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Review: Ritalin and Wellbutrin

This review analyzes the effectiveness and drug interactions between Ritalin and Wellbutrin. It is created by eHealthMe based on reports of 1,516 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Ritalin and Wellbutrin >>>

What are the drugs

Ritalin (latest outcomes from 11,175 users) has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder.

Wellbutrin (latest outcomes from 54,897 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

On Oct, 28, 2014: 1,516 people who take Ritalin, Wellbutrin are studied

Ritalin, Wellbutrin outcomes

Drug combinations in study:
- Ritalin (methylphenidate hydrochloride)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Ritalin is effective32.26%
(10 of 31 people)
(22 of 56 people)
(11 of 29 people)
(14 of 37 people)
(23 of 48 people)
(17 of 20 people)
(13 of 20 people)
(2 of 3 people)
Wellbutrin is effective11.11%
(2 of 18 people)
(9 of 40 people)
(3 of 26 people)
(13 of 37 people)
(25 of 58 people)
(18 of 35 people)
(16 of 28 people)
(2 of 5 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
AnxietyDiabetes MellitusType 2 Diabetes MellitusCholelithiasisFatigueFatigueWeight Gain - UnintentionalDepression
FatigueSuicidal IdeationArthralgiaAnxietyAnxietyHypertoniaDry MouthNausea
HeadacheInsomniaDiabetes MellitusIrritabilityIrritabilityGrand Mal ConvulsionErectile DysfunctionAnxiety
ManiaSomnolenceMemory ImpairmentConvulsionMemory ImpairmentPostictal StateInsomniaFatigue
InsomniaConvulsionSuicidal IdeationDeafnessDepressionSleep DisorderOverdosePain
DepressionType 2 Diabetes MellitusSexual DysfunctionChemotherapyDizzinessDrug ToxicityConvulsionFall
Suicidal IdeationAbdominal PainNeuropathy PeripheralDepressionConfusional StateBlood Caffeine IncreasedIrritabilityBack Pain
DizzinessAnxietyDepressionDiverticulumBlood Lactate Dehydrogenase IncreasedPainExhaustion, Fatigue, Lethargy, Tiredness, WearinessVomiting
Immunocomplex Mediated HypersensitivityNeuropathy PeripheralHyperglycaemiaCataractDiarrhoeaDizzinessHot FlashesChest Pain
Grand Mal ConvulsionHypertensionHerniaEndometrial DisorderDecreased AppetiteVision BlurredHypertensionDizziness

Drug effectiveness by gender :

Ritalin is effective41.10%
(67 of 163 people)
(41 of 78 people)
Wellbutrin is effective35.88%
(61 of 170 people)
(27 of 77 people)

Most common drug interactions by gender * :

DizzinessConfusional State
InsomniaDisturbance In Attention
AstheniaVision Blurred

Drug effectiveness by age :

Ritalin is effectiven/an/a42.86%
(9 of 21 people)
(16 of 62 people)
(15 of 104 people)
(38 of 133 people)
(24 of 81 people)
(8 of 43 people)
Wellbutrin is effectiven/an/a26.32%
(5 of 19 people)
(10 of 64 people)
(18 of 103 people)
(29 of 139 people)
(18 of 79 people)
(8 of 37 people)

Most common drug interactions by age * :

HyponatraemiaAgitationFatigueCompleted SuicideNauseaDepressionDepressionDepression
HypotensionAggressionGrand Mal ConvulsionSuicidal IdeationAnxietyAnxietyDizzinessNausea
DyspnoeaVomitingWeight IncreasedTremorDrug IneffectiveFatigueNauseaBack Pain
Diabetic ComplicationConvulsionInsomniaDrug DependenceConvulsionNauseaFatiguePain
ConvulsionDisorientationConvulsions NosHallucination, AuditoryFatigueConstipationAnxietyVomiting
Nervous System DisorderSudden DeathDiabetes MellitusFatigueSuicidal IdeationDizzinessPainFall
OrthopnoeaAbnormal Behaviour NosDrug IneffectiveMood SwingsDiabetes MellitusPainAstheniaPain In Extremity
TremorRetchingDecreased AppetiteIrritabilityDepressionPyrexiaFallConvulsion
Renal ImpairmentMemory ImpairmentRectal HaemorrhageNauseaAbdominal PainBack PainPain In ExtremityWeight Decreased
PneumoniaUrticaria NosNauseaDepression AggravatedDyspnoeaFallArthralgiaDecreased Appetite

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Ritalin and Wellbutrin?

Get connected! Join a related mobile support group:
- support group for people who take Ritalin and Wellbutrin
- support group for people who take Ritalin
- support group for people who take Wellbutrin

Can you answer these questions (what is this?):

More questions for: Ritalin, Wellbutrin

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More reviews for: Ritalin, Wellbutrin

Complete drug side effects:

On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat narcolepsy. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies:

More related studies for: Ritalin, Wellbutrin

Recent related drug comparison:

More related comparisons for: Ritalin, Wellbutrin

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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