisability
DyspnoeaFeeling Abnormal
Back PainAgitation
ArthralgiaLearning Disability
Osteonecrosis Of JawMental Disorder
Pain In ExtremitySuicidal Behaviour
Intervertebral Disc DegenerationCrying
Metastases To BoneSuicidal Ideation
FallDepressed Mood

Drug effectiveness by age :

Ritalin is effectiven/a25.00%
(1 of 4 people)
(6 of 10 people)
(3 of 5 people)
(3 of 11 people)
(2 of 23 people)
(1 of 2 people)
(3 of 3 people)
Benadryl is effectiven/a25.00%
(1 of 4 people)
(3 of 9 people)
(0 of 4 people)
(2 of 6 people)
(0 of 23 people)
(1 of 2 people)
(3 of 3 people)

Most common drug interactions by age * :

AggressionUrticariaWeight IncreasedMouth UlcerationMemory ImpairmentAnxietySomnolenceBack Pain
ConvulsionGastrointestinal HaemorrhageSuicidal IdeationDeep Vein ThrombosisAstheniaDepressionSuicidal IdeationFatigue
PneumoniaActivated Partial Thromboplastin Time ProlongedDiabetes MellitusMalaiseFatiguePain In ExtremityDepressionMetastases To Bone
Diabetic ComplicationInfusion Related ReactionAggressionLactic AcidosisGait DisturbanceGastrooesophageal Reflux DiseaseGun Shot WoundArthritis
Cholecystitis ChronicMastoiditisDystoniaGastrooesophageal Reflux DiseaseHypoaesthesiaPainFeeling AbnormalWeight Decreased
DyspnoeaConvulsionDrug IneffectiveDiabetes MellitusDyspnoeaBladder DisorderChest PainArthralgia
BradycardiaAbdominal PainAngerOral HerpesParaesthesiaFallAnxietyOsteonecrosis Of Jaw
HypotensionCarpal Tunnel SyndromeHepatic SteatosisPalpitationsConfusional StatePyrexiaBipolar DisorderChronic Obstructive Pulmonary Disease
Renal ImpairmentDisease RecurrenceAgitationOedema PeripheralVision BlurredSuicidal IdeationVision BlurredOsteoporosis
TremorAgitationIrritabilityLacrimation IncreasedConvulsionNauseaInsomniaOsteosclerosis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Ritalin and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Ritalin and Benadryl
- support group for people who take Benadryl
- support group for people who take Ritalin

Can you answer these questions (Ask a question):

More questions for: Benadryl, Ritalin

You may be interested at these reviews (Write a review):

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    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I ...

  • Benadryl completed suicide 50 year old
    (Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

  • Had nms in 2005, will trileptal increase chance of recurrence?
    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

  • Seroquel made me weird, indifferent to everything.
    (Posted by a 19 year old girl who has Schizotypal Personality Disorder, and takes Concerta)
    With constant anxiety. I found myself not wanting to be nice to my family, hearting them and seeing the consecuences later , rather than before. I remember wearing a wig to the nutritionist, "just because".

  • Temporal lobe epilepsy in concerta
    (Posted by a 8 year old boy who has ADHD, and takes Concerta)
    My son is 8 years old and has ADHD with severe hyperactivity and impulsivity. He has been on meds since he was 5. We started with Foculin, switched to Daytrana patch and just recently (with the help of his Psychiatrist) decided to try Concerta. We stopped the Daytrana and began titration onto Conc ...

More reviews for: Benadryl, Ritalin

Complete drug side effects:

On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Benadryl, Ritalin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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