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Review: taking Ritalin and Zoloft together

Summary: drug interactions are reported among people who take Ritalin and Zoloft together.

This review analyzes the effectiveness and drug interactions between Ritalin and Zoloft. It is created by eHealthMe based on reports of 1,192 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

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What are the drugs

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from 11,211 Ritalin users)

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from 78,343 Zoloft users)

On Jan, 25, 2015: 1,191 people who take Ritalin, Zoloft are studied

Ritalin, Zoloft outcomes

Drug combinations in study:
- Ritalin (methylphenidate hydrochloride)
- Zoloft (sertraline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Ritalin is effective25.00%
(3 of 12 people)
32.14%
(9 of 28 people)
50.00%
(8 of 16 people)
68.75%
(11 of 16 people)
50.00%
(8 of 16 people)
40.00%
(4 of 10 people)
69.23%
(9 of 13 people)
60.00%
(3 of 5 people)
Zoloft is effective20.00%
(1 of 5 people)
43.48%
(10 of 23 people)
21.05%
(4 of 19 people)
30.00%
(6 of 20 people)
27.27%
(6 of 22 people)
50.00%
(8 of 16 people)
50.00%
(3 of 6 people)
66.67%
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Serotonin SyndromeAbnormal BehaviourIrritabilityDisturbance In AttentionDepressionSluggishnessTinnitusDepression
Blood Pressure IncreasedDepressionSuicidal IdeationSexual DysfunctionChemotherapyLethargyAphasiaPain
Body Temperature IncreasedInsomniaPersonality ChangeAnxietyDeafnessYeast Infection - VaginaVertigoFatigue
Liver DisorderHyperhidrosisParanoiaHot FlushCataractDiplopiaAnemiaNausea
Alanine Aminotransferase IncreasedDrug IneffectiveAgitationLymphadenopathyDisturbance In AttentionCoughExcessive ThirstAnxiety
TachycardiaMood AlteredMemory ImpairmentMemory ImpairmentFibrocystic Breast DiseaseHeart RacingBedwettingSuicidal Ideation
TachypnoeaAnxietyHeart PoundingMaculopathyDiverticulumCognitive DeteriorationAltered Visual Depth PerceptionWeight Decreased
MydriasisAttention Deficit/hyperactivity DisorderNauseaFibrocystic Breast DiseaseBreast NecrosisChest Pressure SensationNumbness And TinglingAsthenia
HyperhidrosisEuphoric MoodDepressionEndometrial DisorderBreast MassShortness Of BreathMuscle WeaknessBack Pain
Muscle RigidityImpulsive BehaviourAggressionChemotherapyBack PainHeart PoundingArthralgiaFall

Drug effectiveness by gender :

FemaleMale
Ritalin is effective48.72%
(38 of 78 people)
45.71%
(16 of 35 people)
Zoloft is effective37.80%
(31 of 82 people)
29.03%
(9 of 31 people)

Most common drug interactions by gender * :

FemaleMale
PainDepression
DepressionCellulitis
NauseaAnxiety
FatiguePain
Back PainHypertension
Weight DecreasedAggression
AstheniaAnaemia
FallFatigue
Suicidal IdeationNausea
ArthralgiaDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Ritalin is effectiven/a12.50%
(1 of 8 people)
27.27%
(9 of 33 people)
36.59%
(15 of 41 people)
17.65%
(6 of 34 people)
36.59%
(15 of 41 people)
29.17%
(7 of 24 people)
100.00%
(2 of 2 people)
Zoloft is effectiven/a0.00%
(0 of 7 people)
22.58%
(7 of 31 people)
28.21%
(11 of 39 people)
33.33%
(10 of 30 people)
16.33%
(8 of 49 people)
12.50%
(3 of 24 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Pancreatitis AcuteWeight IncreasedWeight IncreasedAnxiety NecInsomniaDepressionPainDepression
DizzinessSuicidal IdeationDepression NecSuicidal IdeationCellulitisAnxietyPain
DyspnoeaAggressionDrug Withdrawal SyndromeIrritabilityPainDepressionVomiting
DysstasiaDrug IneffectiveDrug DependenceNauseaAstheniaFatigueNausea
Eye Movement DisorderFatigueHeadache NosChest PainChest PainArthralgiaDiarrhoea
Gastric DilatationSuicide AttemptNauseaMemory ImpairmentFallBack PainAnaemia
AggressionAbnormal BehaviourWeight IncreasedVomiting NosWeight DecreasedWeight DecreasedAsthenia
HeadacheOverdoseNeck PainAttention Deficit/hyperactivity DisorderNeck PainSomnolenceDehydration
AngerAnxietyAggressionDrug IneffectiveOedema PeripheralNauseaBack Pain
PapilloedemaAgitationPain In LimbFatigueBack PainAnaemiaInfection

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Ritalin and Zoloft?

You are not alone! Join a related mobile support group:
- support group for people who take Ritalin and Zoloft
- support group for people who take Ritalin
- support group for people who take Zoloft

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Ritalin, Zoloft

You may be interested at these reviews (Write a review):

  • The zoloft/vyvanse concoction ruined my life.
    I started taking these drugs about two months ago. I am diagnosed ADHD by a psychiatrist. I received these medications from a doctor whom I know and is married to a friend my wife. She, the doctor, gave them to me from her personal medications in a plastic baggy. I was given loose instructions for taking these on a piece of paper. I was never given the paperwork with warning signs. 10 days after starting these medications, I attacked my wife and am now separated. I am barred from seeing her and my daughter by means of a Victims Protective Order. I am a normally nonviolent person. Most who know me call me a peacemaker...a pacifist. I am still horrified by the events of that night. 15 seconds changed my life forever. I hope and pray my story helps others. Don't be naïve, as I was, when given medications. Ask questions.
  • Loss of menstruation
    Hi
    I stopped using setralin 50 µg in August 2014. (I have been taken it in 1 year for my PMS). After stopping taking the pills my period become very short in september and then desappeard. I got a funcional cyste (about 30 mm) and after 10-days treatment with progesterone I got my period in the end of oktober. Two weeks afterwards I got a spare bleeding and my gyn thought that it my be an ovulation bleeding. Anyhow I have not got my period yet. The samples taken in oktober showed low FSH and heigt E2. The doctor explained that it is posible that stopping setralin could cause this hormonal imbalance. I must say that my periods were not so regular for very long time like during that year with setralin but I had other side effects like problem with concentartion, nussea etc.
    For many years ago I was on Zoloft but I had not experienced the same problem. When I started the treatment this time they did not want to give me zoloft (because of the price). I had no choice but i experienced many symptoms from different generica of Setralin. I will meet my doctor om Monday again.
  • A life of depression and fatigue (1 response)
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • A really bad day ritalin+orange juice
    I took Ritaline, then Orange juice. I couldn't do my exam at all...
  • Soar throat after taking sertaline
    half a pill first timw. severe soar throat 2 hrs after taking 25mg

More reviews for: Ritalin, Zoloft

Comments from related studies:

  • From this study (5 months ago):

  • Kevin Peters Ph.d on Mar, 4, 2013:

    Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
    All the Best,
    K. Peters

    Reply

    chris on Jun, 4, 2011:

    i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.

    Reply

    TwoDimes on Apr, 15, 2012:

    Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -

    Reply

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Complete drug side effects:

On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat narcolepsy. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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