Review: Ritalin and Zoloft
This review analyzes the effectiveness and drug interactions between Ritalin and Zoloft. It is created by eHealthMe based on reports of 1,190 people who take the same drugs from FDA and social media, and is updated regularly.
What are the drugs
Ritalin (latest outcomes from 11,171 users) has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder.
Zoloft (latest outcomes from 78,183 users) has active ingredients of sertraline hydrochloride. It is often used in depression.
On Sep, 14, 2014: 1,189 people who take Ritalin, Zoloft are studied
Drug combinations in study:
- Ritalin (methylphenidate hydrochloride)
- Zoloft (sertraline hydrochloride)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Ritalin is effective||25.00%|
(3 of 12 people)
(8 of 27 people)
(8 of 16 people)
(11 of 16 people)
(7 of 15 people)
(4 of 10 people)
(9 of 13 people)
(3 of 5 people)
|Zoloft is effective||20.00%|
(1 of 5 people)
(10 of 22 people)
(4 of 19 people)
(6 of 20 people)
(6 of 21 people)
(8 of 16 people)
(3 of 6 people)
(2 of 3 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Serotonin Syndrome||Abnormal Behaviour||Irritability||Disturbance In Attention||Depression||Sluggishness||Tinnitus||Depression|
|Blood Pressure Increased||Insomnia||Suicidal Ideation||Sexual Dysfunction||Chemotherapy||Lethargy||Aphasia||Pain|
|Body Temperature Increased||Hyperhidrosis||Personality Change||Anxiety||Cataract||Yeast Infection - Vagina||Vertigo||Fatigue|
|Liver Disorder||Drug Ineffective||Paranoia||Hot Flush||Deafness||Diplopia||Anemia||Nausea|
|Alanine Aminotransferase Increased||Depression||Agitation||Lymphadenopathy||Disturbance In Attention||Cough||Excessive Thirst||Anxiety|
|Tachycardia||Mood Altered||Memory Impairment||Memory Impairment||Fibrocystic Breast Disease||Heart Racing||Bedwetting||Suicidal Ideation|
|Tachypnoea||Anxiety||Heart Pounding||Maculopathy||Diverticulum||Cognitive Deterioration||Altered Visual Depth Perception||Weight Decreased|
|Mydriasis||Euphoric Mood||Nausea||Fibrocystic Breast Disease||Breast Necrosis||Chest Pressure Sensation||Numbness And Tingling||Asthenia|
|Hyperhidrosis||Attention Deficit/hyperactivity Disorder||Depression||Endometrial Disorder||Breast Dysplasia||Shortness Of Breath||Muscle Weakness||Back Pain|
|Muscle Rigidity||Impulsive Behaviour||Aggression||Chemotherapy||Back Pain||Heart Pounding||Arthralgia||Fall|
Drug effectiveness by gender :
|Ritalin is effective||48.05%|
(37 of 77 people)
(15 of 34 people)
|Zoloft is effective||38.27%|
(31 of 81 people)
(9 of 30 people)
Most common drug interactions by gender * :
|Suicidal Ideation||Neck Pain|
|Arthralgia||Osteonecrosis Of Jaw|
Drug effectiveness by age :
|Ritalin is effective||n/a||12.50%|
(1 of 8 people)
(8 of 31 people)
(14 of 40 people)
(6 of 34 people)
(15 of 41 people)
(7 of 24 people)
(2 of 2 people)
|Zoloft is effective||n/a||0.00%|
(0 of 7 people)
(7 of 29 people)
(11 of 38 people)
(10 of 30 people)
(8 of 49 people)
(3 of 24 people)
(1 of 2 people)
Most common drug interactions by age * :
|Pancreatitis Acute||Weight Increased||Weight Increased||Depression Nec||Insomnia||Depression||Pain||Depression|
|Dizziness||Suicidal Ideation||Anxiety Nec||Suicidal Ideation||Cellulitis||Anxiety||Pain|
|Dyspnoea||Aggression||Drug Withdrawal Syndrome||Irritability||Pain||Depression||Vomiting|
|Eye Movement Disorder||Drug Ineffective||Drug Dependence||Chest Pain||Chest Pain||Arthralgia||Diarrhoea|
|Gastric Dilatation||Overdose||Nausea||Memory Impairment||Fall||Back Pain||Anaemia|
|Aggression||Suicide Attempt||Neck Pain||Vomiting Nos||Weight Decreased||Weight Decreased||Asthenia|
|Headache||Anxiety||Pain In Limb||Attention Deficit/hyperactivity Disorder||Neck Pain||Somnolence||Dehydration|
|Anger||Agitation||Weight Increased||Drug Ineffective||Oedema Peripheral||Nausea||Back Pain|
|Papilloedema||Abnormal Behaviour||Suicidal Ideation||Fatigue||Back Pain||Anaemia||Infection|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Comments from related studies:
From this study (1 week ago):
From this study (9 months ago):
From this study (2 years ago):
Kevin Peters Ph.d on Mar, 4, 2013:
Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
All the Best,
chris on Jun, 4, 2011:
i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.
TwoDimes on Apr, 15, 2012:
Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -
SammySushi on Jul, 10, 2012:
Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.
Christophe on Nov, 13, 2012:
I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
AUDREY on Dec, 16, 2012:
STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....
Sonya on Feb, 24, 2013:
You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.
Stillaguamish on Sep, 6, 2014:
My heart breaks for you and I'm so sorry you had to go through all that. I recently had two surgeries and was outraged at hospital treatment. I had to demand my regular meds and when they gave in, they only gave me 3 of 6
Also diagnosed with myasthenia gravis. Not treated with meds
I was prescribed Concerta first to alleviate the fatigue associated with a sleep disorder. The duraction of time I was on this medication was about twelve weeks with the first 6 weeks on a lower dose. Because I developed a tolerance to the Concerta, I was then prescribed the SR Ritalin which I took for about three to four weeks before stopping it totally. With the Concerta, I started to experience joint and muscle aches. Then with the SR Ritalin the pains became more noticeable the longer I took it consequitively. I also noticed muscle weakness numerous times when doing activities. Since I stopped these medications, I have not felt the same type of pain and have not noticed muscle weakness. Should I avoid using the non-SR Ritalin too even if at a low dose used three times a week to help with waking up in the morning?
Can you answer these questions (what is this?):
- Has anyone wioth children around age 7 had weird side effects after starting zoloft such as trichotillimania? (pulling ones own hair out)
My daughter has never had a problem with pulling her eyebrows out until starting Zoloft.
- Can you split the tablet of limitical 200mg?
I have taken 150mg or 200mg of lamitical for 25 years. I am now spliting the 200 tablet in half to make 300mg. Started sweating big time.
- Is it safe to take unisom on top of vyvanse
I have took 5 ritalin 20mg and 2 30 mg vyvanse since early this morning. It is now 1:00in the morning, I'm very tired. I have 2 toddlers that I have to take carevof. Just wanting to know if it is ok to take some unison now so I can get some sleep
You may be interested at these reviews (what is this?):
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Occasionally when I have a severe yeast infection, I get laryngitis. I am so thankful your article addresses this, as the doctors I have seen were less than receptive when I suggested a link. I do not have any of the other health concerns listed in the study, but am taking fluconazole.
- Psychosis, weight loss and topamax
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- Seroquel made me weird, indifferent to everything.
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Complete drug side effects:
On eHealthMe, Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Zoloft (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Ritalin is used in:
- Zoloft is used in:
Other drugs that are used to treat the same conditions:
- Ritalin alternatives:
- Zoloft alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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